| Poly (ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia MJL Eliasson, K Sampei, AS Mandir, PD Hurn, RJ Traystman, J Bao, ... Nature medicine 3 (10), 1089-1095, 1997 | 1248 | 1997 |
| Poly (ADP-ribose) polymerase, nitric oxide and cell death AA Pieper, A Verma, J Zhang, SH Snyder Trends in pharmacological sciences 20 (4), 171-181, 1999 | 651 | 1999 |
| Poly (ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes AA Pieper, DJ Brat, DK Krug, CC Watkins, A Gupta, S Blackshaw, ... Proceedings of the National Academy of Sciences 96 (6), 3059-3064, 1999 | 399 | 1999 |
| Discovery of a proneurogenic, neuroprotective chemical AA Pieper, S Xie, E Capota, SJ Estill, J Zhong, JM Long, GL Becker, ... Cell 142 (1), 39-51, 2010 | 395 | 2010 |
| FGF21 mediates endocrine control of simple sugar intake and sweet taste preference by the liver S von Holstein-Rathlou, LD BonDurant, L Peltekian, MC Naber, TC Yin, ... Cell metabolism 23 (2), 335-343, 2016 | 313 | 2016 |
| A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome CM Buchovecky, SD Turley, HM Brown, SM Kyle, JG McDonald, B Liu, ... Nature genetics 45 (9), 1013-1020, 2013 | 223 | 2013 |
| P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage G Wang, T Han, D Nijhawan, P Theodoropoulos, J Naidoo, S Yadavalli, ... Cell 158 (6), 1324-1334, 2014 | 220 | 2014 |
| The neuronal PAS domain protein 3 transcription factor controls FGF-mediated adult hippocampal neurogenesis in mice AA Pieper, X Wu, TW Han, SJ Estill, Q Dang, LC Wu, S Reece-Fincanon, ... Proceedings of the National Academy of Sciences 102 (39), 14052-14057, 2005 | 207 | 2005 |
| Development of proneurogenic, neuroprotective small molecules KS MacMillan, J Naidoo, J Liang, L Melito, NS Williams, L Morlock, ... Journal of the American Chemical Society 133 (5), 1428-1437, 2011 | 200 | 2011 |
| Myocardial postischemic injury is reduced by polyADPribose polymerase-1 gene disruption AA Pieper, T Walles, G Wei, EE Clements, A Verma, SH Snyder, ... Molecular Medicine 6 (4), 271-282, 2000 | 200 | 2000 |
| Post-treatment with an inhibitor of poly (ADP-ribose) polymerase attenuates cerebral damage in focal ischemia K Takahashi, AA Pieper, SE Croul, J Zhang, SH Snyder, JH Greenberg Brain research 829 (1-2), 46-54, 1999 | 198 | 1999 |
| Unesterified cholesterol accumulation in late endosomes/lysosomes causes neurodegeneration and is prevented by driving cholesterol export from this compartment A Aqul, B Liu, CM Ramirez, AA Pieper, SJ Estill, DK Burns, B Liu, JJ Repa, ... Journal of neuroscience 31 (25), 9404-9413, 2011 | 181 | 2011 |
| Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis R Tesla, HP Wolf, P Xu, J Drawbridge, SJ Estill, P Huntington, ... Proceedings of the National Academy of Sciences 109 (42), 17016-17021, 2012 | 161 | 2012 |
| Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease H De Jesús-Cortés, P Xu, J Drawbridge, SJ Estill, P Huntington, S Tran, ... Proceedings of the National Academy of Sciences 109 (42), 17010-17015, 2012 | 155 | 2012 |
| The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis AK Walker, PD Rivera, Q Wang, JC Chuang, S Tran, ... Molecular psychiatry 20 (4), 500-508, 2015 | 154 | 2015 |
| Poly (ADP‐ribose) synthetase activation: an early indicator of neurotoxic DNA damage J Zhang, A Pieper, SH Snyder Journal of neurochemistry 65 (3), 1411-1414, 1995 | 150 | 1995 |
| Poly (ADP-ribosyl) ation basally activated by DNA strand breaks reflects glutamate–nitric oxide neurotransmission AA Pieper, S Blackshaw, EE Clements, DJ Brat, DK Krug, AJ White, ... Proceedings of the National Academy of Sciences 97 (4), 1845-1850, 2000 | 134 | 2000 |
| Wild-type microglia do not reverse pathology in mouse models of Rett syndrome J Wang, JE Wegener, TW Huang, S Sripathy, H De Jesus-Cortes, P Xu, ... Nature 521 (7552), E1-E4, 2015 | 119 | 2015 |
| P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury TC Yin, JK Britt, H De Jesús-Cortés, Y Lu, RM Genova, MZ Khan, ... Cell reports 8 (6), 1731-1740, 2014 | 113 | 2014 |
| Neurotoxicity in preclinical models of occupational exposure to organophosphorus compounds JR Voorhees, DS Rohlman, PJ Lein, AA Pieper Frontiers in neuroscience 10, 590, 2017 | 107 | 2017 |
Solomon H SnyderJohns HopkinsVerified email at jhmi.edu
