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Paul J. Wrighton
Paul J. Wrighton
Brigham and Women's Hospital
Dirección de correo verificada de partners.org
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A defined glycosaminoglycan-binding substratum for human pluripotent stem cells
JR Klim, L Li, PJ Wrighton, MS Piekarczyk, LL Kiessling
Nature methods 7 (12), 989-994, 2010
3272010
Substratum-induced differentiation of human pluripotent stem cells reveals the coactivator YAP is a potent regulator of neuronal specification
S Musah, PJ Wrighton, Y Zaltsman, X Zhong, S Zorn, MB Parlato, C Hsiao, ...
Proceedings of the National Academy of Sciences 111 (38), 13805-13810, 2014
1882014
Glycosaminoglycan-binding hydrogels enable mechanical control of human pluripotent stem cell self-renewal
S Musah, SA Morin, PJ Wrighton, DB Zwick, S Jin, LL Kiessling
ACS nano 6 (11), 10168-10177, 2012
1712012
YAP regulates hematopoietic stem cell formation in response to the biomechanical forces of blood flow
V Lundin, WW Sugden, LN Theodore, PM Sousa, A Han, S Chou, ...
Developmental cell 52 (4), 446-460. e5, 2020
762020
Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins
PJ Wrighton, JR Klim, BA Hernandez, CH Koonce, TJ Kamp, LL Kiessling
Proceedings of the National Academy of Sciences 111 (51), 18126-18131, 2014
662014
Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood
O Weeks, GD Bossé, IM Oderberg, S Akle, Y Houvras, PJ Wrighton, ...
The Journal of clinical investigation 130 (5), 2252-2269, 2020
432020
There is something fishy about liver cancer: zebrafish models of hepatocellular carcinoma
PJ Wrighton, IM Oderberg, W Goessling
Cellular and molecular gastroenterology and hepatology 8 (3), 347-363, 2019
422019
Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy
PJ Wrighton, A Shwartz, JM Heo, ED Quenzer, KA LaBella, JW Harper, ...
Journal of cell science 134 (4), jcs256255, 2021
362021
Synthetic CRISPR/Cas9 reagents facilitate genome editing and homology directed repair
SE DiNapoli, R Martinez-McFaline, CK Gribbin, PJ Wrighton, CA Balgobin, ...
Nucleic acids research 48 (7), e38-e38, 2020
352020
Small-Molecule-Modified Surfaces Engage Cells through the αvβ3 Integrin
JR Klim, AJ Fowler, AH Courtney, PJ Wrighton, RTC Sheridan, ML Wong, ...
ACS Chemical Biology 7 (3), 518-525, 2012
212012
Forces of change: mechanics underlying formation of functional 3D organ buds
PJ Wrighton, LL Kiessling
Cell stem cell 16 (5), 453-454, 2015
112015
A quantitative single-cell assay for retrograde membrane traffic enables rapid detection of defects in cellular organization
P Luong, Q Li, PF Chen, PJ Wrighton, D Chang, S Dwyer, MT Bayer, ...
Molecular biology of the cell 31 (7), 511-519, 2020
82020
A total synthetic approach to CRISPR/Cas9 genome editing and homology directed repair
SE DiNapoli, R Martinez-McFaline, CK Gribbin, P Wrighton, CA Balgobin, ...
BioRxiv, 359984, 2018
42018
YAP regulates hematopoietic stem cell formation in response to the biophysical forces of blood flow
LN Theodore, V Lundin, PJ Wrighton, AG Cox, P Sousa, W Goessling, ...
Blood 130, 1147, 2017
22017
Bnip3lb Regulated Mitophagy Maintains the Embryonic Pool of Hematopoietic Stem Cells by Protecting Them from ROS Induced Apoptosis
E Meader, PJ Wrighton, I Oderberg, M Leder, M Walcheck, T Long, ...
Blood 140 (Supplement 1), 8570-8571, 2022
12022
Quantitative intravital imaging reveals in vivo dynamics of physiological-stress induced mitophagy
PJ Wrighton, A Shwartz, J Heo, ED Quenzer, KA LaBella, J Wade
12020
Live imaging defines the dynamics and molecular basis of in vivo mitophagy
PJ Wrighton, A Shwartz, JM Heo, ED Quenzer, KA LaBella, JW Harper, ...
bioRxiv, 2020.03. 26.010405, 2020
12020
Ezh1 inhibits commitment to hemogenic fate and HSPC formation during vertebrate development
R Soto, LT Vo, M Hachimi, JM Frame, PJ Wrighton, W Goessling, ...
Blood 134, 3710, 2019
12019
Investigating the role of EZH1 in developmental hematopoiesis
R Soto, P Wrighton, G Daley, W Goessling, T North
Experimental Hematology 76, S86, 2019
12019
3017–MECHANISMS OF FLOW-DRIVEN TRANSCRIPTIONAL CONTROL OF HEMATOPOIETIC STEM CELL DEVELOPMENT VIA YAP/TAZ REGULATION
W Sugden, P Wrighton, Z LeBlanc, MG di Tillio, M Najia, E Quenzer, ...
Experimental Hematology 111, S53, 2022
2022
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Artículos 1–20