Convergent evolution of caffeine in plants by co-option of exapted ancestral enzymes R Huang, AJ O’Donnell, JJ Barboline, TJ Barkman Proceedings of the National Academy of Sciences 113 (38), 10613-10618, 2016 | 124 | 2016 |
Enzyme functional evolution through improved catalysis of ancestrally nonpreferred substrates R Huang, F Hippauf, D Rohrbeck, M Haustein, K Wenke, J Feike, ... Proceedings of the National Academy of Sciences 109 (8), 2966-2971, 2012 | 107 | 2012 |
Diversity in the cow ultralong CDR H3 antibody repertoire JK Haakenson, R Huang, VV Smider Frontiers in immunology 9, 380945, 2018 | 43 | 2018 |
Enzymatic, expression and structural divergences among carboxyl O-methyltransferases after gene duplication and speciation in Nicotiana F Hippauf, E Michalsky, R Huang, R Preissner, TJ Barkman, B Piechulla Plant molecular biology 72, 311-330, 2010 | 37 | 2010 |
Structures of the T cell potassium channel Kv1. 3 with immunoglobulin modulators P Selvakumar, AI Fernández-Mariño, N Khanra, C He, AJ Paquette, ... Nature Communications 13 (1), 3854, 2022 | 34 | 2022 |
Structural basis of broad HIV neutralization by a vaccine-induced cow antibody RL Stanfield, ZT Berndsen, R Huang, D Sok, G Warner, JL Torres, ... Science advances 6 (22), eaba0468, 2020 | 34 | 2020 |
Diversity of ACE2 and its interaction with SARS-CoV-2 receptor binding domain J Low-Gan, R Huang, A Kelley, GW Jenkins, D McGregor, VV Smider Biochemical Journal 478 (19), 3671-3684, 2021 | 17 | 2021 |
Convergent biochemical pathways for xanthine alkaloid production in plants evolved from ancestral enzymes with different catalytic properties AJ O’Donnell, R Huang, JJ Barboline, TJ Barkman Molecular Biology and Evolution 38 (7), 2704-2714, 2021 | 7 | 2021 |
The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2 R Huang, G Warner Jenkins, Y Kim, RL Stanfield, A Singh, ... Proceedings of the National Academy of Sciences 120 (39), e2303455120, 2023 | 4 | 2023 |
A collaborative classroom investigation of the evolution of SABATH methyltransferase substrate preference shifts over 120 My of flowering plant history NM Dubs, BR Davis, V de Brito, KC Colebrook, IJ Tiefel, MB Nakayama, ... Molecular Biology and Evolution 39 (3), msac007, 2022 | 4 | 2022 |
Evolution of Caffeine Biosynthetic Enzymes and Pathways in Flowering Plants R Huang Western Michigan University, 2017 | 3 | 2017 |
Evolution of immunogenetic components encoding ultralong CDR H3 JA Ott, C Mitchell, M Sheppard, TC Deiss, JMC Horton, JK Haakenson, ... Immunogenetics 75 (4), 323-339, 2023 | 2 | 2023 |
Studies on enzyme functional evolution in the SABATH multigene family using phylogenetic and biochemical approaches R Huang | 1 | 2012 |
Ultralong CDR3 engineered interleukin-15 antibody fusion for T and NK cell expansion R Huang, D McGregor, V Smider Cancer Research 84 (6_Supplement), 5811-5811, 2024 | | 2024 |
Chimeric cytokine modified antibodies and methods of use thereof R Huang, V Smider US Patent App. 17/770,986, 2022 | | 2022 |
Chimeric cytokine modified antibodies and methods of use thereof R HUANG, V Smider | | 2021 |