Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography K Mandal, M Uppalapati, D Ault-Riché, J Kenney, J Lowitz, SS Sidhu, ... Proceedings of the National Academy of Sciences 109 (37), 14779-14784, 2012 | 138 | 2012 |
Native chemical ligation at Asx-Cys, Glx-Cys: chemical synthesis and high-resolution X-ray structure of ShK toxin by racemic protein crystallography B Dang, T Kubota, K Mandal, F Bezanilla, SBH Kent Journal of the American Chemical Society 135 (32), 11911-11919, 2013 | 115 | 2013 |
A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo M Uppalapati, DJ Lee, K Mandal, H Li, LP Miranda, J Lowitz, J Kenney, ... ACS chemical biology 11 (4), 1058-1065, 2016 | 99 | 2016 |
Racemic crystallography of synthetic protein enantiomers used to determine the X‐ray structure of plectasin by direct methods K Mandal, BL Pentelute, V Tereshko, V Thammavongsa, O Schneewind, ... Protein Science 18 (6), 1146-1154, 2009 | 97 | 2009 |
Diversity‐Oriented Approach to Biologically Relevant Molecular Frameworks Starting with β‐Naphthol and Using the Claisen Rearrangement and Olefin Metathesis as Key Steps S Kotha, K Mandal, A Tiwari, SM Mobin Chemistry–A European Journal 12 (31), 8024-8038, 2006 | 97 | 2006 |
A one-pot approach to neoglycopeptides using orthogonal native chemical ligation and click chemistry DJ Lee, K Mandal, PWR Harris, MA Brimble, SBH Kent Organic letters 11 (22), 5270-5273, 2009 | 96 | 2009 |
Fully convergent chemical synthesis of ester insulin: determination of the high resolution X-ray structure by racemic protein crystallography M Avital-Shmilovici, K Mandal, ZP Gates, NB Phillips, MA Weiss, ... Journal of the American Chemical Society 135 (8), 3173-3185, 2013 | 89 | 2013 |
Formation of Arenes via Diallylarenes: Strategic Utilization of Suzuki–Miyaura Cross‐Coupling, Claisen Rearrangement and Ring‐Closing Metathesis S Kotha, VR Shah, K Mandal Advanced Synthesis & Catalysis 349 (7), 1159-1172, 2007 | 76 | 2007 |
A Retrospective on the Design and Synthesis of Novel Molecules through a Strategic Consideration of Metathesis and Suzuki–Miyaura Cross‐Coupling S Kotha, K Mandal Chemistry–An Asian Journal 4 (3), 354-362, 2009 | 73 | 2009 |
Metathetic approach to naphthoxepin and spirocyclic molecular frameworks S Kotha, K Mandal Tetrahedron letters 45 (7), 1391-1394, 2004 | 70 | 2004 |
Total chemical synthesis of biologically active vascular endothelial growth factor K Mandal, SBH Kent Angewandte Chemie International Edition 50 (35), 8029-8033, 2011 | 67 | 2011 |
A new protocol for benzoannulation by double Claisen rearrangement and ring-closing metathesis reactions as key steps S Kotha, K Mandal Elsevier, 2004 | 66 | 2004 |
Microwave-assisted Claisen rearrangement on a silica gel support S Kotha, K Mandal, AC Deb, S Banerjee Tetrahedron letters 45 (52), 9603-9605, 2004 | 65 | 2004 |
(Quasi‐) racemic X‐ray structures of glycosylated and non‐glycosylated forms of the chemokine Ser‐CCL1 prepared by total chemical synthesis R Okamoto, K Mandal, MR Sawaya, Y Kajihara, TO Yeates, SBH Kent Angewandte Chemie 126 (20), 5294-5298, 2014 | 59 | 2014 |
Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography BL Pentelute, K Mandal, ZP Gates, MR Sawaya, TO Yeates, SBH Kent Chemical communications 46 (43), 8174-8176, 2010 | 55 | 2010 |
Total chemical synthesis and biological activities of glycosylated and non‐glycosylated forms of the chemokines CCL1 and Ser‐CCL1 R Okamoto, K Mandal, M Ling, AD Luster, Y Kajihara, SBH Kent Angewandte Chemie 126 (20), 5288-5293, 2014 | 53 | 2014 |
Determination of the X‐ray structure of the snake venom protein omwaprin by total chemical synthesis and racemic protein crystallography JR Banigan, K Mandal, MR Sawaya, V Thammavongsa, APA Hendrickx, ... Protein science 19 (10), 1840-1849, 2010 | 50 | 2010 |
A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography RD Bunker, K Mandal, G Bashiri, JJ Chaston, BL Pentelute, JS Lott, ... Proceedings of the National Academy of Sciences 112 (14), 4310-4315, 2015 | 48 | 2015 |
Dynamics of “flap” structures in three HIV-1 protease/inhibitor complexes probed by total chemical synthesis and pulse-EPR spectroscopy VY Torbeev, H Raghuraman, K Mandal, S Senapati, E Perozo, SBH Kent Journal of the American Chemical Society 131 (3), 884-885, 2009 | 47 | 2009 |
Design, total chemical synthesis, and X‐ray structure of a protein having a novel linear‐loop polypeptide chain topology K Mandal, BL Pentelute, D Bang, ZP Gates, VY Torbeev, SBH Kent Angewandte Chemie International Edition 51 (6), 1481-1486, 2012 | 46 | 2012 |