Recent advances toward a molecular mechanism of efflux pump inhibition TJ Opperman, ST Nguyen Frontiers in microbiology 6, 140720, 2015 | 284 | 2015 |
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives H Sjuts, AV Vargiu, SM Kwasny, ST Nguyen, HS Kim, X Ding, AR Ornik, ... Proceedings of the National Academy of Sciences 113 (13), 3509-3514, 2016 | 207 | 2016 |
A model for a umuDC-dependent prokaryotic DNA damage checkpoint T Opperman, S Murli, BT Smith, GC Walker Proceedings of the National Academy of Sciences 96 (16), 9218-9223, 1999 | 203 | 1999 |
Characterization of a novel pyranopyridine inhibitor of the AcrAB efflux pump of Escherichia coli TJ Opperman, SM Kwasny, HS Kim, ST Nguyen, C Houseweart, ... Antimicrobial agents and chemotherapy 58 (2), 722-733, 2014 | 202 | 2014 |
Static biofilm cultures of Gram‐positive pathogens grown in a microtiter format used for anti‐biofilm drug discovery SM Kwasny, TJ Opperman Current protocols in pharmacology 50 (1), 13A. 8.1-13A. 8.23, 2010 | 175 | 2010 |
Molecular mechanism of MBX2319 inhibition of Escherichia coli AcrB multidrug efflux pump and comparison with other inhibitors AV Vargiu, P Ruggerone, TJ Opperman, ST Nguyen, H Nikaido Antimicrobial agents and chemotherapy 58 (10), 6224-6234, 2014 | 163 | 2014 |
Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics L Doucette-Stamm, D Bush, Q Zeng, T Opperman, CE Houseweart US Patent 6,699,703, 2004 | 155 | 2004 |
The Escherichia coli SOS mutagenesis proteins UmuD and UmuD′ interact physically with the replicative DNA polymerase MD Sutton, T Opperman, GC Walker Proceedings of the National Academy of Sciences 96 (22), 12373-12378, 1999 | 124 | 1999 |
Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium X Wang-Kan, JMA Blair, B Chirullo, J Betts, RM La Ragione, A Ivens, ... MBio 8 (4), 10.1128/mbio. 00968-17, 2017 | 114 | 2017 |
Phylogenetic analysis of sequences from diverse bacteria with homology to the Escherichia coli rho gene T Opperman, JP Richardson Journal of bacteriology 176 (16), 5033-5043, 1994 | 101 | 1994 |
Structure–activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors ST Nguyen, SM Kwasny, X Ding, SC Cardinale, CT McCarthy, HS Kim, ... Bioorganic & medicinal chemistry 23 (9), 2024-2034, 2015 | 88 | 2015 |
Dimerization of the UmuD'protein in solution and its implications for regulation of SOS mutagenesis. AE Ferentz, T Opperman, GC Walker, G Wagner Nature structural biology 4 (12), 979-983, 1997 | 78 | 1997 |
Aryl rhodanines specifically inhibit staphylococcal and enterococcal biofilm formation TJ Opperman, SM Kwasny, JD Williams, AR Khan, NP Peet, DT Moir, ... Antimicrobial agents and chemotherapy 53 (10), 4357-4367, 2009 | 72 | 2009 |
A Role for the umuDC Gene Products ofEscherichia coli in Increasing Resistance to DNA Damage in Stationary Phase by Inhibiting the Transition to Exponential … S Murli, T Opperman, BT Smith, GC Walker Journal of bacteriology 182 (4), 1127-1135, 2000 | 64 | 2000 |
Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics L Doucette-Stamm, D Bush, Q Zeng, T Opperman, CE Houseweart US Patent 7,378,514, 2008 | 63 | 2008 |
Nucleic acid and amino acid sequences relating to streptococcus pneumoniae for diagnostics and therapeutics L Doucette-Stamm, D Bush, Q Zeng, T Opperman, C Houseweart US Patent App. 11/524,787, 2007 | 63 | 2007 |
Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics L Doucette-Stamm, D Bush, Q Zeng, T Opperman, CE Houseweart US Patent 7,893,230, 2011 | 61 | 2011 |
Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics L Doucette-Stamm, D Bush, Q Zeng, T Opperman, CE Houseweart US Patent 7,151,171, 2006 | 58 | 2006 |
Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics L Doucette-Stamm, D Bush, Q Zeng, T Opperman, CE Houseweart US Patent 7,098,023, 2006 | 58 | 2006 |
Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics L Doucette-Stamm, D Bush, Q Zeng, T Opperman, CE Houseweart US Patent 7,626,000, 2009 | 56 | 2009 |