Pharmacological chaperone for α-crystallin partially restores transparency in cataract models LN Makley, KA McMenimen, BT DeVree, JW Goldman, BN McGlasson, ... Science 350 (6261), 674-677, 2015 | 245 | 2015 |
Mapping interactions with the chaperone network reveals factors that protect against tau aggregation SA Mok, C Condello, R Freilich, A Gillies, T Arhar, J Oroz, H Kadavath, ... Nature structural & molecular biology 25 (5), 384-393, 2018 | 134 | 2018 |
Validation of the Hsp70–Bag3 protein–protein interaction as a potential therapeutic target in cancer X Li, T Colvin, JN Rauch, D Acosta-Alvear, M Kampmann, B Dunyak, ... Molecular cancer therapeutics 14 (3), 642-648, 2015 | 134 | 2015 |
Peptidyl-proline isomerases (PPIases): targets for natural products and natural product-inspired compounds: miniperspective BM Dunyak, JE Gestwicki Journal of medicinal chemistry 59 (21), 9622-9644, 2016 | 117 | 2016 |
Apratoxin kills cells by direct blockade of the Sec61 protein translocation channel AO Paatero, J Kellosalo, BM Dunyak, J Almaliti, JE Gestwicki, ... Cell chemical biology 23 (5), 561-566, 2016 | 91 | 2016 |
Stabilizing the Hsp70-Tau complex promotes turnover in models of tauopathy ZT Young, JN Rauch, VA Assimon, UK Jinwal, M Ahn, X Li, BM Dunyak, ... Cell chemical biology 23 (8), 992-1001, 2016 | 71 | 2016 |
High-throughput screen for inhibitors of protein–protein interactions in a reconstituted heat shock protein 70 (Hsp70) complex IR Taylor, BM Dunyak, T Komiyama, H Shao, X Ran, VA Assimon, ... Journal of Biological Chemistry 293 (11), 4014-4025, 2018 | 34 | 2018 |
Mechanism of action of VP1-001 in cryAB (R120G)-associated and age-related cataracts KS Molnar, BM Dunyak, B Su, Y Izrayelit, B McGlasson-Naumann, ... Investigative ophthalmology & visual science 60 (10), 3320-3331, 2019 | 26 | 2019 |
Nano-structures and interactions of alkali metals within silica gel JL Dye, P Nandi, JE Jackson, M Lefenfeld, PA Bentley, BM Dunyak, ... Chemistry of Materials 23 (9), 2388-2397, 2011 | 24 | 2011 |
Rational design and screening of peptide-based inhibitors of heat shock factor 1 (HSF1) X Ran, ET Burchfiel, B Dong, NJ Rettko, BM Dunyak, H Shao, DJ Thiele, ... Bioorganic & medicinal chemistry 26 (19), 5299-5306, 2018 | 15 | 2018 |
Reductive N–O cleavage of Weinreb amides by sodium in alumina and silica gels: synthetic and mechanistic studies JE Jackson, BN O’Brien, SK Kedzior, GR Fryz, FS Jalloh, A Banisafar, ... Tetrahedron letters 56 (45), 6227-6230, 2015 | 13 | 2015 |
Selective targeting of cells via bispecific molecules that exploit coexpression of two intracellular proteins BM Dunyak, RL Nakamura, AD Frankel, JE Gestwicki ACS chemical biology 10 (11), 2441-2447, 2015 | 6 | 2015 |
REM-422, a Potent, Selective, Oral Small Molecule mRNA Degrader of the MYB Oncogene, Demonstrates Anti-Tumor Activity in Mouse Xenograft Models of AML S Prajapati, M Cameron, BM Dunyak, M Shan, YA Siu, S Levin-Furtney, ... Blood 142, 1425, 2023 | 1 | 2023 |
Discovery of non-sterol αB-crystallin ligands as potential cataract therapeutics B Dunyak, B Su, K Molnar, P Hamilton, S Bozeman, S Li, L Liu, UP Andley, ... Investigative Ophthalmology & Visual Science 60 (9), 5691-5691, 2019 | 1 | 2019 |
IPV-containing peptides stabilize mutant αB-crystallin oligomers through conformational rearrangement B Su, B Dunyak, K Molnar, L Makley Investigative Ophthalmology & Visual Science 60 (9), 5692-5692, 2019 | | 2019 |
Peptidyl-Prolyl Isomerases as Promising Targets for Natural Product-Inspired Therapeutics. B Dunyak | | 2016 |