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Solomon Nwaka
Solomon Nwaka
WHO, ANDI/UNOPS, Uni Freiburg, KU Leuven, Harvard Kennedy School, UNIDO/ICGEB, GO Uni
Dirección de correo verificada de andi-africa.org
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Antimalarial drug discovery: efficacy models for compound screening
DA Fidock, PJ Rosenthal, SL Croft, R Brun, S Nwaka
Nature Reviews Drug discovery 3 (6), 509-520, 2004
12182004
Innovative lead discovery strategies for tropical diseases
S Nwaka, A Hudson
Nature Reviews Drug Discovery 5 (11), 941-955, 2006
6582006
Genomic-scale prioritization of drug targets: the TDR Targets database
F Agüero, B Al-Lazikani, M Aslett, M Berriman, FS Buckner, RK Campbell, ...
Nature reviews Drug discovery 7 (11), 900-907, 2008
3592008
Virtual drug discovery and development for neglected diseases through public–private partnerships
S Nwaka, RG Ridley
Nature Reviews Drug Discovery 2 (11), 919-928, 2003
3552003
Molecular biology of trehalose and the trehalases in the yeast Saccharomyces cerevisiae
S Nwaka, H Holzer
Progress in nucleic acid research and molecular biology (K. Moldave Ed.) 58 …, 1997
2421997
Advancing drug innovation for neglected diseases—criteria for lead progression
S Nwaka, B Ramirez, R Brun, L Maes, F Douglas, R Ridley
PLoS neglected tropical diseases 3 (8), e440, 2009
1992009
Identification of Attractive Drug Targets in Neglected-Disease Pathogens Using an In Silico Approach
GJ Crowther, D Shanmugam, SJ Carmona, MA Doyle, C Hertz-Fowler, ...
PLoS neglected tropical diseases 4 (8), e804, 2010
1922010
Schistosomes: challenges in compound screening
B Ramirez, Q Bickle, F Yousif, F Fakorede, MA Mouries, S Nwaka
Expert opinion on drug discovery 2 (sup1), S53-S61, 2007
1672007
Activity of human Δ5 and Δ6 desaturases on multiple n-3 and n-6 polyunsaturated fatty acids
RJ de Antueno, LC Knickle, H Smith, ML Elliot, SJ Allen, S Nwaka, ...
FEBS letters 509 (1), 77-80, 2001
1552001
Induction of neutral trehalase Nth1 by heat and osmotic stress is controlled by STRE elements and Msn2/Msn4 transcription factors: variations of PKA effect during stress and growth
H Zähringer, JM Thevelein, S Nwaka
Molecular microbiology 35 (2), 397-406, 2000
1522000
Expression and Function of the Trehalase Genes NTH1 and YBR0106 in Saccharomyces cerevisiae (∗)
S Nwaka, M Kopp, H Holzer
Journal of Biological Chemistry 270 (17), 10193-10198, 1995
1421995
Deletion of the ATH1 gene in Saccharomyces cerevisiae prevents growth on trehalose
S Nwaka, B Mechler, H Holzer
FEBS letters 386 (2-3), 235-238, 1996
1341996
Phenotypic features of trehalase mutants in Saccharomyces cerevisiae
S Nwaka, B Mechler, M Destruelle, H Holzer
Febs Letters 360 (3), 286-290, 1995
1311995
Neutral trehalase Nth1p of Saccharomyces cerevisiae encoded by the NTH1 gene is a multiple stress responsive protein
H Zähringer, M Burgert, H Holzer, S Nwaka
FEBS letters 412 (3), 615-620, 1997
1131997
Opposite roles of trehalase activity in heat-shock recovery and heat-shock survival in Saccharomyces cerevisiae
S Wera, EDE SCHRIJVER, I Geyskens, S NWAKA, JM THEVELEIN
Biochemical journal 343 (3), 621-626, 1999
971999
Developing ANDI: a novel approach to health product R&D in Africa
S Nwaka, TB Ilunga, JS Da Silva, E Rial Verde, D Hackley, R De Vré, ...
PLoS Medicine 7 (6), e1000293, 2010
842010
Is thermotolerance of yeast dependent on trehalose accumulation?
S Nwaka, M Kopp, M Burgert, I Deuchler, I Kienle, H Holzer
FEBS letters 344 (2-3), 225-228, 1994
761994
Analysis of pan-African Centres of excellence in health innovation highlights opportunities and challenges for local innovation and financing in the continent
S Nwaka, A Ochem, D Besson, B Ramirez, F Fakorede, S Botros, ...
BMC international health and human rights 12, 1-15, 2012
672012
Mission possible
AL Hopkins, MJ Witty, S Nwaka
Nature 449 (7159), 166-169, 2007
662007
Drug discovery and beyond: the role of public-private partnerships in improving access to new malaria medicines
S Nwaka
Transactions of the Royal Society of Tropical Medicine and Hygiene 99 …, 2005
652005
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Artículos 1–20