| Characterization of peptides bound to the class I MHC molecule HLA-A2. 1 by mass spectrometry DF Hunt, RA Henderson, J Shabanowitz, K Sakaguchi, H Michel, N Sevilir, ... Science 255 (5049), 1261-1263, 1992 | 1658 | 1992 |
| Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer B Chen, ME Dodge, W Tang, J Lu, Z Ma, CW Fan, S Wei, W Hao, J Kilgore, ... Nature chemical biology 5 (2), 100, 2009 | 1591 | 2009 |
| Targeting QseC signaling and virulence for antibiotic development DA Rasko, CG Moreira, NC Reading, JM Ritchie, MK Waldor, N Williams, ... Science 321 (5892), 1078-1080, 2008 | 575 | 2008 |
| Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15 T Han, M Goralski, N Gaskill, E Capota, J Kim, TC Ting, Y Xie, ... Science 356 (6336), eaal3755, 2017 | 494 | 2017 |
| Discovery of a proneurogenic, neuroprotective chemical AA Pieper, S Xie, E Capota, SJ Estill, J Zhong, JM Long, GL Becker, ... Cell 142 (1), 39-51, 2010 | 421 | 2010 |
| Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference NS Williams, RB Gaynor, S Scoggin, U Verma, T Gokaslan, C Simmang, ... Clinical Cancer Research 9 (3), 931-946, 2003 | 319 | 2003 |
| Targeted inhibitors of P-glycoprotein increase chemotherapeutic-induced mortality of multidrug resistant tumor cells AK Nanayakkara, CA Follit, G Chen, NS Williams, PD Vogel, JG Wise Scientific reports 8 (1), 1-18, 2018 | 278 | 2018 |
| Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration Y Zhang, A Desai, SY Yang, KB Bae, MI Antczak, SP Fink, S Tiwari, ... Science 348 (6240), aaa2340, 2015 | 277 | 2015 |
| Identification of NF-κ B-regulated genes induced by TNF α utilizing expression profiling and RNA interference A Zhou, S Scoggin, RB Gaynor, NS Williams Oncogene 22 (13), 2054-2064, 2003 | 247 | 2003 |
| Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma Y Shi, SK Lim, Q Liang, SV Iyer, HY Wang, Z Wang, X Xie, D Sun, ... Nature 567 (7748), 341-346, 2019 | 232 | 2019 |
| Regulation of VEGF-induced endothelial cell migration by mitochondrial reactive oxygen species Y Wang, QS Zang, Z Liu, Q Wu, D Maass, G Dulan, PW Shaul, L Melito, ... American Journal of Physiology-Cell Physiology 301 (3), C695-C704, 2011 | 219 | 2011 |
| Development of proneurogenic, neuroprotective small molecules KS MacMillan, J Naidoo, J Liang, L Melito, NS Williams, L Morlock, ... Journal of the American Chemical Society 133 (5), 1428-1437, 2011 | 209 | 2011 |
| A validated tumorgraft model reveals activity of dovitinib against renal cell carcinoma S Sivanand, S Peña-Llopis, H Zhao, B Kucejova, P Spence, ... Science translational medicine 4 (137), 137ra75-137ra75, 2012 | 199 | 2012 |
| Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer HS Kim, S Mendiratta, J Kim, CV Pecot, JE Larsen, I Zubovych, BY Seo, ... Cell 155 (3), 552-566, 2013 | 193 | 2013 |
| Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis R Tesla, HP Wolf, P Xu, J Drawbridge, SJ Estill, P Huntington, ... Proceedings of the National Academy of Sciences 109 (42), 17016-17021, 2012 | 178 | 2012 |
| Generation of Lytic Natural Killer 1.1+, Ly-49− Cells from Multipotential Murine Bone Marrow Progenitors in a Stroma-free Culture: Definition of Cytokine … NS Williams, TA Moore, JD Schatzle, IJ Puzanov, PV Sivakumar, A Zlotnik, ... The Journal of experimental medicine 186 (9), 1609-1614, 1997 | 174 | 1997 |
| Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease H De Jesús-Cortés, P Xu, J Drawbridge, SJ Estill, P Huntington, S Tran, ... Proceedings of the National Academy of Sciences 109 (42), 17010-17015, 2012 | 172 | 2012 |
| The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis AK Walker, PD Rivera, Q Wang, JC Chuang, S Tran, ... Molecular psychiatry 20 (4), 500-508, 2015 | 169 | 2015 |
| Identification of a population of CD4+ CTL that utilizes a perforin-rather than a Fas ligand-dependent cytotoxic mechanism. NS Williams, VH Engelhard The Journal of Immunology 156 (1), 153-159, 1996 | 168 | 1996 |
| Structure–activity relationship studies of small-molecule inhibitors of Wnt response J Lu, Z Ma, JC Hsieh, CW Fan, B Chen, JC Longgood, NS Williams, ... Bioorganic & medicinal chemistry letters 19 (14), 3825-3827, 2009 | 158 | 2009 |
