| Coumarins: old compounds with novel promising therapeutic perspectives ME Riveiro, N De Kimpe, A Moglioni, R Vazquez, F Monczor, C Shayo, ... Current medicinal chemistry 17 (13), 1325-1338, 2010 | 507 | 2010 |
| Mepyramine, a histamine H1 receptor inverse agonist, binds preferentially to a G protein-coupled form of the receptor and sequesters G protein CP Fitzsimons, F Monczor, N Fernández, C Shayo, C Davio Journal of Biological Chemistry 279 (33), 34431-34439, 2004 | 92 | 2004 |
| Current knowledge and perspectives on histamine H1 and H2 receptor pharmacology: functional selectivity, receptor crosstalk, and repositioning of classic histaminergic ligands F Monczor, N Fernandez Molecular pharmacology 90 (5), 640-648, 2016 | 71 | 2016 |
| Tiotidine, a Histamine H2 Receptor Inverse Agonist That Binds with High Affinity to an Inactive G-Protein—Coupled Form of the Receptor. Experimental Support for the Cubic … F Monczor, N Fernandez, BL Legnazzi, ME Riveiro, A Baldi, C Shayo, ... Molecular pharmacology 64 (2), 512-520, 2003 | 58 | 2003 |
| Histamine H2 receptor desensitization: involvement of a select array of G protein-coupled receptor kinases C Shayo, N Fernandez, BL Legnazzi, F Monczor, A Mladovan, A Baldi, ... Molecular Pharmacology 60 (5), 1049-1056, 2001 | 58 | 2001 |
| Induction of cell differentiation in human leukemia U-937 cells by 5-oxygenated-6, 7-methylenedioxycoumarins from Pterocaulon polystachyum ME Riveiro, C Shayo, F Monczor, N Fernández, A Baldi, N De Kimpe, ... Cancer letters 210 (2), 179-188, 2004 | 55 | 2004 |
| Effects of the pesticide chlorpyrifos on breast cancer disease. Implication of epigenetic mechanisms C Ventura, CD Zappia, M Lasagna, W Pavicic, S Richard, AD Bolzan, ... The Journal of steroid biochemistry and molecular biology 186, 96-104, 2019 | 46 | 2019 |
| Cross-desensitization and cointernalization of H1 and H2 histamine receptors reveal new insights into histamine signal integration N Alonso, N Fernandez, C Notcovich, F Monczor, M Simaan, A Baldi, ... Molecular pharmacology 83 (5), 1087-1098, 2013 | 42 | 2013 |
| Roles of phosphorylation-dependent and-independent mechanisms in the regulation of histamine H2 receptor by G protein-coupled receptor kinase 2 N Fernandez, FL Gottardo, MN Alonso, F Monczor, C Shayo, C Davio Journal of Biological Chemistry 286 (33), 28697-28706, 2011 | 42 | 2011 |
| Expression of a G protein-coupled receptor (GPCR) leads to attenuation of signaling by other GPCRs: experimental evidence for a spontaneous GPCR constitutive inactive form MR Tubio, N Fernandez, CP Fitzsimons, S Copsel, S Santiago, C Shayo, ... Journal of biological chemistry 285 (20), 14990-14998, 2010 | 40 | 2010 |
| Physiological implications of biased signaling at histamine H2 receptors N Alonso, CD Zappia, M Cabrera, CA Davio, C Shayo, F Monczor, ... Frontiers in pharmacology 6, 131888, 2015 | 38 | 2015 |
| Rapid desensitization and slow recovery of the cyclic AMP response mediated by histamine H2 receptors in the U937 cell line BL Legnazzi, C Shayo, F Monczor, ME Martin, N Fernandez, A Brodsky, ... Biochemical pharmacology 60 (2), 159-166, 2000 | 34 | 2000 |
| Histamine H2 receptor trafficking: role of arrestin, dynamin, and clathrin in histamine H2 receptor internalization N Fernandez, F Monczor, A Baldi, C Davio, C Shayo Molecular Pharmacology 74 (4), 1109-1118, 2008 | 33 | 2008 |
| Reduction of G protein-coupled receptor kinase 2 expression in U-937 cells attenuates H2 histamine receptor desensitization and induces cell maturation N Fernández, F Monczor, B Lemos, C Notcovich, A Baldi, C Davio, ... Molecular pharmacology 62 (6), 1506-1514, 2002 | 33 | 2002 |
| Antihistaminergics and inverse agonism: potential therapeutic applications F Monczor, N Fernandez, CP Fitzsimons, C Shayo, C Davio European journal of pharmacology 715 (1-3), 26-32, 2013 | 32 | 2013 |
| The time-course of cyclic AMP signaling is critical for leukemia U-937 cell differentiation C Shayo, BL Legnazzi, F Monczor, N Fernández, ME Riveiro, A Baldi, ... Biochemical and biophysical research communications 314 (3), 798-804, 2004 | 31 | 2004 |
| Signal transduction mechanism of biased ligands at histamine H2 receptors N Alonso, F Monczor, E Echeverría, C Davio, C Shayo, N Fernández Biochemical Journal 459 (1), 117-126, 2014 | 26 | 2014 |
| Identification of MRP4/ABCC4 as a target for reducing the proliferation of pancreatic ductal adenocarcinoma cells by modulating the cAMP efflux A Carozzo, A Yaneff, N Gomez, N Di Siervi, A Sahores, F Diez, AI Attorresi, ... Molecular pharmacology 96 (1), 13-25, 2019 | 24 | 2019 |
| Histamine H2 receptor overexpression induces U937 cell differentiation despite triggered mechanisms to attenuate cAMP signalling F Monczor, N Fernandez, E Riveiro, A Mladovan, A Baldi, C Shayo, ... Biochemical pharmacology 71 (8), 1219-1228, 2006 | 22 | 2006 |
| Effects of histamine H1 receptor signaling on glucocorticoid receptor activity. Role of canonical and non-canonical pathways CD Zappia, G Granja-Galeano, N Fernández, C Shayo, C Davio, ... Scientific reports 5 (1), 17476, 2015 | 21 | 2015 |
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