Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability A Umar, CR Boland, JP Terdiman, S Syngal, A Chapelle, J Rüschoff, ... Journal of the National Cancer Institute 96 (4), 261-268, 2004 | 3937 | 2004 |
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer R Fishel, MK Lescoe, MRS Rao, NG Copeland, NA Jenkins, J Garber, ... Cell 75 (5), 1027-1038, 1993 | 3839 | 1993 |
Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer CE Bronner, SM Baker, PT Morrison, G Warren, LG Smith, MK Lescoe, ... Nature 368 (6468), 258-261, 1994 | 2805 | 1994 |
Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression W Dietmaier, S Wallinger, T Bocker, F Kullmann, R Fishel, J Rüschoff Cancer research 57 (21), 4749-4756, 1997 | 958 | 1997 |
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6 S Acharya, T Wilson, S Gradia, MF Kane, S Guerrette, GT Marsischky, ... Proceedings of the National Academy of Sciences 93 (24), 13629-13634, 1996 | 756 | 1996 |
Loss of DNA mismatch repair in acquired resistance to cisplatin S Aebi, B Kurdi-Haidar, R Gordon, B Cenni, H Zheng, D Fink, RD Christen, ... Cancer research 56 (13), 3087-3090, 1996 | 715 | 1996 |
Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation A Saleh, SM Srinivasula, S Acharya, R Fishel, ES Alnemri Journal of Biological Chemistry 274 (25), 17941-17945, 1999 | 702 | 1999 |
hMSH4-hMSH5 recognizes Holliday Junctions and forms a meiosis-specific sliding clamp that embraces homologous chromosomes T Snowden, S Acharya, C Butz, M Berardini, R Fishel Molecular cell 15 (3), 437-451, 2004 | 487 | 2004 |
MSH2 deficient mice are viable and susceptible to lymphoid tumours AH Reitmair, R Schmits, A Ewel, B Bapat, M Redston, A Mitri, ... Nature genetics 11 (1), 64-70, 1995 | 465 | 1995 |
hMSH2–hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA S Gradia, D Subramanian, T Wilson, S Acharya, A Makhov, J Griffith, ... Molecular cell 3 (2), 255-261, 1999 | 457 | 1999 |
Modulation of mismatch repair and genomic stability by miR-155 N Valeri, P Gasparini, M Fabbri, C Braconi, A Veronese, F Lovat, B Adair, ... Proceedings of the National Academy of Sciences 107 (15), 6982-6987, 2010 | 453 | 2010 |
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics T Ikura, S Tashiro, A Kakino, H Shima, N Jacob, R Amunugama, K Yoder, ... Molecular and cellular biology, 2007 | 451 | 2007 |
The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch S Gradia, S Acharya, R Fishel Cell 91 (7), 995-1005, 1997 | 447 | 1997 |
MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2) N Valeri, P Gasparini, C Braconi, A Paone, F Lovat, M Fabbri, KM Sumani, ... Proceedings of the National Academy of Sciences 107 (49), 21098-21103, 2010 | 446 | 2010 |
Identification of mismatch repair genes and their role in the development of cancer R Fishel, RD Kolodner Current opinion in genetics & development 5 (3), 382-395, 1995 | 436 | 1995 |
BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance A Slupianek, C Schmutte, G Tombline, M Nieborowska-Skorska, G Hoser, ... Molecular cell 8 (4), 795-806, 2001 | 398 | 2001 |
MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers SB Simpkins, T Bocker, EM Swisher, DG Mutch, DJ Gersell, AJ Kovatich, ... Human molecular genetics 8 (4), 661-666, 1999 | 391 | 1999 |
The coordinated functions of the E. coli MutS and MutL proteins in mismatch repair S Acharya, PL Foster, P Brooks, R Fishel Molecular cell 12 (1), 233-246, 2003 | 388 | 2003 |
Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors Y Xie, H Yang, C Cunanan, K Okamoto, D Shibata, J Pan, DE Barnes, ... Cancer research 64 (9), 3096-3102, 2004 | 348 | 2004 |
Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum JR Jass, H Iino, A Ruszkiewicz, D Painter, MJ Solomon, DJ Koorey, ... Gut 47 (1), 43-49, 2000 | 308 | 2000 |