Matteo Ruggiu, PhD
Matteo Ruggiu, PhD
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CLIP identifies Nova-regulated RNA networks in the brain
J Ule, KB Jensen, M Ruggiu, A Mele, A Ule, RB Darnell
Science 302 (5648), 1212-1215, 2003
The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis
M Ruggiu, R Speed, M Taggart, SJ McKay, F Kilanowski, P Saunders, ...
Nature 389 (6646), 73-77, 1997
An RNA map predicting Nova-dependent splicing regulation
J Ule, G Stefani, A Mele, M Ruggiu, X Wang, B Taneri, T Gaasterland, ...
Nature 444 (7119), 580-586, 2006
Nova regulates brain-specific splicing to shape the synapse
J Ule, A Ule, J Spencer, A Williams, JS Hu, M Cline, H Wang, T Clark, ...
Nature genetics 37 (8), 844-852, 2005
Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls
C Zhang, MA Frias, A Mele, M Ruggiu, T Eom, CB Marney, H Wang, ...
Science 329 (5990), 439-443, 2010
A murine homologue of the human DAZ gene is autosomal and expressed only in male and female gonads
HJ Cooke, M Lee, S Kerr, M Ruggiu
Human Molecular Genetics 5 (4), 513-516, 1996
Absence of mDazl produces a final block on germ cell development at meiosis
PTK Saunders, JMA Turner, M Ruggiu, M Taggart, PS Burgoyne, D Elliott, ...
REPRODUCTION-CAMBRIDGE- 126 (5), 589-597, 2003
Common molecular pathways mediate long-term potentiation of synaptic excitation and slow synaptic inhibition
CS Huang, SH Shi, J Ule, M Ruggiu, LA Barker, RB Darnell, YN Jan, ...
Cell 123 (1), 105-118, 2005
A role for SMN exon 7 splicing in the selective vulnerability of motor neurons in spinal muscular atrophy
M Ruggiu, VL McGovern, F Lotti, L Saieva, DK Li, S Kariya, UR Monani, ...
Molecular and cellular biology, 2011
Rescuing Z+ agrin splicing in Nova null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing
M Ruggiu, R Herbst, N Kim, M Jevsek, JJ Fak, MA Mann, G Fischbach, ...
Proceedings of the National Academy of Sciences 106 (9), 3513-3518, 2009
Alternative splicing microarrays reveal functional expression of neuron-specific regulators in Hodgkin lymphoma cells
A Relógio, C Ben-Dov, M Baum, M Ruggiu, C Gemund, V Benes, ...
Journal of Biological Chemistry 280 (6), 4779-4784, 2005
The RNA-binding specificity of the mouse Dazl protein
JP Venables, M Ruggiu, HJ Cooke
Nucleic acids research 29 (12), 2479-2483, 2001
NOVA2-mediated RNA regulation is required for axonal pathfinding during development
Y Saito, S Miranda-Rottmann, M Ruggiu, CY Park, JJ Fak, R Zhong, ...
Elife 5, e14371, 2016
Two homologous genes, originated by duplication, encode the human hnRNP proteins A2 and A1
G Biamonti, M Ruggiu, S Saccone, GD Valle, S Riva
Nucleic acids research 22 (11), 1996-2002, 1994
Dynamic subcellular distribution of the DAZL protein is confined to primate male germ cells
Journal of andrology 21 (3), 470-477, 2000
SLC25A10 biallelic mutations in intractable epileptic encephalopathy with complex I deficiency
G Punzi, V Porcelli, M Ruggiu, MF Hossain, A Menga, P Scarcia, ...
Human Molecular Genetics 27 (3), 499-504, 2018
In vivo and in vitro analysis of homodimerisation activity of the mouse Dazl1 protein
M Ruggiu, HJ Cooke
Gene 252 (1-2), 119-126, 2000
Splicing regulation of pro-inflammatory cytokines and chemokines: at the interface of the neuroendocrine and immune systems
F Shakola, P Suri, M Ruggiu
Biomolecules 5 (3), 2073-2100, 2015
Y bind RNA for spermatogenesis?
M Ruggiu, H Cooke
International journal of andrology (Print) 22 (1), 19-27, 1999
Radiolabeled semi-quantitative RT-PCR assay for the analysis of alternative splicing of interleukin genes
F Shakola, S Byrne, K Javed, M Ruggiu
Cytokine Bioassays: Methods and Protocols, 343-362, 2014
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