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Alain de Bruin
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An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA
M Demaria, N Ohtani, SA Youssef, F Rodier, W Toussaint, JR Mitchell, ...
Developmental cell 31 (6), 722-733, 2014
18142014
Cellular senescence promotes adverse effects of chemotherapy and cancer relapse
M Demaria, MN O'Leary, J Chang, L Shao, SU Liu, F Alimirah, K Koenig, ...
Cancer discovery 7 (2), 165-176, 2017
11502017
Direct evidence for epithelial-mesenchymal transitions in breast cancer
AJ Trimboli, K Fukino, A De Bruin, G Wei, L Shen, SM Tanner, N Creasap, ...
Cancer research 68 (3), 937-945, 2008
4852008
Extra-embryonic function of Rb is essential for embryonic development and viability
L Wu, A De Bruin, HI Saavedra, M Starovic, A Trimboli, Y Yang, J Opavska, ...
Nature 421 (6926), 942-947, 2003
4442003
MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling
PA da Costa Martins, K Salic, MM Gladka, AS Armand, S Leptidis, ...
Nature cell biology 12 (12), 1220-1227, 2010
3992010
Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation
A De Bruin, B Maiti, L Jakoi, C Timmers, R Buerki, G Leone
Journal of Biological Chemistry 278 (43), 42041-42049, 2003
3102003
High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice
RA van der Heijden, F Sheedfar, MC Morrison, PPH Hommelberg, D Kor, ...
Aging (Albany NY) 7 (4), 256, 2015
2942015
A proinflammatory gut microbiota increases systemic inflammation and accelerates atherosclerosis
E Brandsma, NJ Kloosterhuis, M Koster, DC Dekker, MJJ Gijbels, ...
Circulation research 124 (1), 94-100, 2019
2822019
Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice
WP Vermeij, MET Dollé, E Reiling, D Jaarsma, C Payan-Gomez, ...
Nature 537 (7620), 427-431, 2016
2812016
In vivo biocompatibility and biodegradation of 3D-printed porous scaffolds based on a hydroxyl-functionalized poly (ε-caprolactone)
H Seyednejad, D Gawlitta, RV Kuiper, A de Bruin, CF van Nostrum, ...
Biomaterials 33 (17), 4309-4318, 2012
2742012
Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development
J Li, C Ran, E Li, F Gordon, G Comstock, H Siddiqui, W Cleghorn, ...
Developmental cell 14 (1), 62-75, 2008
2672008
Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation
B Maiti, J Li, A De Bruin, F Gordon, C Timmers, R Opavsky, K Patil, J Tuttle, ...
Journal of Biological Chemistry 280 (18), 18211-18220, 2005
2562005
A central role for the armadillo protein plakoglobin in the autoimmune disease pemphigus vulgaris
R Caldelari, A de Bruin, D Baumann, MM Suter, C Bierkamp, V Balmer, ...
The Journal of cell biology 153 (4), 823-834, 2001
2262001
Pemphigus vulgaris identifies plakoglobin as key suppressor of c‐Myc in the skin
L Williamson, NA Raess, R Caldelari, A Zakher, A de Bruin, H Posthaus, ...
The EMBO journal 25 (14), 3298-3309, 2006
2042006
Physiological significance of polyploidization in mammalian cells
SK Pandit, B Westendorp, A de Bruin
Trends in cell biology 23 (11), 556-566, 2013
1802013
E2F8 is essential for polyploidization in mammalian cells
SK Pandit, B Westendorp, S Nantasanti, E Van Liere, PCJ Tooten, ...
Nature cell biology 14 (11), 1181-1191, 2012
1672012
Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice
A De Bruin, L Wu, HI Saavedra, P Wilson, Y Yang, TJ Rosol, M Weinstein, ...
Proceedings of the National Academy of Sciences 100 (11), 6546-6551, 2003
1672003
Essential role for survivin in early brain development
Y Jiang, A De Bruin, H Caldas, J Fangusaro, J Hayes, EM Conway, ...
Journal of Neuroscience 25 (30), 6962-6970, 2005
1542005
Full ablation of C9orf72 in mice causes immune system-related pathology and neoplastic events but no motor neuron defects
E Sudria-Lopez, M Koppers, M de Wit, C van der Meer, HJ Westeneng, ...
Acta neuropathologica 132, 145-147, 2016
1492016
E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1
BGMW Weijts, WJ Bakker, PWA Cornelissen, KH Liang, FH Schaftenaar, ...
The EMBO journal 31 (19), 3871-3884, 2012
1412012
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