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Jason R. Dobson
Jason R. Dobson
Bristol-Meyers Squibb
Dirección de correo verificada de bms.com
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Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin
KA Hoadley, C Yau, DM Wolf, AD Cherniack, D Tamborero, S Ng, ...
Cell 158 (4), 929-944, 2014
15232014
Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes
MDM Leiserson, F Vandin, HT Wu, JR Dobson, JV Eldridge, JL Thomas, ...
Nature genetics 47 (2), 106-114, 2015
9152015
Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases
YNP Chen, MJ LaMarche, HM Chan, P Fekkes, J Garcia-Fortanet, ...
Nature 535 (7610), 148-152, 2016
7712016
A phase I study of the cyclin-dependent kinase 4/6 inhibitor ribociclib (LEE011) in patients with advanced solid tumors and lymphomas
JR Infante, PA Cassier, JF Gerecitano, PO Witteveen, R Chugh, V Ribrag, ...
Clinical Cancer Research 22 (23), 5696-5705, 2016
3022016
Identifying driver mutations in sequenced cancer genomes: computational approaches to enable precision medicine
BJ Raphael, JR Dobson, L Oesper, F Vandin
Genome medicine 6, 1-17, 2014
2492014
Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells
J Pratap, JJ Wixted, T Gaur, SK Zaidi, J Dobson, KD Gokul, S Hussain, ...
Cancer research 68 (19), 7795-7802, 2008
2232008
A phase I study of the CDK4/6 inhibitor ribociclib (LEE011) in pediatric patients with malignant rhabdoid tumors, neuroblastoma, and other solid tumors
B Geoerger, F Bourdeaut, SG DuBois, M Fischer, JI Geller, NG Gottardo, ...
Clinical Cancer Research 23 (10), 2433-2441, 2017
1602017
Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis
H Wu, TW Whitfield, JAR Gordon, JR Dobson, PWL Tai, AJ van Wijnen, ...
Genome biology 15, 1-17, 2014
1452014
Genomic analysis of nasopharyngeal carcinoma reveals TME-based subtypes
L Zhang, KD MacIsaac, T Zhou, PY Huang, C Xin, JR Dobson, K Yu, ...
Molecular Cancer Research 15 (12), 1722-1732, 2017
1292017
Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility
DT Leong, J Lim, X Goh, J Pratap, BP Pereira, HS Kwok, SS Nathan, ...
Breast Cancer Research 12, 1-12, 2010
772010
Phase 1 study of single-agent WNT974, a first-in-class Porcupine inhibitor, in patients with advanced solid tumours
J Rodon, G Argilés, RM Connolly, U Vaishampayan, M de Jonge, ...
British journal of cancer 125 (1), 28-37, 2021
762021
The SWI/SNF ATPases are required for triple negative breast cancer cell proliferation
Q Wu, P Madany, J Akech, JR Dobson, S Douthwright, G Browne, ...
Journal of cellular physiology 230 (11), 2683-2694, 2015
722015
Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition
D Hong, TL Messier, CE Tye, JR Dobson, AJ Fritz, KR Sikora, G Browne, ...
Oncotarget 8 (11), 17610, 2017
622017
The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation
Q Wu, P Madany, JR Dobson, JM Schnabl, S Sharma, TC Smith, ...
Oncotarget 7 (25), 38270, 2016
622016
hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3
JR Dobson, H Taipaleenmäki, YJ Hu, D Hong, AJ Van Wijnen, JL Stein, ...
Cancer cell international 14, 1-14, 2014
582014
Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes
SA Ali, SK Zaidi, JR Dobson, AR Shakoori, JB Lian, JL Stein, ...
Proceedings of the National Academy of Sciences 107 (9), 4165-4169, 2010
562010
A RUNX2–HDAC1 co-repressor complex regulates rRNA gene expression by modulating UBF acetylation
SA Ali, JR Dobson, JB Lian, JL Stein, AJ Van Wijnen, SK Zaidi, GS Stein
Journal of cell science 125 (11), 2732-2739, 2012
542012
Expansion of GA Dinucleotide Repeats Increases the Density of CLAMP Binding Sites on the X-Chromosome to Promote Drosophila Dosage Compensation
G Kuzu, EG Kaye, J Chery, T Siggers, L Yang, JR Dobson, S Boor, J Bliss, ...
PLoS genetics 12 (7), e1006120, 2016
472016
The bone-specific Runx2-P1 promoter displays conserved three-dimensional chromatin structure with the syntenic Supt3h promoter
AR Barutcu, PWL Tai, H Wu, JAR Gordon, TW Whitfield, JR Dobson, ...
Nucleic acids research 42 (16), 10360-10372, 2014
302014
Expression of the IL‐11 Gene in Metastatic Cells Is Supported by Runx2‐Smad and Runx2‐cJun Complexes Induced by TGFβ1
X Zhang, H Wu, JR Dobson, G Browne, D Hong, J Akech, LR Languino, ...
Journal of cellular biochemistry 116 (9), 2098-2108, 2015
272015
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Artículos 1–20