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Madeline Lancaster
Madeline Lancaster
MRC Laboratory of Molecular Biology
Dirección de correo verificada de mrc-lmb.cam.ac.uk - Página principal
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Cerebral organoids model human brain development and microcephaly
MA Lancaster, M Renner, CA Martin, D Wenzel, LS Bicknell, ME Hurles, ...
Nature 501 (7467), 373-379, 2013
47702013
Organogenesis in a dish: modeling development and disease using organoid technologies
MA Lancaster, JA Knoblich
Science 345 (6194), 1247125, 2014
26022014
Generation of cerebral organoids from human pluripotent stem cells
MA Lancaster, JA Knoblich
Nature protocols 9 (10), 2329-2340, 2014
14302014
Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
JG Camp, F Badsha, M Florio, S Kanton, T Gerber, M Wilsch-Bräuninger, ...
Proceedings of the National Academy of Sciences 112 (51), 15672-15677, 2015
10302015
Guided self-organization and cortical plate formation in human brain organoids
MA Lancaster, NS Corsini, S Wolfinger, EH Gustafson, AW Phillips, ...
Nature biotechnology 35 (7), 659-666, 2017
6862017
Mutations in CEP290, which encodes a centrosomal protein, cause pleiotropic forms of Joubert syndrome
EM Valente, JL Silhavy, F Brancati, G Barrano, SR Krishnaswami, ...
Nature genetics 38 (6), 623-625, 2006
5062006
SARS-CoV-2 infects the brain choroid plexus and disrupts the blood-CSF barrier in human brain organoids
L Pellegrini, A Albecka, DL Mallery, MJ Kellner, D Paul, AP Carter, ...
Cell stem cell 27 (6), 951-961. e5, 2020
4612020
Cerebral organoids at the air–liquid interface generate diverse nerve tracts with functional output
SL Giandomenico, SB Mierau, GM Gibbons, LMD Wenger, L Masullo, ...
Nature neuroscience 22 (4), 669-679, 2019
4392019
Induction of expansion and folding in human cerebral organoids
Y Li, J Muffat, A Omer, I Bosch, MA Lancaster, M Sur, L Gehrke, ...
Cell stem cell 20 (3), 385-396. e3, 2017
3982017
Stem cell models of human brain development
I Kelava, MA Lancaster
Cell stem cell 18 (6), 736-748, 2016
3642016
Self‐organized developmental patterning and differentiation in cerebral organoids
M Renner, MA Lancaster, S Bian, H Choi, T Ku, A Peer, K Chung, ...
The EMBO journal 36 (10), 1316-1329, 2017
3382017
Cerebral organoids recapitulate epigenomic signatures of the human fetal brain
C Luo, MA Lancaster, R Castanon, JR Nery, JA Knoblich, JR Ecker
Cell reports 17 (12), 3369-3384, 2016
3352016
Dishing out mini-brains: Current progress and future prospects in brain organoid research
I Kelava, MA Lancaster
Developmental biology 420 (2), 199-209, 2016
3162016
Disease modelling in human organoids
MA Lancaster, M Huch
Disease models & mechanisms 12 (7), dmm039347, 2019
3052019
Subcellular spatial regulation of canonical Wnt signalling at the primary cilium
MA Lancaster, J Schroth, JG Gleeson
Nature cell biology 13 (6), 700-707, 2011
2942011
Human CNS barrier-forming organoids with cerebrospinal fluid production
L Pellegrini, C Bonfio, J Chadwick, F Begum, M Skehel, MA Lancaster
Science 369 (6500), eaaz5626, 2020
2892020
Brain organoids for the study of human neurobiology at the interface of in vitro and in vivo
I Chiaradia, MA Lancaster
Nature Neuroscience 23 (12), 1496-1508, 2020
2162020
Non-model model organisms
JJ Russell, JA Theriot, P Sood, WF Marshall, LF Landweber, L Fritz-Laylin, ...
BMC biology 15, 1-31, 2017
2152017
Impaired Wnt–β-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy
MA Lancaster, CM Louie, JL Silhavy, L Sintasath, M DeCambre, ...
Nature medicine 15 (9), 1046-1054, 2009
2062009
AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis
CM Louie, G Caridi, VS Lopes, F Brancati, A Kispert, MA Lancaster, ...
Nature genetics 42 (2), 175-180, 2010
2032010
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