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Santosh Keshipeddy
Santosh Keshipeddy
IDEAYA Biosciences
Verified email at ideayabio.com
Title
Cited by
Cited by
Year
Efficient chiral monophosphorus ligands for asymmetric Suzuki–Miyaura coupling reactions
W Tang, ND Patel, G Xu, X Xu, J Savoie, S Ma, MH Hao, S Keshipeddy, ...
Organic letters 14 (9), 2258-2261, 2012
1672012
A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells
KS Wun, G Cameron, O Patel, SS Pang, DG Pellicci, LC Sullivan, ...
Immunity 34 (3), 327-339, 2011
1322011
Efficient monophosphorus ligands for palladium-catalyzed Miyaura borylation
W Tang, S Keshipeddy, Y Zhang, X Wei, J Savoie, ND Patel, NK Yee, ...
Organic Letters 13 (6), 1366-1369, 2011
1282011
Adaptability of the semi‐invariant natural killer T‐cell receptor towards structurally diverse CD1d‐restricted ligands
WC Florence, C Xia, LE Gordy, W Chen, Y Zhang, J Scott‐Browne, ...
The EMBO journal 28 (22), 3579-3590, 2009
552009
Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata
N G-Dayanandan, JL Paulsen, K Viswanathan, S Keshipeddy, ...
Journal of Medicinal Chemistry 57 (6), 2643-2656, 2014
442014
Atypical natural killer T-cell receptor recognition of CD1d–lipid antigens
J Le Nours, T Praveena, DG Pellicci, NA Gherardin, FJ Ross, RT Lim, ...
Nature communications 7 (1), 10570, 2016
402016
Human and mouse type I natural killer T cell antigen receptors exhibit different fine specificities for CD1d-antigen complex
KS Wun, F Ross, O Patel, GS Besra, SA Porcelli, SK Richardson, ...
Journal of Biological Chemistry 287 (46), 39139-39148, 2012
402012
Nonracemic Antifolates Stereoselectively Recruit Alternate Cofactors and Overcome Resistance in S. aureus
S Keshipeddy, SM Reeve, AC Anderson, DL Wright
Journal of the American Chemical Society 137 (28), 8983-8990, 2015
392015
Toward a formal synthesis of laureatin: unexpected rearrangements involving cyclic ether nucleophiles
S Keshipeddy, I Martı́nez, BF Castillo, MD Morton, AR Howell
The Journal of Organic Chemistry 77 (18), 7883-7890, 2012
372012
Charged nonclassical antifolates with activity against gram-positive and gram-negative pathogens
E Scocchera, SM Reeve, S Keshipeddy, MN Lombardo, B Hajian, ...
ACS medicinal chemistry letters 7 (7), 692-696, 2016
342016
Dual modifications of α-galactosylceramide synergize to promote activation of human invariant natural killer T cells and stimulate anti-tumor immunity
D Chennamadhavuni, NA Saavedra-Avila, LJ Carreño, ...
Cell chemical biology 25 (5), 571-584. e8, 2018
312018
Charged propargyl-linked antifolates reveal mechanisms of antifolate resistance and inhibit trimethoprim-resistant MRSA strains possessing clinically relevant mutations
SM Reeve, E Scocchera, JJ Ferreira, N G-Dayanandan, S Keshipeddy, ...
Journal of medicinal chemistry 59 (13), 6493-6500, 2016
292016
High‐mobility‐group protein 2 regulated by microRNA‐127 and small heterodimer partner modulates pluripotency of mouse embryonic stem cells and liver tumor initiating cells
Y Zhao, Z Yang, J Wu, R Wu, SK Keshipeddy, D Wright, L Wang
Hepatology communications 1 (8), 816-830, 2017
252017
MRSA isolates from united states hospitals carry dfrg and dfrk resistance genes and succumb to propargyl-linked antifolates
SM Reeve, EW Scocchera, G Narendran, S Keshipeddy, J Krucinska, ...
Cell chemical biology 23 (12), 1458-1467, 2016
242016
Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis
B Hajian, E Scocchera, S Keshipeddy, N G-Dayanandan, C Shoen, ...
PloS one 11 (8), e0161740, 2016
222016
Amide-Linked C4 ″-saccharide modification of KRN7000 provides potent stimulation of human invariant NKT cells and anti-tumor immunity in a humanized mouse model
NA Saavedra-Avila, S Keshipeddy, MJ Guberman-Pfeffer, ...
ACS chemical biology 15 (12), 3176-3186, 2020
82020
Spindle assembly disruption and cancer cell apoptosis with a CLTC-binding compound
MJ Bond, M Bleiler, LE Harrison, EW Scocchera, M Nakanishi, ...
Molecular Cancer Research 16 (9), 1361-1372, 2018
82018
Silicon acceleration of a tandem alkene isomerization/electrocyclic ring-opening of 2-methyleneoxetanes to α, β-unsaturated methylketones
E Farber, A Rudnitskaya, S Keshipeddy, KS Lao, JA Gascon, AR Howell
The Journal of Organic Chemistry 78 (22), 11213-11220, 2013
82013
Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus
S Wang, SM Reeve, GT Holt, AA Ojewole, MS Frenkel, P Gainza, ...
PLoS computational biology 18 (2), e1009855, 2022
72022
Structure-guided in vitro to in vivo pharmacokinetic optimization of propargyl-linked antifolates
MN Lombardo, N G-Dayanandan, S Keshipeddy, W Zhou, D Si, ...
Drug Metabolism and Disposition 47 (9), 995-1003, 2019
72019
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