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Aslan Mansurov
Aslan Mansurov
Verified email at gilead.com
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Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours
A Mansurov, J Ishihara, P Hosseinchi, L Potin, TM Marchell, A Ishihara, ...
Nature biomedical engineering 4 (5), 531-543, 2020
1572020
Targeted antibody and cytokine cancer immunotherapies through collagen affinity
J Ishihara, A Ishihara, K Sasaki, SSY Lee, JM Williford, M Yasui, H Abe, ...
Science translational medicine 11 (487), eaau3259, 2019
1542019
Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy
JM Williford, J Ishihara, A Ishihara, A Mansurov, P Hosseinchi, ...
Science advances 5 (12), eaay1357, 2019
1072019
Engineered collagen-binding serum albumin as a drug conjugate carrier for cancer therapy
K Sasaki, J Ishihara, A Ishihara, R Miura, A Mansurov, K Fukunaga, ...
Science advances 5 (8), eaaw6081, 2019
742019
Bacterial adhesion to ultrafiltration membranes: role of hydrophilicity, natural organic matter, and cell-surface macromolecules
S BinAhmed, A Hasane, Z Wang, A Mansurov, ...
Environmental science & technology 52 (1), 162-172, 2018
732018
Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies
K Katsumata, J Ishihara, A Mansurov, A Ishihara, MM Raczy, E Yuba, ...
Science advances 5 (11), eaay1971, 2019
552019
Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker
A Mansurov, P Hosseinchi, K Chang, AL Lauterbach, LT Gray, AT Alpar, ...
Nature Biomedical Engineering 6 (7), 819-829, 2022
412022
Prolonged residence of an albumin–IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis
A Ishihara, J Ishihara, EA Watkins, AC Tremain, M Nguyen, A Solanki, ...
Nature Biomedical Engineering 5 (5), 387-398, 2021
292021
Polymersomes decorated with the SARS-CoV-2 spike protein receptor-binding domain elicit robust humoral and cellular immunity
LR Volpatti, RP Wallace, S Cao, MM Raczy, R Wang, LT Gray, AT Alpar, ...
ACS central science 7 (8), 1368-1380, 2021
282021
Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant
LT Gray, MM Raczy, PS Briquez, TM Marchell, AT Alpar, RP Wallace, ...
Biomaterials 278, 121159, 2021
222021
Immunoengineering approaches for cytokine therapy
A Mansurov, A Lauterbach, E Budina, AT Alpar, JA Hubbell, J Ishihara
American Journal of Physiology-Cell Physiology 321 (2), C369-C383, 2021
212021
Suppression of rheumatoid arthritis by enhanced lymph node trafficking of engineered interleukin‐10 in murine models
E Yuba, E Budina, K Katsumata, A Ishihara, A Mansurov, AT Alpar, ...
Arthritis & Rheumatology 73 (5), 769-778, 2021
182021
Tumor cell-surface binding of immune stimulating polymeric glyco-adjuvant via cysteine-reactive pyridyl disulfide promotes antitumor immunity
AJ Slezak, A Mansurov, MM Raczy, K Chang, AT Alpar, AL Lauterbach, ...
ACS Central Science 8 (10), 1435-1446, 2022
142022
Enhanced lymph node trafficking of engineered IL-10 suppresses rheumatoid arthritis in murine models
E Yuba, E Budina, K Katsumata, A Ishihara, A Mansurov, AT Alpar, ...
Arthritis & Rheumatology 73, 769, 2021
22021
Prolonged residence of an albumin-IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis (Oct, 10.1038/s41551-020-00627-3, 2020)
A Ishihara, J Ishihara, EA Watkins, AC Tremain, M Nguyen, A Solanki, ...
NATURE BIOMEDICAL ENGINEERING 4 (11), 1117-1117, 2020
22020
Therapeutic synthetic and natural materials for immunoengineering
A Slezak, K Chang, S Hossainy, A Mansurov, SJ Rowan, JA Hubbell, ...
Chemical Society Reviews, 2024
12024
Methods and compositions for treating inflammatory and autoimmune conditions with ecm-affinity peptides linked to anti-inflammatory agents
JA Hubbell, K Katsumata, A Ishihara, J Ishihara, A Mansurov
12020
Development and validation of a novel organotypic in vitro model of the tumor-lymph-immune interface for predicting immunotherapy resistance
R Zhou, R Weathered, T Kurtanich, R Mezyk-Kopec, A Mansurov, ...
CANCER RESEARCH 80 (11), 68-68, 2020
12020
Matrix-binding IL-12 enhances tumor inflammation and drives complete remission in established cold murine tumors
A Mansurov, J Hubbell, J Ishihara
Journal For Immunotherapy of Cancer 7, 2019
12019
Cysteine-binding adjuvant enhances survival and promotes immune function in a murine model of acute myeloid leukemia
AJ Slezak, K Chang, TN Beckman, KC Refvik, AT Alpar, AL Lauterbach, ...
Blood Advances, bloodadvances. 2023012529, 2024
2024
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