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Clayton E Friedman
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Single-cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation
CE Friedman, Q Nguyen, SW Lukowski, A Helfer, HS Chiu, J Miklas, ...
Cell stem cell 23 (4), 586-598. e8, 2018
2282018
Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells
NJ Palpant, L Pabon, CE Friedman, M Roberts, B Hadland, ...
Nature protocols 12 (1), 15-31, 2017
1962017
A transcribed enhancer dictates mesendoderm specification in pluripotency
M Alexanian, D Maric, SP Jenkinson, M Mina, CE Friedman, CC Ting, ...
Nature communications 8 (1), 1806, 2017
632017
Vascular cells improve functionality of human cardiac organoids
HK Voges, SR Foster, L Reynolds, BL Parker, L Devilée, GA Quaife-Ryan, ...
Cell Reports 42 (5), 2023
212023
Cardiomyocyte Apoptosis Is Associated with Contractile Dysfunction in Stem Cell Model of MYH7 E848G Hypertrophic Cardiomyopathy
AM Loiben, WM Chien, CE Friedman, LSL Chao, G Weber, A Goldstein, ...
International Journal of Molecular Sciences 24 (5), 4909, 2023
42023
CRaTER enrichment for on-target gene editing enables generation of variant libraries in hiPSCs
CE Friedman, S Fayer, S Pendyala, WM Chien, A Loiben, L Tran, ...
Journal of Molecular and Cellular Cardiology 179, 60-71, 2023
32023
Generation of human iPSC line from an arrhythmogenic cardiomyopathy patient with a DSP protein-truncating variant
A Loiben, CE Friedman, WM Chien, A Stempien-Otero, S Lin, KC Yang
Stem cell research 66, 102987, 2023
22023
Multiplexed Functional Assessments of MYH7 Variants in Human Cardiomyocytes
CE Friedman, S Fayer, S Pendyala, WM Chien, A Loiben, L Tran, ...
Circulation: Genomic and Precision Medicine, e004377, 2024
12024
HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function
CE Friedman, SW Cheetham, S Negi, RJ Mills, M Ogawa, MA Redd, ...
Developmental Cell 59 (1), 91-107. e6, 2024
12024
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