Efficient chiral monophosphorus ligands for asymmetric Suzuki–Miyaura coupling reactions W Tang, ND Patel, G Xu, X Xu, J Savoie, S Ma, MH Hao, S Keshipeddy, ... Organic letters 14 (9), 2258-2261, 2012 | 167 | 2012 |
A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells KS Wun, G Cameron, O Patel, SS Pang, DG Pellicci, LC Sullivan, ... Immunity 34 (3), 327-339, 2011 | 132 | 2011 |
Efficient monophosphorus ligands for palladium-catalyzed Miyaura borylation W Tang, S Keshipeddy, Y Zhang, X Wei, J Savoie, ND Patel, NK Yee, ... Organic Letters 13 (6), 1366-1369, 2011 | 128 | 2011 |
Adaptability of the semi‐invariant natural killer T‐cell receptor towards structurally diverse CD1d‐restricted ligands WC Florence, C Xia, LE Gordy, W Chen, Y Zhang, J Scott‐Browne, ... The EMBO journal 28 (22), 3579-3590, 2009 | 55 | 2009 |
Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata N G-Dayanandan, JL Paulsen, K Viswanathan, S Keshipeddy, ... Journal of Medicinal Chemistry 57 (6), 2643-2656, 2014 | 44 | 2014 |
Atypical natural killer T-cell receptor recognition of CD1d–lipid antigens J Le Nours, T Praveena, DG Pellicci, NA Gherardin, FJ Ross, RT Lim, ... Nature communications 7 (1), 10570, 2016 | 40 | 2016 |
Human and mouse type I natural killer T cell antigen receptors exhibit different fine specificities for CD1d-antigen complex KS Wun, F Ross, O Patel, GS Besra, SA Porcelli, SK Richardson, ... Journal of Biological Chemistry 287 (46), 39139-39148, 2012 | 40 | 2012 |
Nonracemic Antifolates Stereoselectively Recruit Alternate Cofactors and Overcome Resistance in S. aureus S Keshipeddy, SM Reeve, AC Anderson, DL Wright Journal of the American Chemical Society 137 (28), 8983-8990, 2015 | 39 | 2015 |
Toward a formal synthesis of laureatin: unexpected rearrangements involving cyclic ether nucleophiles S Keshipeddy, I Martı́nez, BF Castillo, MD Morton, AR Howell The Journal of Organic Chemistry 77 (18), 7883-7890, 2012 | 37 | 2012 |
Charged nonclassical antifolates with activity against gram-positive and gram-negative pathogens E Scocchera, SM Reeve, S Keshipeddy, MN Lombardo, B Hajian, ... ACS medicinal chemistry letters 7 (7), 692-696, 2016 | 34 | 2016 |
Dual modifications of α-galactosylceramide synergize to promote activation of human invariant natural killer T cells and stimulate anti-tumor immunity D Chennamadhavuni, NA Saavedra-Avila, LJ Carreño, ... Cell chemical biology 25 (5), 571-584. e8, 2018 | 31 | 2018 |
Charged propargyl-linked antifolates reveal mechanisms of antifolate resistance and inhibit trimethoprim-resistant MRSA strains possessing clinically relevant mutations SM Reeve, E Scocchera, JJ Ferreira, N G-Dayanandan, S Keshipeddy, ... Journal of medicinal chemistry 59 (13), 6493-6500, 2016 | 29 | 2016 |
High‐mobility‐group protein 2 regulated by microRNA‐127 and small heterodimer partner modulates pluripotency of mouse embryonic stem cells and liver tumor initiating cells Y Zhao, Z Yang, J Wu, R Wu, SK Keshipeddy, D Wright, L Wang Hepatology communications 1 (8), 816-830, 2017 | 25 | 2017 |
MRSA isolates from united states hospitals carry dfrg and dfrk resistance genes and succumb to propargyl-linked antifolates SM Reeve, EW Scocchera, G Narendran, S Keshipeddy, J Krucinska, ... Cell chemical biology 23 (12), 1458-1467, 2016 | 24 | 2016 |
Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis B Hajian, E Scocchera, S Keshipeddy, N G-Dayanandan, C Shoen, ... PloS one 11 (8), e0161740, 2016 | 22 | 2016 |
Amide-Linked C4 ″-saccharide modification of KRN7000 provides potent stimulation of human invariant NKT cells and anti-tumor immunity in a humanized mouse model NA Saavedra-Avila, S Keshipeddy, MJ Guberman-Pfeffer, ... ACS chemical biology 15 (12), 3176-3186, 2020 | 8 | 2020 |
Spindle assembly disruption and cancer cell apoptosis with a CLTC-binding compound MJ Bond, M Bleiler, LE Harrison, EW Scocchera, M Nakanishi, ... Molecular Cancer Research 16 (9), 1361-1372, 2018 | 8 | 2018 |
Silicon acceleration of a tandem alkene isomerization/electrocyclic ring-opening of 2-methyleneoxetanes to α, β-unsaturated methylketones E Farber, A Rudnitskaya, S Keshipeddy, KS Lao, JA Gascon, AR Howell The Journal of Organic Chemistry 78 (22), 11213-11220, 2013 | 8 | 2013 |
Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus S Wang, SM Reeve, GT Holt, AA Ojewole, MS Frenkel, P Gainza, ... PLoS computational biology 18 (2), e1009855, 2022 | 7 | 2022 |
Structure-guided in vitro to in vivo pharmacokinetic optimization of propargyl-linked antifolates MN Lombardo, N G-Dayanandan, S Keshipeddy, W Zhou, D Si, ... Drug Metabolism and Disposition 47 (9), 995-1003, 2019 | 7 | 2019 |