Richard Fishel
Richard Fishel
The Ohio State University Wexner Medical Center
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The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
R Fishel, MK Lescoe, MRS Rao, NG Copeland, NA Jenkins, J Garber, ...
Cell 75 (5), 1027-1038, 1993
Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability
A Umar, CR Boland, JP Terdiman, S Syngal, A Chapelle, J Rüschoff, ...
Journal of the National Cancer Institute 96 (4), 261-268, 2004
Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer
CE Bronner, SM Baker, PT Morrison, G Warren, LG Smith, MK Lescoe, ...
Nature 368 (6468), 258-261, 1994
Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression
W Dietmaier, S Wallinger, T Bocker, F Kullmann, R Fishel, J Rüschoff
Cancer research 57 (21), 4749-4756, 1997
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6
S Acharya, T Wilson, S Gradia, MF Kane, S Guerrette, GT Marsischky, ...
Proceedings of the National Academy of Sciences 93 (24), 13629-13634, 1996
Loss of DNA mismatch repair in acquired resistance to cisplatin
S Aebi, B Kurdi-Haidar, R Gordon, B Cenni, H Zheng, D Fink, RD Christen, ...
Cancer research 56 (13), 3087-3090, 1996
Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
A Saleh, SM Srinivasula, S Acharya, R Fishel, ES Alnemri
Journal of Biological Chemistry 274 (25), 17941-17945, 1999
hMSH4-hMSH5 recognizes Holliday Junctions and forms a meiosis-specific sliding clamp that embraces homologous chromosomes
T Snowden, S Acharya, C Butz, M Berardini, R Fishel
Molecular cell 15 (3), 437-451, 2004
MSH2 deficient mice are viable and susceptible to lymphoid tumours
AH Reitmair, R Schmits, A Ewel, B Bapat, M Redston, A Mitri, ...
Nature genetics 11 (1), 64-70, 1995
hMSH2–hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA
S Gradia, D Subramanian, T Wilson, S Acharya, A Makhov, J Griffith, ...
Molecular cell 3 (2), 255-261, 1999
Modulation of mismatch repair and genomic stability by miR-155
N Valeri, P Gasparini, M Fabbri, C Braconi, A Veronese, F Lovat, B Adair, ...
Proceedings of the National Academy of Sciences 107 (15), 6982-6987, 2010
The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch
S Gradia, S Acharya, R Fishel
Cell 91 (7), 995-1005, 1997
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics
T Ikura, S Tashiro, A Kakino, H Shima, N Jacob, R Amunugama, K Yoder, ...
Molecular and cellular biology 27 (20), 7028-7040, 2007
Identification of mismatch repair genes and their role in the development of cancer
R Fishel, RD Kolodner
Current opinion in genetics & development 5 (3), 382-395, 1995
MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2)
N Valeri, P Gasparini, C Braconi, A Paone, F Lovat, M Fabbri, KM Sumani, ...
Proceedings of the National Academy of Sciences 107 (49), 21098-21103, 2010
BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance
A Slupianek, C Schmutte, G Tombline, M Nieborowska-Skorska, G Hoser, ...
Molecular cell 8 (4), 795-806, 2001
The coordinated functions of the E. coli MutS and MutL proteins in mismatch repair
S Acharya, PL Foster, P Brooks, R Fishel
Molecular cell 12 (1), 233-246, 2003
MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers
SB Simpkins, T Bocker, EM Swisher, DG Mutch, DJ Gersell, AJ Kovatich, ...
Human molecular genetics 8 (4), 661-666, 1999
Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors
Y Xie, H Yang, C Cunanan, K Okamoto, D Shibata, J Pan, DE Barnes, ...
Cancer research 64 (9), 3096-3102, 2004
Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum
JR Jass, H Iino, A Ruszkiewicz, D Painter, MJ Solomon, DJ Koorey, ...
Gut 47 (1), 43-49, 2000
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