MyD88-dependent expansion of an immature GR-1+CD11b+ population induces T cell suppression and Th2 polarization in sepsis MJ Delano, PO Scumpia, JS Weinstein, D Coco, S Nagaraj, ... The Journal of experimental medicine 204 (6), 1463-1474, 2007 | 811 | 2007 |
Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8 J Vollmer, S Tluk, C Schmitz, S Hamm, M Jurk, A Forsbach, S Akira, ... The Journal of experimental medicine 202 (11), 1575-1585, 2005 | 634 | 2005 |
Type I interferon suppresses type II interferon–triggered human anti-mycobacterial responses RMB Teles, TG Graeber, SR Krutzik, D Montoya, M Schenk, DJ Lee, ... Science 339 (6126), 1448-1453, 2013 | 461 | 2013 |
A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma AG Cuenca, MJ Delano, KM Kelly-Scumpia, C Moreno, PO Scumpia, ... Molecular medicine 17, 281-292, 2011 | 404 | 2011 |
Deficiency of the type I interferon receptor protects mice from experimental lupus DC Nacionales, KM Kelly‐Scumpia, PY Lee, JS Weinstein, R Lyons, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2007 | 232 | 2007 |
TLR7-dependent and FcγR-independent production of type I interferon in experimental mouse lupus PY Lee, Y Kumagai, Y Li, O Takeuchi, H Yoshida, J Weinstein, ES Kellner, ... The Journal of experimental medicine 205 (13), 2995-3006, 2008 | 227 | 2008 |
Sepsis induces early alterations in innate immunity that impact mortality to secondary infection MJ Delano, T Thayer, S Gabrilovich, KM Kelly-Scumpia, RD Winfield, ... The Journal of Immunology 186 (1), 195-202, 2011 | 198 | 2011 |
B cells enhance early innate immune responses during bacterial sepsis KM Kelly-Scumpia, PO Scumpia, JS Weinstein, MJ Delano, AG Cuenca, ... Journal of Experimental Medicine 208 (8), 1673-1682, 2011 | 195 | 2011 |
Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists JL Wynn, PO Scumpia, RD Winfield, MJ Delano, K Kelly-Scumpia, ... Blood, The Journal of the American Society of Hematology 112 (5), 1750-1758, 2008 | 186 | 2008 |
Increased natural CD4+ CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis PO Scumpia, MJ Delano, KM Kelly, KA O’Malley, PA Efron, PF McAuliffe, ... The Journal of Immunology 177 (11), 7943-7949, 2006 | 169 | 2006 |
Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling MJ Delano, KM Kelly-Scumpia, TC Thayer, RD Winfield, PO Scumpia, ... The Journal of Immunology 187 (2), 911-918, 2011 | 166 | 2011 |
Cutting edge: bacterial infection induces hematopoietic stem and progenitor cell expansion in the absence of TLR signaling PO Scumpia, KM Kelly-Scumpia, MJ Delano, JS Weinstein, AG Cuenca, ... The Journal of Immunology 184 (5), 2247-2251, 2010 | 161 | 2010 |
Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10 KM Kelly-Scumpia, PO Scumpia, MJ Delano, JS Weinstein, AG Cuenca, ... Journal of Experimental Medicine 207 (2), 319-326, 2010 | 151 | 2010 |
A macrophage response to Mycobacterium leprae phenolic glycolipid initiates nerve damage in leprosy CA Madigan, CJ Cambier, KM Kelly-Scumpia, PO Scumpia, TY Cheng, ... Cell 170 (5), 973-985. e10, 2017 | 127 | 2017 |
Type I interferon production by tertiary lymphoid tissue developing in response to 2, 6, 10, 14-tetramethyl-pentadecane (pristane) DC Nacionales, KM Kelly, PY Lee, H Zhuang, Y Li, JS Weinstein, E Sobel, ... The American journal of pathology 168 (4), 1227-1240, 2006 | 127 | 2006 |
Double‐stranded RNA signals antiviral and inflammatory programs and dysfunctional glutamate transport in TLR3‐expressing astrocytes PO Scumpia, KM Kelly, WH Reeves, BR Stevens Glia 52 (2), 153-162, 2005 | 109 | 2005 |
“Endogenous adjuvant” activity of the RNA components of lupus autoantigens Sm/RNP and Ro 60 KM Kelly, H Zhuang, DC Nacionales, PO Scumpia, R Lyons, J Akaogi, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2006 | 102 | 2006 |
Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis PO Scumpia, MJ Delano, KM Kelly-Scumpia, JS Weinstein, JL Wynn, ... Blood, The Journal of the American Society of Hematology 110 (10), 3673-3681, 2007 | 92 | 2007 |
Cecal ligation and puncture AG Cuenca, MJ Delano, KM Kelly‐Scumpia, LL Moldawer, PA Efron Current protocols in immunology 91 (1), 19.13. 1-19.13. 11, 2010 | 90 | 2010 |
Association of anti-nucleoprotein autoantibodies with upregulation of Type I interferon-inducible gene transcripts and dendritic cell maturation in systemic lupus erythematosus H Zhuang, S Narain, E Sobel, PY Lee, DC Nacionales, KM Kelly, ... Clinical immunology 117 (3), 238-250, 2005 | 83 | 2005 |