Protein disulfide isomerase: the structure of oxidative folding CW Gruber, M Čemažar, B Heras, JL Martin, DJ Craik Trends in biochemical sciences 31 (8), 455-464, 2006 | 403 | 2006 |
DSB proteins and bacterial pathogenicity B Heras, SR Shouldice, M Totsika, MJ Scanlon, MA Schembri, JL Martin Nature Reviews Microbiology 7 (3), 215-225, 2009 | 337 | 2009 |
Post-crystallization treatments for improving diffraction quality of protein crystals B Heras, JL Martin Acta Crystallographica Section D: Biological Crystallography 61 (9), 1173-1180, 2005 | 302 | 2005 |
Targeting virulence not viability in the search for future antibacterials B Heras, MJ Scanlon, JL Martin British journal of clinical pharmacology 79 (2), 208-215, 2015 | 191 | 2015 |
The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping B Heras, M Totsika, KM Peters, JJ Paxman, CL Gee, RJ Jarrott, ... Proceedings of the National Academy of Sciences 111 (1), 457-462, 2014 | 147 | 2014 |
Crystal structures of the DsbG disulfide isomerase reveal an unstable disulfide B Heras, MA Edeling, HJ Schirra, S Raina, JL Martin Proceedings of the National Academy of Sciences 101 (24), 8876-8881, 2004 | 136 | 2004 |
Properties of the thioredoxin fold superfamily are modulated by a single amino acid residue G Ren, D Stephan, Z Xu, Y Zheng, D Tang, RS Harrison, M Kurz, R Jarrott, ... Journal of biological chemistry 284 (15), 10150-10159, 2009 | 135 | 2009 |
Structure and function of DsbA, a key bacterial oxidative folding catalyst SR Shouldice, B Heras, PM Walden, M Totsika, MA Schembri, JL Martin Antioxidants & redox signaling 14 (9), 1729-1760, 2011 | 129 | 2011 |
Dehydration converts DsbG crystal diffraction from low to high resolution B Heras, MA Edeling, KA Byriel, A Jones, S Raina, JL Martin Structure 11 (2), 139-145, 2003 | 114 | 2003 |
Characterization of Two Homologous Disulfide Bond Systems Involved in Virulence Factor Biogenesis in Uropathogenic Escherichia coli CFT073 M Totsika, B Heras, DJ Wurpel, MA Schembri Journal of bacteriology 191 (12), 3901-3908, 2009 | 90 | 2009 |
New 1-aryl-3-(4-arylpiperazin-1-yl) propane derivatives, with dual action at 5-HT1A serotonin receptors and serotonin transporter, as a new class of antidepressants J Martínez-Esparza, AM Oficialdegui, S Pérez-Silanes, B Heras, L Orús, ... Journal of medicinal chemistry 44 (3), 418-428, 2001 | 85 | 2001 |
A molecular chameleon for mapping subcellular polarity in an unfolded proteome environment TC Owyong, P Subedi, J Deng, E Hinde, JJ Paxman, JM White, W Chen, ... Angewandte Chemie 132 (25), 10215-10221, 2020 | 82 | 2020 |
Staphylococcus aureus DsbA does not have a destabilizing disulfide: a new paradigm for bacterial oxidative folding B Heras, M Kurz, R Jarrott, SR Shouldice, P Frei, G Robin, M Cemazar, ... Journal of biological chemistry 283 (7), 4261-4271, 2008 | 81 | 2008 |
The name's bond…… disulfide bond B Heras, M Kurz, SR Shouldice, JL Martin Current opinion in structural biology 17 (6), 691-698, 2007 | 70 | 2007 |
Targeting bacterial Dsb proteins for the development of anti-virulence agents RP Smith, JJ Paxman, MJ Scanlon, B Heras Molecules 21 (7), 811, 2016 | 69 | 2016 |
Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium B Heras, M Totsika, R Jarrott, SR Shouldice, G Gunčar, MES Achard, ... Journal of biological chemistry 285 (24), 18423-18432, 2010 | 63 | 2010 |
Application of Fragment‐Based Screening to the Design of Inhibitors of Escherichia coli DsbA LA Adams, P Sharma, B Mohanty, OV Ilyichova, MD Mulcair, ML Williams, ... Angewandte Chemie 127 (7), 2207-2212, 2015 | 57 | 2015 |
New 3-[4-(aryl) piperazin-1-yl]-1-(benzo [b] thiophen-3-yl) propane derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of … J Martínez, S Pérez, AM Oficialdegui, B Heras, L Orús, H Villanueva, ... European journal of medicinal chemistry 36 (1), 55-61, 2001 | 56 | 2001 |
In vivo oxidative protein folding can be facilitated by oxidation–reduction cycling SR Shouldice, SH Cho, D Boyd, B Heras, M Eser, J Beckwith, P Riggs, ... Molecular microbiology 75 (1), 13-28, 2010 | 53 | 2010 |
Structure and function of the oxidoreductase DsbA1 from Neisseria meningitidis JP Vivian, J Scoullar, K Rimmer, SR Bushell, T Beddoe, MCJ Wilce, ... Journal of molecular biology 394 (5), 931-943, 2009 | 47 | 2009 |