Chemoprevention of 2-acetylaminofluorene-induced hepatotoxicity and lipid peroxidation in rats by kolaviron—a Garcinia kola seed extract EO Farombi, JG Tahnteng, AO Agboola, JO Nwankwo, GO Emerole Food and Chemical Toxicology 38 (6), 535-541, 2000 | 353 | 2000 |
Deubiquitinases (DUBs) and DUB inhibitors: a patent review P Farshi, RR Deshmukh, JO Nwankwo, RT Arkwright, B Cvek, J Liu, ... Expert opinion on therapeutic patents 25 (10), 1191-1208, 2015 | 128 | 2015 |
Identification of a fatty acid Δ6-desaturase deficiency in human skin fibroblasts DE Williard, JO Nwankwo, TL Kaduce, SD Harmon, M Irons, HW Moser, ... Journal of lipid research 42 (4), 501-508, 2001 | 94 | 2001 |
Inhibition of aflatoxin B1 genotoxicity in human liver-derived HepG2 cells by kolaviron biflavonoids and molecular mechanisms of action JO Nwankwo, JG Tahnteng, GO Emerole European Journal of Cancer Prevention, 351-361, 2000 | 88 | 2000 |
Peroxisome proliferator-activated receptor-γ expression in human malignant and normal brain, breast and prostate-derived cells JO Nwankwo, MEC Robbins Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 64 (4-5), 241-245, 2001 | 86 | 2001 |
A nucleotide insertion in the transcriptional regulatory region of FADS2 gives rise to human fatty acid delta-6-desaturase deficiency JO Nwankwo, AA Spector, FE Domann Journal of lipid research 44 (12), 2311-2319, 2003 | 60 | 2003 |
Selenium nanoparticles and metformin ameliorate streptozotocin-instigated brain oxidative-inflammatory stress and neurobehavioral alterations in rats AP Ebokaiwe, S Okori, JO Nwankwo, CECC Ejike, SO Osawe Naunyn-Schmiedeberg's archives of pharmacology 394 (4), 591-602, 2021 | 46 | 2021 |
Anti-nutritional factors, essential and non-essential fatty acids composition of ugba (Pentaclethra macrophylla) seeds at different stages of processing and … VA Onwuliri, I Attah, JO Nwankwo | 41 | 2004 |
Acetaldehyde activates Jun/AP-1 expression and DNA binding activity in human oral keratinocytes SR Timmons, JO Nwankwo, FE Domann Oral oncology 38 (3), 281-290, 2002 | 37 | 2002 |
Possible modulatory effect of browned yam flour diet on chemically-induced toxicity in the rat EO Farombi, JO Nwankwo, GO Emerole Food and chemical toxicology 35 (10-11), 975-979, 1997 | 28 | 1997 |
Anti-metastatic activities of all-trans retinoic acid, indole-3-carbinol and (+)-catechin in Dunning rat invasive prostate adenocarcinoma cells. JO Nwankwo Anticancer research 22 (6C), 4129-4135, 2002 | 25 | 2002 |
Effect of methanolic extract of browned yam flour diet on 7, 12 Dimethylbenzanthracene (DMBA) and 3-methylcholanthrene (3-MC)-induced toxicity in the rat EO Farombi, JO Nwankwo, GO Emerole Proceedings of the Federation of African Society on Biochemistry and …, 1998 | 22 | 1998 |
Enzymatic release of dipeptidyl peptidase‐4 inhibitors (gliptins) from pigeon pea (Cajanus cajan) nutrient reservoir proteins: In silico and in vitro assessments RT Boachie, FL Okoro, K Imai, L Sun, SO Elom, JO Nwankwo, ... Journal of food biochemistry 43 (12), e13071, 2019 | 18 | 2019 |
Induction of chromosomal aberrations, cytotoxicity, and morphological transformation in mammalian cells by the antiparasitic drug flubendazole and the antineoplastic drug … H Nianjun, L Cerepnalkoski, JO Nwankwo, M Dews, JR Landolph Toxicological Sciences 22 (2), 304-313, 1994 | 16 | 1994 |
Chloramphenicol and ampicillin-induced changes in rat hepatic esterase and amidase activities EO Farombi, JO Nwankwo, SH Wara, B Odutola, GO Emerole Bioscience Reports 20, 13-19, 2000 | 15 | 2000 |
The effect of modulation of glutathione levels on markers for Aflatoxin B,-induced cell damage EO Farombi, JO Nwankwo, GO Emerole College of Medicine, 2005 | 14 | 2005 |
Possible chloroquine-induced modification of N-acetylation of isoniazid and sulphadimidine in the rat. JO Nwankwo, MA Garba, CE Chinje, LO Mgbojikwe, GO Emerole | 14 | 1990 |
Imaging and selective retention of phospholipid ether analogs JP Weichert, M Longino, S Weber, JO Nwankwo US Patent 7,632,644, 2009 | 13 | 2009 |
Significant transcriptional down-regulation of the human MDR1 gene by β-naphthoflavone: A proposed hypothesis linking potent CYP gene induction to MDR1 inhibition JO Nwankwo Medical hypotheses 68 (3), 661-669, 2007 | 13 | 2007 |
Nanosized selenium and Loranthus micranthus leaves ameliorate streptozotocin-induced hepato-renal dysfunction in rats via enhancement of antioxidant system, regulation of … AP Ebokaiwe, OM Ijomone, S Griffin, RC Ehiri, KE Obeten, JO Nwankwo, ... Pharmanutrition 9, 100150, 2019 | 9 | 2019 |