| Vanadium and cancer treatment: antitumoral mechanisms of three oxidovanadium (IV) complexes on a human osteosarcoma cell line IE Leon, N Butenko, AL Di Virgilio, CI Muglia, EJ Baran, I Cavaco, ... Journal of inorganic biochemistry 134, 106-117, 2014 | 97 | 2014 |
| Antitumor properties of a vanadyl (IV) complex with the flavonoid chrysin [VO (chrysin) 2 EtOH] 2 in a human osteosarcoma model: the role of oxidative stress and apoptosis IE Leon, AL Di Virgilio, V Porro, CI Muglia, LG Naso, PAM Williams, ... Dalton Transactions 42 (33), 11868-11880, 2013 | 94 | 2013 |
| Oxidovanadium (IV) complexes with chrysin and silibinin: anticancer activity and mechanisms of action in a human colon adenocarcinoma model IE Leon, JF Cadavid-Vargas, I Tiscornia, V Porro, S Castelli, P Katkar, ... JBIC Journal of Biological Inorganic Chemistry 20, 1175-1191, 2015 | 87 | 2015 |
| Bacterial cellulose hydrogel loaded with lipid nanoparticles for localized cancer treatment ML Cacicedo, GA Islan, IE León, VA Alvarez, I Chourpa, E Allard-Vannier, ... Colloids and surfaces B: Biointerfaces 170, 596-608, 2018 | 82 | 2018 |
| Modified bacterial cellulose scaffolds for localized doxorubicin release in human colorectal HT-29 cells ML Cacicedo, IE León, JS Gonzalez, LM Porto, VA Alvarez, GR Castro Colloids and Surfaces B: Biointerfaces 140, 421-429, 2016 | 77 | 2016 |
| Synthesis and characterization of CaCO3–biopolymer hybrid nanoporous microparticles for controlled release of doxorubicin VE Bosio, ML Cacicedo, B Calvignac, I León, T Beuvier, F Boury, ... Colloids and Surfaces B: Biointerfaces 123, 158-169, 2014 | 66 | 2014 |
| Antiproliferative and apoptosis-inducing activity of an oxidovanadium (IV) complex with the flavonoid silibinin against osteosarcoma cells IE Leon, V Porro, AL Di Virgilio, LG Naso, PAM Williams, M Bollati-Fogolín, ... JBIC Journal of Biological Inorganic Chemistry 19, 59-74, 2014 | 66 | 2014 |
| In vitro and in vivo antitumor effects of the VO-chrysin complex on a new three-dimensional osteosarcoma spheroids model and a xenograft tumor in mice IE León, JF Cadavid-Vargas, A Resasco, F Maschi, MA Ayala, C Carbone, ... JBIC Journal of Biological Inorganic Chemistry 21, 1009-1020, 2016 | 59 | 2016 |
| Synthesis, crystal structure and cytotoxicity assays of a copper (II) nitrate complex with a tridentate ONO acylhydrazone ligand. Spectroscopic and theoretical studies of the … Y Burgos-Lopez, J Del Plá, LM Balsa, IE León, GA Echeverría, OE Piro, ... Inorganica Chimica Acta 487, 31-40, 2019 | 56 | 2019 |
| Polyoxometalates as antitumor agents: bioactivity of a new polyoxometalate with copper on a human osteosarcoma model IE Leon, V Porro, S Astrada, MG Egusquiza, CI Cabello, M Bollati-Fogolin, ... Chemico-biological interactions 222, 87-96, 2014 | 56 | 2014 |
| Anticancer and antimetastatic activity of copper (II)-tropolone complex against human breast cancer cells, breast multicellular spheroids and mammospheres LM Balsa, MC Ruiz, LSM de la Parra, EJ Baran, IE León Journal of Inorganic Biochemistry 204, 110975, 2020 | 54 | 2020 |
| Mononuclear Pd (ii) and Pt (ii) complexes with an α-N-heterocyclic thiosemicarbazone: cytotoxicity, solution behaviour and interaction versus proven models from biological media AI Matesanz, E Jimenez-Faraco, MC Ruiz, LM Balsa, ... Inorganic Chemistry Frontiers 5 (1), 73-83, 2018 | 53 | 2018 |
| Synthesis and biological characterization of organoruthenium complexes with 8-hydroxyquinolines J Kljun, IE León, Š Peršič, JF Cadavid-Vargas, SB Etcheverry, W He, ... Journal of Inorganic Biochemistry 186, 187-196, 2018 | 50 | 2018 |
| Comparative antitumor studies of organoruthenium complexes with 8-hydroxyquinolines on 2D and 3D cell models of bone, lung and breast cancer MC Ruiz, J Kljun, I Turel, AL Di Virgilio, IE León Metallomics 11 (3), 666-675, 2019 | 47 | 2019 |
| Deciphering the effect of an oxovanadium(iv) complex with the flavonoid chrysin (VOChrys) on intracellular cell signalling pathways in an osteosarcoma cell line IE León, P Díez, SB Etcheverry, M Fuentes Metallomics 8 (8), 739-749, 2016 | 47 | 2016 |
| Copper complexes as antitumor agents: In vitro and in vivo evidence LM Balsa, EJ Baran, IE León Current medicinal chemistry 30 (5), 510-557, 2023 | 43 | 2023 |
| Anticancer activity of a new copper (ii) complex with a hydrazone ligand. Structural and spectroscopic characterization, computational simulations and cell mechanistic studies … LM Balsa, V Ferraresi-Curotto, MJ Lavecchia, GA Echeverría, OE Piro, ... Dalton Transactions 50 (28), 9812-9826, 2021 | 40 | 2021 |
| Tetracycline-resistance encoding plasmids from Paenibacillus larvae, the causal agent of American foulbrood disease, isolated from commercial honeys AM Alippi, IE Leon, AC López Viguera Editores, 2014 | 39 | 2014 |
| Lipid, polymeric, inorganic-based drug delivery applications for platinum-based anticancer drugs T Boztepe, GR Castro, IE León International journal of pharmaceutics 605, 120788, 2021 | 37 | 2021 |
| An overview of vanadium and cell signaling in potential cancer treatments VA Ferretti, IE León Inorganics 10 (4), 47, 2022 | 33 | 2022 |
