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Laura A Mike
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Overcoming the heme paradox: heme toxicity and tolerance in bacterial pathogens
LL Anzaldi, EP Skaar
Infection and immunity 78 (12), 4977-4989, 2010
3462010
Siderophore vaccine conjugates protect against uropathogenic Escherichia coli urinary tract infection
LA Mike, SN Smith, CA Sumner, KA Eaton, HLT Mobley
Proceedings of the National Academy of Sciences 113 (47), 13468-13473, 2016
942016
Menaquinone biosynthesis potentiates haem toxicity in Staphylococcus aureus
CA Wakeman, ND Hammer, DL Stauff, AS Attia, LL Anzaldi, SI Dikalov, ...
Molecular microbiology 86 (6), 1376-1392, 2012
932012
A systematic analysis of hypermucoviscosity and capsule reveals distinct and overlapping genes that impact Klebsiella pneumoniae fitness
LA Mike, AJ Stark, VS Forsyth, J Vornhagen, SN Smith, MA Bachman, ...
PLoS pathogens 17 (3), e1009376, 2021
722021
Nfu facilitates the maturation of iron‐sulfur proteins and participates in virulence in Staphylococcus aureus
AA Mashruwala, YY Pang, Z Rosario‐Cruz, HK Chahal, MA Benson, ...
Molecular microbiology 95 (3), 383-409, 2015
692015
Activation of heme biosynthesis by a small molecule that is toxic to fermenting Staphylococcus aureus
LA Mike, BF Dutter, DL Stauff, JL Moore, NP Vitko, O Aranmolate, ...
Proceedings of the National Academy of Sciences 110 (20), 8206-8211, 2013
572013
Bacillithiol has a role in Fe–S cluster biogenesis in Staphylococcus aureus
Z Rosario‐Cruz, HK Chahal, LA Mike, EP Skaar, JM Boyd
Molecular microbiology 98 (2), 218-242, 2015
532015
Two-Component System Cross-Regulation Integrates Bacillus anthracis Response to Heme and Cell Envelope Stress
LA Mike, JE Choby, PR Brinkman, LQ Olive, BF Dutter, SJ Ivan, CM Gibbs, ...
PLoS pathogens 10 (3), e1004044, 2014
522014
Optimization of an experimental vaccine to prevent Escherichia coli urinary tract infection
VS Forsyth, SD Himpsl, SN Smith, CA Sarkissian, LA Mike, JA Stocki, ...
MBio 11 (2), 10.1128/mbio. 00555-20, 2020
41*2020
A small-molecule inhibitor of iron-sulfur cluster assembly uncovers a link between virulence regulation and metabolism in Staphylococcus aureus
JE Choby, LA Mike, AA Mashruwala, BF Dutter, PM Dunman, ...
Cell chemical biology 23 (11), 1351-1361, 2016
342016
Directed evolution of a pyruvate aldolase to recognize a long chain acyl substrate
M Cheriyan, MJ Walters, BD Kang, LL Anzaldi, EJ Toone, CA Fierke
Bioorganic & medicinal chemistry 19 (21), 6447-6453, 2011
252011
Age‐dependent photoionization thresholds of melanosomes and lipofuscin isolated from human retinal pigment epithelium cells
L Hong, J Garguilo, L Anzaldi, GS Edwards, RJ Nemanich, JD Simon
Photochemistry and photobiology 82 (6), 1475-1481, 2006
222006
Dependence of Fluorescence Quenching of a Poly(p-phenyleneethynylene) Polyelectrolyte on the Electrostatic and Hydrophobic Properties of the Quencher
P Kaur, M Wu, L Anzaldi, DH Waldeck, C Xue, H Liu
Langmuir 23 (26), 13203-13208, 2007
152007
The evolution of a superbug: how Staphylococcus aureus overcomes its unique susceptibility to polyamines
LL Anzaldi, EP Skaar
Molecular microbiology 82 (1), 1-3, 2011
132011
Decoupling Activation of Heme Biosynthesis from Anaerobic Toxicity in a Molecule Active in Staphylococcus aureus
BF Dutter, LA Mike, PR Reid, KM Chong, SJ Ramos-Hunter, EP Skaar, ...
ACS chemical biology 11 (5), 1354-1361, 2016
112016
Urine-mediated suppression of Klebsiella pneumoniae mucoidy is counteracted by spontaneous Wzc variants altering capsule chain length
S Khadka, BE Ring, RS Walker, LR Krzeminski, DA Pariseau, ...
Msphere 8 (5), e00288-23, 2023
10*2023
Discovery of nicoyamycin A, an inhibitor of uropathogenic Escherichia coli growth in low iron environments
LA Mike, A Tripathi, CM Blankenship, A Saluk, PJ Schultz, ...
Chemical communications 53 (95), 12778-12781, 2017
82017
The Klebsiella pneumoniae ter Operon Enhances Stress Tolerance
S Mason, J Vornhagen, SN Smith, LA Mike, HLT Mobley, MA Bachman
Infection and Immunity 91 (2), e00559-22, 2023
52023
494 Skaar EP, Torres VJ, Nauseef WM, Boyd JM. 2015
AA Mashruwala, YY Pang, Z Rosario-Cruz, HK Chahal, MA Benson, ...
Nfu facilitates the maturation 495, 383-409, 0
3
Compositions and methods for treating microbial infections
EP Skaar, L Anzaldi, G Sulikowski, A Waterson, P Reid
US Patent App. 14/417,277, 2015
22015
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