Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance L Hecker, NJ Logsdon, D Kurundkar, A Kurundkar, K Bernard, T Hock, ... Science translational medicine 6 (231), 231ra47-231ra47, 2014 | 685 | 2014 |
Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis Y Zhou, X Huang, L Hecker, D Kurundkar, A Kurundkar, H Liu, TH Jin, ... The Journal of clinical investigation 123 (3), 1096-1108, 2013 | 478 | 2013 |
Novel mechanisms for the antifibrotic action of nintedanib S Rangarajan, A Kurundkar, D Kurundkar, K Bernard, YY Sanders, ... American journal of respiratory cell and molecular biology 54 (1), 51-59, 2016 | 226 | 2016 |
SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury D Kurundkar, AR Kurundkar, NB Bone, EJ Becker Jr, W Liu, B Chacko, ... JCI insight 4 (1), 2019 | 125 | 2019 |
The matricellular protein CCN1 enhances TGF-β1/SMAD3-dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to lung injury AR Kurundkar, D Kurundkar, S Rangarajan, ML Locy, Y Zhou, RM Liu, ... The FASEB Journal 30 (6), 2135, 2016 | 80 | 2016 |
Impaired myofibroblast dedifferentiation contributes to nonresolving fibrosis in aging K Kato, NJ Logsdon, YJ Shin, S Palumbo, A Knox, JD Irish, ... American journal of respiratory cell and molecular biology 62 (5), 633-644, 2020 | 77 | 2020 |
Metformin, an Antidiabetic Agent Reduces Growth of Cutaneous Squamous Cell Carcinoma by Targeting mTOR Signaling Pathway† SC Chaudhary, D Kurundkar, CA Elmets, L Kopelovich, M Athar Photochemistry and photobiology 88 (5), 1149-1156, 2012 | 76 | 2012 |
Role of fibroblast growth factor 23 and klotho cross talk in idiopathic pulmonary fibrosis JW Barnes, D Duncan, S Helton, S Hutcheson, D Kurundkar, NJ Logsdon, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 317 (1 …, 2019 | 57 | 2019 |
Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model D Kurundkar, RK Srivastava, SC Chaudhary, ME Ballestas, L Kopelovich, ... Toxicology and applied pharmacology 266 (2), 233-244, 2013 | 49 | 2013 |
Restoration of SIRT3 gene expression by airway delivery resolves age-associated persistent lung fibrosis in mice M Rehan, D Kurundkar, AR Kurundkar, NJ Logsdon, SR Smith, D Chanda, ... Nature aging 1 (2), 205-217, 2021 | 39 | 2021 |
Mitochondrial uncoupling protein‐2 reprograms metabolism to induce oxidative stress and myofibroblast senescence in age‐associated lung fibrosis S Rangarajan, ML Locy, D Chanda, A Kurundkar, D Kurundkar, ... Aging Cell 21 (9), e13674, 2022 | 28 | 2022 |
Mesenchymal stromal cell aging impairs the self-organizing capacity of lung alveolar epithelial stem cells D Chanda, M Rehan, SR Smith, KG Dsouza, Y Wang, K Bernard, ... Elife 10, e68049, 2021 | 28 | 2021 |
Urokinase plasminogen activator overexpression reverses established lung fibrosis JC Horowitz, DJ Tschumperlin, KK Kim, JJ Osterholzer, N Subbotina, ... Thrombosis and haemostasis 119 (12), 1968-1980, 2019 | 22 | 2019 |
SIRT3 regulates senescence and secretory phenotype of lung fibroblasts D Kurundkar, A Kurundkar, VJ Thannickal B57. FIBROSIS BIOLOGY, A4019-A4019, 2016 | 3 | 2016 |
SIRT3 is decreased in senescent fibroblasts and negatively regulates myofibroblast differentiation D Kurundkar, A Kurundkar, S Rangarajan, VJ Thannickal C108. AGING: THE COMMON DENOMINATOR, A5311-A5311, 2015 | 1 | 2015 |
Clusterin deficiency promotes persistent fibrosis by impairing phagocytic clearance of collagen and promoting myofibroblast survival K Bernard, D Kurundkar, Y Wang, JS Deshane, VJ Thannickal D97. WELCOME BACK: ALVEOLAR MACROPHAGES IN PULMONARY FIBROSIS, A6095-A6095, 2015 | 1 | 2015 |
SIRT3 Promotes Resolution of Persistent Lung Fibrosis Associated with Aging M Rehan, D Kurundkar, A Kurundkar, NJ Logsdon, D Chanda, K Bernard, ... B20. THERAPEUTICS" 2020" IN LUNG DISEASE, A2785-A2785, 2020 | | 2020 |
Preclinical evaluation of a [89Zr]-labeled elastin-specific tracer for imaging of pulmonary fibrosis J Burkemper, T Aweda, S Fernandez, D Kurundkar, T Kulkarni, S Lapi Nuclear Medicine and Biology 72, S19, 2019 | | 2019 |
Mechanisms of the Anti-Fibrotic Effects of Pirfenidone KG Dsouza, NJ Logsdon, D Chanda, D Kurundkar, VJ Thannickal C62. FIBROBLAST BIOLOGY, A5334-A5334, 2019 | | 2019 |
Synthesis and Preliminary Evaluation of a [89Zr]-Labeled Elastin-Specific PET Tracer for Targeting Pulmonary Fibrosis J Burkemper, T Aweda, D Kurundkar, T Kulkarni, S Lapi Journal of Nuclear Medicine 59 (supplement 1), 265-265, 2018 | | 2018 |