Gonzalo Hortelano
Gonzalo Hortelano
Nazarbayev University, Kazakhstan; McMaster University, Canada
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Cell encapsulation: promise and progress
G Orive, RM Hernández, AR Gascón, R Calafiore, TMS Chang, PD Vos, ...
Nature medicine 9 (1), 104-107, 2003
History, challenges and perspectives of cell microencapsulation
G Orive, RM Hernandez, AR Gascon, R Calafiore, TMS Chang, P De Vos, ...
TRENDS in Biotechnology 22 (2), 87-92, 2004
Delivery of human factor IX in mice by encapsulated recombinant myoblasts: a novel approach towards allogeneic gene therapy of hemophilia B
G Hortelano, A Al-Hendy, FA Ofosu, PL Chang
Encapsulation of various recombinant mammalian cell types in different alginate microcapsules
M Peirone, CJD Ross, G Hortelano, JL Brash, PL Chang
Journal of Biomedical Materials Research: An Official Journal of The Society …, 1998
Correction of the growth defect in dwarf mice with nonautologous microencapsulated myoblasts—an alternate approach to somatic gene therapy
A Al-Hendy, G Hortelano, GS Tannenbaum, PL Chang
Human Gene Therapy 6 (2), 165-175, 1995
The in vivo delivery of heterologous proteins by microencapsulated recombinant cells
PL Chang, JM Van Raamsdonk, G Hortelano, SC Barsoum, ...
Trends in Biotechnology 17 (2), 78-83, 1999
Cell encapsulation within alginate microcapsules: immunological challenges and outlook
A Ashimova, S Yegorov, B Negmetzhanov, G Hortelano
Frontiers in Bioengineering and Biotechnology 7, 380, 2019
Growth of recombinant fibroblasts in alginate microcapsules
PL Chang, G Hortelano, DE Awrey, M Tse
Biotechnology and bioengineering 43 (10), 925-933, 1994
Induction of angiogenesis by implantation of encapsulated primary myoblasts expressing vascular endothelial growth factor
ML Springer, G Hortelano, DM Bouley, J Wong, PE Kraft, HM Blau
The journal of gene medicine 2 (4), 279-288, 2000
Permeability of alginate microcapsules to secretory recombinant gene products
DE Awrey, M Tse, G Hortelano, PL Chang
Biotechnology and Bioengineering 52 (4), 472-484, 1996
Effects of genetic fusion of factor IX to albumin on in vivo clearance in mice and rabbits
WP Sheffield, A Mamdani, G Hortelano, S Gataiance, L Eltringham‐Smith, ...
British journal of haematology 126 (4), 565-573, 2004
Delivery of a secretable adenosine deaminase through microcapsules–a novel approach to somatic gene therapy
M Hughes, A Vassilakos, DW Andrews, G Hortelano, JW Belmont, ...
Human Gene Therapy 5 (12), 1445-1455, 1994
Persistent delivery of factor IX in mice: gene therapy for hemophilia using implantable microcapsules
G Hortelano, N Xu, A Vandenberg, J Solera, PL Chang, FA Ofosu
Human gene therapy 10 (8), 1281-1288, 1999
Strategies for ocular siRNA delivery: Potential and limitations of non-viral nanocarriers
A Thakur, S Fitzpatrick, A Zaman, K Kugathasan, B Muirhead, G Hortelano, ...
Journal of biological engineering 6, 1-16, 2012
Therapeutic levels of human factor VIII in mice implanted with encapsulated cells: potential for gene therapy of haemophilia A
C García‐Martín, MKL Chuah, A Van Damme, KE Robinson, ...
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2002
Factors that contribute to the immmunogenicity of therapeutic recombinant human proteins
I Mukovozov, T Sabljic, G Hortelano, FA Ofosu
Thrombosis and haemostasis 99 (11), 874-882, 2008
Reduction of GAG storage in MPS II mouse model following implantation of encapsulated recombinant myoblasts
A Friso, R Tomanin, S Alba, N Gasparotto, EP Puicher, M Fusco, ...
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2005
Repeated oral administration of chitosan/DNA nanoparticles delivers functional FVIII with the absence of antibodies in hemophilia A mice
SS Dhadwar, J Kiernan, J Wen, G Hortelano
Journal of Thrombosis and Haemostasis 8 (12), 2743-2750, 2010
Sustained and therapeutic delivery of factor IX in nude haemophilia B mice by encapsulated C2C12 myoblasts: concurrent tumourigenesis
G Hortelano, L Wang, N Xu, FA Ofosu
Haemophilia 7 (2), 207-214, 2001
Growth retardation—an unexpected outcome from growth hormone gene therapy in normal mice with microencapsulated myoblasts
A Al-Hendy, G Hortelano, GS Tannenbaum, PL Chang
Human Gene Therapy 7 (1), 61-70, 1996
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