Combretastatin family member OXI4503 induces tumor vascular collapse through the induction of endothelial apoptosis Y Sheng, J Hua, KG Pinney, CM Garner, RR Kane, JA Prezioso, ... International journal of cancer 111 (4), 604-610, 2004 | 105 | 2004 |
Oxi4503, a novel vascular targeting agent: effects on blood flow and antitumor activity in comparison to combretastatin A-4 phosphate. J Hua, Y Sheng, KG Pinney, CM Garner, RR Kane, JA Prezioso, GR Pettit, ... Anticancer research 23 (2B), 1433-1440, 2003 | 97 | 2003 |
Novel Vaccine Adjuvants Based on Targeting Adjuvants to Antibodies Directly to Antigen-Presenting Cells G Zurawski, JF Banchereau, AL Flamar, RR Kane US Patent App. 13/415,564, 2012 | 70 | 2012 |
Toward a cancer therapy with boron-rich oligomeric phosphate diesters that target the cell nucleus A Nakanishi, L Guan, RR Kane, H Kasamatsu, MF Hawthorne Proceedings of the National Academy of Sciences 96 (1), 238-241, 1999 | 66 | 1999 |
Automated syntheses of carborane-derived homogeneous oligophosphates: reagents for use in the immunoprotein-mediated boron neutron capture therapy (BNCT) of cancer RR Kane, K Drechsel, MF Hawthorne Journal of the American Chemical Society 115 (19), 8853-8854, 1993 | 58 | 1993 |
Expeditious synthesis of a key C9–C21 subunit of the aplyslatoxine and oscillatoxins RD Walkup, RR Kane, PD Boatman Jr, RT Cunningham Tetrahedron letters 31 (52), 7587-7590, 1990 | 57 | 1990 |
Synthesis and Structural Characterization of [Me3NH][nido-9, 11-I2-7, 8-C2B9H10] and [Me3NH][nido-9-I-7, 8-C2B9H11] RH Pak, RR Kane, CB Knobler, MF Hawthorne Inorganic Chemistry 33 (23), 5355-5357, 1994 | 54 | 1994 |
Synthesis, in vitro, and in vivo evaluation of phosphate ester derivatives of combretastatin A-4 MB Hadimani, J Hua, MD Jonklaas, RJ Kessler, Y Sheng, A Olivares, ... Bioorganic & medicinal chemistry letters 13 (9), 1505-1508, 2003 | 50 | 2003 |
Preparation and properties of nido-carborane-specific monoclonal antibodies for potential use in boron neutron capture therapy for cancer. RH Pak, FJ Primus, KJ Rickard-Dickson, LL Ng, RR Kane, MF Hawthorne Proceedings of the National Academy of Sciences 92 (15), 6986-6990, 1995 | 49 | 1995 |
Functionalized stilbene derivatives as improved vascular targeting agents DJ Chaplin, CM Garner III, RR Kane, KG Pinney, JA Prezioso, ... US Patent 6,919,324, 2005 | 48 | 2005 |
Efficient Asymmetric Synthesis of the C9−C21 Portion of the Aplysiatoxin and Oscillatoxin Marine Natural Products RD Walkup, JD Kahl, RR Kane The Journal of Organic Chemistry 63 (24), 9113-9116, 1998 | 48 | 1998 |
Synthesis and characterization of oligomeric nido-carboranyl phosphate diester conjugates to antibody and antibody fragments for potential use in boron neutron capture therapy … CJ Chen, RR Kane, FJ Primus, G Szalai, MF Hawthorne, JE Shively Bioconjugate Chemistry 5 (6), 557-564, 1994 | 42 | 1994 |
Solution-phase segment synthesis of boron-rich peptides RR Kane, RH Pak, MF Hawthorne The Journal of Organic Chemistry 58 (5), 991-992, 1993 | 39 | 1993 |
A stereoselective route to the spirobicyclic ring system of oscillatoxin D RD Walkup, PD Boatman Jr, RR Kane, RT Cunningham Tetrahedron letters 32 (32), 3937-3940, 1991 | 39 | 1991 |
Homogeneous immunoconjugates for boron neutron-capture therapy: design, synthesis, and preliminary characterization L Guan, LA Wims, RR Kane, MB Smuckler, SL Morrison, MF Hawthorne Proceedings of the National Academy of Sciences 95 (22), 13206-13210, 1998 | 37 | 1998 |
Bispecific antibody mediated targeting of nido-carboranes to human colon carcinoma cells FJ Primus, RH Pak, KJ Rickard-Dickson, G Szalai, JL Bolen, RR Kane, ... Bioconjugate chemistry 7 (5), 532-535, 1996 | 37 | 1996 |
Synthesis of new building blocks for boron-rich oligomers in boron neutron capture therapy (BNCT). I. K Drechsel, CS Lee, EW Leung, RR Kane, MF Hawthorne Tetrahedron letters 35 (34), 6217-6220, 1994 | 34 | 1994 |
Synthesis and Structure of the Polyhedral [μ-B20H17OH]2- Borane Anion Containing Both Oxygen- and Hydrogen-Bridge Bonds F Li, K Shelly, RR Kane, CB Knobler, MF Hawthorne Journal of the American Chemical Society 118 (27), 6506-6507, 1996 | 32 | 1996 |
An α-alkylation/reduction of ketones via radical cyclizations of β-chloroethylsilyl enol ethers RD Walkup, RR Kane, NU Obeyesekere Tetrahedron letters 31 (11), 1531-1534, 1990 | 30 | 1990 |
Ex-vivo generation of drug-eluting islets improves transplant outcomes by inhibiting TLR4-Mediated NFkB upregulation CA Chang, B Akinbobuyi, JM Quintana, G Yoshimatsu, B Naziruddin, ... Biomaterials 159, 13-24, 2018 | 29 | 2018 |