Molecules that target beta‐amyloid CI Stains, K Mondal, I Ghosh ChemMedChem: Chemistry Enabling Drug Discovery 2 (12), 1674-1692, 2007 | 157 | 2007 |
Nebraska Red: a phosphinate-based near-infrared fluorophore scaffold for chemical biology applications X Zhou, R Lai, JR Beck, H Li, CI Stains Chemical Communications 52 (83), 12290-12293, 2016 | 135 | 2016 |
Direct detection of double-stranded DNA: molecular methods and applications for DNA diagnostics I Ghosh, CI Stains, AT Ooi, DJ Segal Molecular BioSystems 2 (11), 551-560, 2006 | 133 | 2006 |
DNA sequence-enabled reassembly of the green fluorescent protein CI Stains, JR Porter, AT Ooi, DJ Segal, I Ghosh Journal of the American Chemical Society 127 (31), 10782-10783, 2005 | 123 | 2005 |
A general and rapid cell-free approach for the interrogation of protein− protein, protein− DNA, and protein− RNA interactions and their antagonists utilizing split-protein … JR Porter, CI Stains, BW Jester, I Ghosh Journal of the American Chemical Society 130 (20), 6488-6497, 2008 | 98 | 2008 |
Site-specific detection of DNA methylation utilizing mCpG-SEER CI Stains, JL Furman, DJ Segal, I Ghosh Journal of the American Chemical Society 128 (30), 9761-9765, 2006 | 98 | 2006 |
973. SEquence-Enabled Reassembly of β-Lactamase (SEER-LAC): A Sensitive Method for the Detection of Double-Stranded DNA AT Ooi, CI Stains, I Ghosh, DJ Segal Molecular Therapy 13, S374, 2006 | 89 | 2006 |
Chemoselective alteration of fluorophore scaffolds as a strategy for the development of ratiometric chemodosimeters X Zhou, L Lesiak, R Lai, JR Beck, J Zhao, CG Elowsky, H Li, CI Stains Angewandte Chemie International Edition 56 (15), 4197-4200, 2017 | 64 | 2017 |
Self-assembling NanoLuc luciferase fragments as probes for protein aggregation in living cells J Zhao, TJ Nelson, Q Vu, T Truong, CI Stains ACS chemical biology 11 (1), 132-138, 2016 | 63 | 2016 |
Split β-lactamase sensor for the sequence-specific detection of DNA methylation JR Porter, CI Stains, DJ Segal, I Ghosh Analytical chemistry 79 (17), 6702-6708, 2007 | 62 | 2007 |
Inhibition of β-amyloid fibrillization by directed evolution of a β-sheet presenting miniature protein TJ Smith, CI Stains, SC Meyer, I Ghosh Journal of the American Chemical Society 128 (45), 14456-14457, 2006 | 59 | 2006 |
Identification of fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration M Ambati, I Apicella, S Wang, S Narendran, H Leung, F Pereira, ... Proceedings of the National Academy of Sciences 118 (41), e2102975118, 2021 | 48 | 2021 |
Toward a general approach for RNA-templated hierarchical assembly of split-proteins JL Furman, AH Badran, O Ajulo, JR Porter, CI Stains, DJ Segal, I Ghosh Journal of the American Chemical Society 132 (33), 11692-11701, 2010 | 45 | 2010 |
The 8-silyloxyquinoline scaffold as a versatile platform for the sensitive detection of aqueous fluoride X Zhou, R Lai, H Li, CI Stains Analytical chemistry 87 (8), 4081-4086, 2015 | 44 | 2015 |
Interrogating signaling nodes involved in cellular transformations using kinase activity probes CI Stains, NC Tedford, TC Walkup, E Luković, BN Goguen, LG Griffith, ... Chemistry & biology 19 (2), 210-217, 2012 | 41 | 2012 |
Phosphinate-containing rhodol and fluorescein scaffolds for the development of bioprobes N Gillian Chemical communications 55 (42), 5962-5965, 2019 | 40 | 2019 |
A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly CI Stains, JL Furman, JR Porter, S Rajagopal, Y Li, RT Wyatt, I Ghosh ACS chemical biology 5 (10), 943-952, 2010 | 40 | 2010 |
A p38α-selective chemosensor for use in unfractionated cell lysates CI Stains, E Lukovic, B Imperiali ACS chemical biology 6 (1), 101-105, 2011 | 36 | 2011 |
Interrogating endogenous protein phosphatase activity with rationally designed chemosensors JR Beck, A Lawrence, AS Tung, EN Harris, CI Stains ACS chemical biology 11 (1), 284-290, 2016 | 29 | 2016 |
Cell free methods for detecting protein-ligand binding I Ghosh, CI Stains, JR Porter, B Jester, J Furman US Patent 8,241,860, 2012 | 23 | 2012 |