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Mette Skinbjerg
Mette Skinbjerg
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D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: a PET study in a receptor internalization-deficient mouse model
M Skinbjerg, JS Liow, N Seneca, J Hong, S Lu, A Thorsell, M Heilig, ...
Neuroimage 50 (4), 1402-1407, 2010
892010
The dopamine dysfunction in schizophrenia revisited: new insights into topography and course
R Kuepper, M Skinbjerg, A Abi-Dargham
Current antipsychotics, 1-26, 2012
782012
Imaging changes in glutamate transmission in vivo with the metabotropic glutamate receptor 5 tracer [11C] ABP688 and N-acetylcysteine challenge
N Miyake, M Skinbjerg, B Easwaramoorthy, D Kumar, RR Girgis, X Xu, ...
Biological psychiatry 69 (9), 822-824, 2011
742011
Imaging the high-affinity state of the dopamine D2 receptor in vivo: fact or fiction?
M Skinbjerg, DR Sibley, JA Javitch, A Abi-Dargham
Biochemical pharmacology 83 (2), 193-198, 2012
712012
Presynaptic dopamine in schizophrenia
N Miyake, J Thompson, M Skinbjerg, A Abi‐Dargham
CNS neuroscience & therapeutics 17 (2), 104-109, 2011
712011
Reciprocal modulation of function between the D1 and D2 dopamine receptors and the Na+, K+-ATPase
LA Hazelwood, RB Free, DM Cabrera, M Skinbjerg, DR Sibley
Journal of Biological Chemistry 283 (52), 36441-36453, 2008
652008
Validation and noninvasive kinetic modeling of [11C]UCB-J PET imaging in mice
D Bertoglio, J Verhaeghe, A Miranda, I Kertesz, K Cybulska, Š Korat, ...
Journal of Cerebral Blood Flow & Metabolism 40 (6), 1351-1362, 2020
452020
Pharmacological characterization of 2‐methoxy‐N‐propylnorapomorphine's interactions with D2 and D3 dopamine receptors
M Skinbjerg, Y Namkung, C Halldin, RB Innis, DR Sibley
Synapse 63 (6), 462-475, 2009
422009
Arrestin3 mediates D2 dopamine receptor internalization
M Skinbjerg, MA Ariano, A Thorsell, M Heilig, C Halldin, RB Innis, ...
Synapse (New York, NY) 63 (7), 621, 2009
412009
Occupancy of dopamine D2/3 receptors in rat brain by endogenous dopamine measured with the agonist positron emission tomography radioligand [11C]MNPA
N Seneca, SS Zoghbi, M Skinbjerg, JS Liow, J Hong, DR Sibley, VW Pike, ...
Synapse 62 (10), 756-763, 2008
352008
Dopamine β‐hydroxylase‐deficient mice have normal densities of D2 dopamine receptors in the high‐affinity state based on in vivo PET imaging and in vitro …
M Skinbjerg, N Seneca, JS Liow, J Hong, D Weinshenker, VW Pike, ...
Synapse 64 (9), 699-703, 2010
232010
Development of a ligand for in vivo imaging of mutant huntingtin in Huntington’s disease
D Bertoglio, J Bard, M Hessmann, L Liu, A Gärtner, S De Lombaerde, ...
Science translational medicine 14 (630), eabm3682, 2022
212022
Kinetic brain analysis and whole‐body imaging in monkey of [11C]MNPA: A dopamine agonist radioligand
N Seneca, M Skinbjerg, SS Zoghbi, JS Liow, RL Gladding, J Hong, ...
Synapse 62 (9), 700-709, 2008
182008
In vitro and In vivo Assessment of Suitable Reference Region and Kinetic Modelling for the mGluR1 Radioligand [11C]ITDM in Mice
D Bertoglio, J Verhaeghe, Š Korat, A Miranda, L Wyffels, S Stroobants, ...
Molecular Imaging and Biology 22, 854-863, 2020
152020
Synaptic vesicle glycoprotein 2A is affected in the CNS of Huntington’s disease mice and post-mortem human HD brain
D Bertoglio, J Verhaeghe, A Miranda, S Stroobants, L Mrzljak, ...
Journal of Nuclear Medicine, 2021
142021
Longitudinal preclinical evaluation of the novel radioligand [11C] CHDI-626 for PET imaging of mutant huntingtin aggregates in Huntington’s disease
D Bertoglio, J Verhaeghe, A Miranda, L Wyffels, S Stroobants, L Mrzljak, ...
European Journal of Nuclear Medicine and Molecular Imaging, 1-10, 2022
122022
Synaptic vesicle glycoprotein 2A is affected in the central nervous system of mice with huntington disease and in the brain of a human with huntington disease postmortem
D Bertoglio, J Verhaeghe, L Wyffels, A Miranda, S Stroobants, L Mrzljak, ...
Journal of Nuclear Medicine 63 (6), 942-947, 2022
102022
Biodistribution and dosimetry in human healthy volunteers of the PET radioligands [11C]CHDI-00485180-R and [11C]CHDI-00485626, designed for quantification …
A Delva, M Koole, K Serdons, G Bormans, L Liu, J Bard, V Khetarpal, ...
European journal of nuclear medicine and molecular imaging 50 (1), 48-60, 2022
62022
Elevated type 1 metabotropic glutamate receptor availability in a mouse model of Huntington’s disease: a longitudinal PET study
D Bertoglio, J Verhaeghe, Š Korat, A Miranda, K Cybulska, L Wyffels, ...
Molecular neurobiology 57, 2038-2047, 2020
62020
Kinetic Modelling and Test–Retest Reproducibility for the Dopamine D1R Radioligand [11C]SCH23390 in Healthy and Diseased Mice
D Bertoglio, J Verhaeghe, A Miranda, L Wyffels, S Stroobants, ...
Molecular Imaging and Biology 23, 208-219, 2021
52021
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