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David Carling
David Carling
MRC Clinical Sciences Centre
Verified email at imperial.ac.uk
Title
Cited by
Cited by
Year
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
T Yamauchi, J Kamon, Y Minokoshi, Y Ito, H Waki, S Uchida, S Yamashita, ...
Nature medicine 8 (11), 1288-1295, 2002
56352002
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism
BB Kahn, T Alquier, D Carling, DG Hardie
Cell metabolism 1 (1), 15-25, 2005
34482005
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
Y Minokoshi, YB Kim, OD Peroni, LGD Fryer, C Müller, D Carling, ...
Nature 415 (6869), 339-343, 2002
25942002
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade
A Woods, SR Johnstone, K Dickerson, FC Leiper, LGD Fryer, D Neumann, ...
Current biology 13 (22), 2004-2008, 2003
19652003
The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?
DG Hardie, D Carling, M Carlson
Annual review of biochemistry 67 (1), 821-855, 1998
18461998
The AMP‐activated protein kinase: fuel gauge of the mammalian cell?
DG Hardie, D Carling
European journal of biochemistry 246 (2), 259-273, 1997
16961997
Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells
A Woods, K Dickerson, R Heath, SP Hong, M Momcilovic, SR Johnstone, ...
Cell metabolism 2 (1), 21-33, 2005
16082005
Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated …
SA Hawley, M Davison, A Woods, SP Davies, RK Beri, D Carling, ...
Journal of Biological Chemistry 271 (44), 27879-27887, 1996
15001996
The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism
G Frost, ML Sleeth, M Sahuri-Arisoylu, B Lizarbe, S Cerdan, L Brody, ...
Nature communications 5 (1), 3611, 2014
14942014
The AMP-activated protein kinase cascade–a unifying system for energy control
D Carling
Trends in biochemical sciences 29 (1), 18-24, 2004
13982004
The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways
LGD Fryer, A Parbu-Patel, D Carling
Journal of Biological Chemistry 277 (28), 25226-25232, 2002
12792002
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
C Selman, JMA Tullet, D Wieser, E Irvine, SJ Lingard, AI Choudhury, ...
Science 326 (5949), 140-144, 2009
12352009
Structure of mammalian AMPK and its regulation by ADP
B Xiao, MJ Sanders, E Underwood, R Heath, FV Mayer, D Carmena, ...
Nature 472 (7342), 230-233, 2011
10722011
Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
AS Marsin, L Bertrand, MH Rider, J Deprez, C Beauloye, MF Vincent, ...
Current biology 10 (20), 1247-1255, 2000
10092000
Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism
TAJ Haystead, ATR Sim, D Carling, RC Honnor, Y Tsukitani, P Cohen, ...
Nature 337 (6202), 78-81, 1989
9971989
AMP-activated protein kinase plays a role in the control of food intake
U Andersson, K Filipsson, CR Abbott, A Woods, K Smith, SR Bloom, ...
Journal of Biological Chemistry 279 (13), 12005-12008, 2004
9542004
AMPK, insulin resistance, and the metabolic syndrome
NB Ruderman, D Carling, M Prentki, JM Cacicedo
The Journal of clinical investigation 123 (7), 2764-2772, 2013
9332013
Characterization of AMP-activated protein kinase γ-subunit isoforms and their role in AMP binding
PCF CHEUNG, IP SALT, SP DAVIES, DG HARDIE, D CARLING
Biochemical Journal 346 (3), 659-669, 2000
8292000
Adenosine 5′-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype
D Sag, D Carling, RD Stout, J Suttles
The Journal of Immunology 181 (12), 8633-8641, 2008
8192008
Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade
MJ Sanders, PO Grondin, BD Hegarty, MA Snowden, D Carling
Biochemical Journal 403 (1), 139-148, 2007
7732007
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