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Tjakko van Ham
Tjakko van Ham
Erasmus MC, Rotterdam, the Netherlands
Dirección de correo verificada de erasmusmc.nl
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C. elegans Model Identifies Genetic Modifiers of α-Synuclein Inclusion Formation During Aging
TJ Van Ham, KL Thijssen, R Breitling, RMW Hofstra, RHA Plasterk, ...
PLoS genetics 4 (3), e1000027, 2008
4652008
Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration
TM Tsarouchas, D Wehner, L Cavone, T Munir, M Keatinge, M Lambertus, ...
Nature communications 9 (1), 4670, 2018
2132018
Homozygous mutations in CSF1R cause a pediatric-onset leukoencephalopathy and can result in congenital absence of microglia
N Oosterhof, IJ Chang, EG Karimiani, LE Kuil, DM Jensen, R Daza, ...
The American Journal of Human Genetics 104 (5), 936-947, 2019
1922019
Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity
TJ van Ham, MA Holmberg, AT van der Goot, E Teuling, ...
Cell 142 (4), 601-612, 2010
1752010
Live imaging of apoptotic cells in zebrafish
TJ van Ham, J Mapes, D Kokel, RT Peterson
The FASEB Journal 24 (11), 4336, 2010
1472010
Identification of nonvisual photomotor response cells in the vertebrate hindbrain
D Kokel, TW Dunn, MB Ahrens, R Alshut, CYJ Cheung, L Saint-Amant, ...
Journal of Neuroscience 33 (9), 3834-3843, 2013
1312013
Chaperone proteostasis in Parkinson's disease: Stabilization of the Hsp70/α‐synuclein complex by Hip
C Roodveldt, CW Bertoncini, A Andersson, AT Van Der Goot, ST Hsu, ...
The EMBO journal 28 (23), 3758-3770, 2009
1302009
Colony-stimulating factor 1 receptor (CSF1R) regulates microglia density and distribution, but not microglia differentiation in vivo
N Oosterhof, LE Kuil, HC van der Linde, SM Burm, W Berdowski, ...
Cell reports 24 (5), 1203-1217. e6, 2018
1232018
A FRET sensor for non‐invasive imaging of amyloid formation in vivo
GS Kaminski Schierle, CW Bertoncini, FTS Chan, AT Van Der Goot, ...
ChemPhysChem 12 (3), 673-680, 2011
1222011
Neurodegenerative diseases: lessons from genome‐wide screens in small model organisms
TJ Van Ham, R Breitling, MA Swertz, EAA Nollen
EMBO molecular medicine 1 (8‐9), 360-370, 2009
1052009
Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis
MI Cunha, M Su, L Cantuti-Castelvetri, SA Müller, M Schifferer, ...
Journal of Experimental Medicine 217 (5), 2020
1012020
Towards multiparametric fluorescent imaging of amyloid formation: studies of a YFP model of α-synuclein aggregation
TJ van Ham, A Esposito, JR Kumita, STD Hsu, GSK Schierle, CF Kaminski, ...
Journal of molecular biology 395 (3), 627-642, 2010
892010
A small molecule that induces intrinsic pathway apoptosis with unparalleled speed
R Palchaudhuri, MJ Lambrecht, RC Botham, KC Partlow, TJ Van Ham, ...
Cell reports 13 (9), 2027-2036, 2015
862015
Apoptotic cells are cleared by directional migration and elmo1-dependent macrophage engulfment
TJ van Ham, D Kokel, RT Peterson
Current Biology 22 (9), 830-836, 2012
862012
Whole exome sequencing coupled with unbiased functional analysis reveals new Hirschsprung disease genes
H Gui, D Schriemer, WW Cheng, RK Chauhan, G Antiňolo, C Berrios, ...
Genome biology 18, 1-13, 2017
822017
Identification of a conserved and acute neurodegeneration‐specific microglial transcriptome in the zebrafish
N Oosterhof, IR Holtman, LE Kuil, HC van der Linde, EWGM Boddeke, ...
Glia 65 (1), 138-149, 2017
822017
Intravital correlated microscopy reveals differential macrophage and microglial dynamics during resolution of neuroinflammation
TJ van Ham, CA Brady, RD Kalicharan, N Oosterhof, J Kuipers, ...
Disease models & mechanisms 7 (7), 857-869, 2014
692014
Immune cell dynamics in the CNS: Learning from the zebrafish
N Oosterhof, E Boddeke, TJ van Ham
Glia 63 (5), 719-735, 2015
572015
FLIPPER, a combinatorial probe for correlated live imaging and electron microscopy, allows identification and quantitative analysis of various cells and organelles
J Kuipers, TJ van Ham, RD Kalicharan, A Veenstra-Algra, KA Sjollema, ...
Cell and tissue research 360 (1), 61-70, 2015
512015
Loss of UGP2 in brain leads to a severe epileptic encephalopathy, emphasizing that bi-allelic isoform-specific start-loss mutations of essential genes can cause genetic diseases
E Perenthaler, A Nikoncuk, S Yousefi, WM Berdowski, M Alsagob, I Capo, ...
Acta Neuropathologica 139, 415-442, 2020
492020
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