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Melanie Abongwa
Melanie Abongwa
Toxicologist, Biogen
Verified email at biogen.com
Title
Cited by
Cited by
Year
A brief review on the mode of action of antinematodal drugs
M Abongwa, RJ Martin, AP Robertson
Acta veterinaria 67 (2), 137-152, 2017
1602017
Selective activity of extracts of Margaritaria discoidea and Homalium africanum on Onchocerca ochengi
F Cho-Ngwa, M Abongwa, MN Ngemenya, KD Nyongbela
BMC complementary and alternative medicine 10, 1-7, 2010
1002010
Investigation of acetylcholine receptor diversity in a nematode parasite leads to characterization of tribendimidine-and derquantel-sensitive nAChRs
SK Buxton, CL Charvet, C Neveu, J Cabaret, J Cortet, N Peineau, ...
PLoS pathogens 10 (1), e1003870, 2014
632014
Pharmacological profile of Ascaris suum ACR‐16, a new homomeric nicotinic acetylcholine receptor widely distributed in Ascaris tissues
M Abongwa, SK Buxton, E Courtot, CL Charvet, C Neveu, CJ McCoy, ...
British Journal of Pharmacology 173 (16), 2463-2477, 2016
432016
The Ascaris suum nicotinic receptor, ACR-16, as a drug target: four novel negative allosteric modulators from virtual screening
F Zheng, AP Robertson, M Abongwa, WY Edward, RJ Martin
International Journal for Parasitology: Drugs and Drug Resistance 6 (1), 60-73, 2016
242016
Curiouser and curiouser: The macrocyclic lactone, abamectin, is also a potent inhibitor of pyrantel/tribendimidine nicotinic acetylcholine receptors of gastro-intestinal worms
M Abongwa, SK Buxton, AP Robertson, RJ Martin
PLoS One 11 (1), e0146854, 2016
222016
Menthol acts as a positive allosteric modulator on nematode levamisole sensitive nicotinic acetylcholine receptors
S Choudhary, DS Marjianović, CR Wong, X Zhang, M Abongwa, JR Coats, ...
International Journal for Parasitology: Drugs and Drug Resistance 9, 44-53, 2019
152019
Monepantel is a non-competitive antagonist of nicotinic acetylcholine receptors from Ascaris suum and Oesophagostomum dentatum
M Abongwa, DS Marjanovic, JG Tipton, F Zheng, RJ Martin, SM Trailovic, ...
International Journal for Parasitology: Drugs and Drug Resistance 8 (1), 36-42, 2018
152018
Pharmacological characterization of a homomeric nicotinic acetylcholine receptor formed by Ancylostoma caninum ACR-16
S Choudhary, JG Tipton, M Abongwa, MT Brewer, JJ Chelladurai, ...
Invertebrate Neuroscience 19, 1-10, 2019
132019
The cholinomimetic morantel as an open channel blocker of the Ascaris suum ACR-16 nAChR
M Abongwa, KE Baber, RJ Martin, AP Robertson
Invertebrate Neuroscience 16, 1-7, 2016
82016
Filaricidal activity of Daniellia oliveri and Psorospermum febrifugum extracts
M Abongwa, M Samje, GA Ayimele, SB Babiaka, C Bulman, J Sakanari, ...
Parasites & Vectors 14, 1-15, 2021
72021
Anthelmintics: the best way to predict the future is to create it
RJ Martin, S Verma, S Choudhary, S Kashyap, M Abongwa, F Zheng, ...
Veterinary Parasitology 212 (1-2), 18-24, 2015
52015
Efficacy of Senna occidentalis in the amelioration of tetracycline induced hepato-and nephro-toxicities in rabbits
M Abongwa, AG Rageh, O Arowolo, C Dawurung, O Oladipo, A Atiku, ...
Toxicology Letters, S207, 2010
42010
Nodulisporic acid produces direct activation and positive allosteric modulation of AVR-14B, a glutamate-gated chloride channel from adult Brugia malayi
S Choudhary, M Abongwa, SS Kashyap, S Verma, GR Mair, D Kulke, ...
Proceedings of the National Academy of Sciences 119 (34), e2111932119, 2022
22022
Potential new drug targets and therapeutic approaches for parasitic nematode infections
M Abongwa
Iowa State University, 2017
22017
Functional expression of a glutamate-gated chloride channel (GLC-3) from adult Brugia malayi.
B Akanji, M Abongwa, R Martin, A Robertson
12018
A paper published in the International Journal for Parasitology: Drugs and Drug Resistance (2019)
S Choudhary, DS Marjianović, CR Wong, X Zhang, M Abongwa, JR Coats, ...
Identification and modulation of novel nicotinic acetylcholine receptors …, 2019
2019
Pharmacological characterization of a homomeric nicotinic acetylcholine receptor formed by Ancylostoma caninum ACR-16
N Musselman
2018
ACTIVITY OF CRUDE EXTRACTS AND CHROMATOGRAPHIC FRACTIONS OF DANIELLIA OLIVERI AND PSOROSPERMUM FEBRIFUGUM AGAINST ADULT BRUGIA PAHANGI
M Abongwa, F Cho-Ngwa, G Ayimele, M Samje, SB Babiaka, J Sakanari, ...
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 95 (5), 152-152, 2017
2017
The Ascaris suum nicotinic receptor, ACR-16, as a drug target: four novel negative allosteric modulators from virtual screening.
ZFD Zheng FuDan, AP Robertson, M Abongwa, EW Yu, RJ Martin
2016
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