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kewei zheng
kewei zheng
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G-quadruplex formation at the 3′ end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase
Q Wang, J Liu, Z Chen, K Zheng, C Chen, Y Hao, Z Tan
Nucleic acids research 39 (14), 6229-6237, 2011
1872011
Molecular crowding creates an essential environment for the formation of stable G-quadruplexes in long double-stranded DNA
K Zheng, Z Chen, Y Hao, Z Tan
Nucleic acids research 38 (1), 327-338, 2010
1552010
Co-transcriptional formation of DNA:RNA hybrid G-quadruplex and potential function as constitutional cis element for transcription control
K Zheng, S Xiao, J Liu, J Zhang, Y Hao, Z Tan
Nucleic acids research 41 (10), 5533-5541, 2013
1412013
Detection of genomic G-quadruplexes in living cells using a small artificial protein
K Zheng, J Zhang, Y He, J Gong, C Wen, J Chen, Y Hao, Y Zhao, Z Tan
Nucleic acids research 48 (20), 11706-11720, 2020
1132020
Guanine-vacancy–bearing G-quadruplexes responsive to guanine derivatives
X Li, K Zheng, J Zhang, H Liu, Y He, B Yuan, Y Hao, Z Tan
Proceedings of the National Academy of Sciences 112 (47), 14581-14586, 2015
1022015
Mechanism and manipulation of DNA: RNA hybrid G-quadruplex formation in transcription of G-rich DNA
J Zhang, K Zheng, S Xiao, Y Hao, Z Tan
Journal of the American Chemical Society 136 (4), 1381-1390, 2014
782014
Reduced or diminished stabilization of the telomere G-quadruplex and inhibition of telomerase by small chemical ligands under molecular crowding condition
Z Chen, K Zheng, Y Hao, Z Tan
Journal of the American Chemical Society 131 (30), 10430-10438, 2009
782009
DNA G-quadruplex formation in response to remote downstream transcription activity: long-range sensing and signal transducing in DNA double helix
C Zhang, H Liu, K Zheng, Y Hao, Z Tan
Nucleic acids research 41 (14), 7144-7152, 2013
752013
A competitive formation of DNA: RNA hybrid G-quadruplex is responsible to the mitochondrial transcription termination at the DNA replication priming site
K Zheng, R Wu, Y He, S Xiao, J Zhang, J Liu, Y Hao, Z Tan
Nucleic acids research 42 (16), 10832-10844, 2014
682014
Bioinformatic analysis reveals an evolutional selection for DNA: RNA hybrid G-quadruplex structures as putative transcription regulatory elements in warm-blooded animals
S Xiao, J Zhang, K Zheng, Y Hao, Z Tan
Nucleic acids research 41 (22), 10379-10390, 2013
672013
Formation of DNA: RNA Hybrid G‐Quadruplex in Bacterial Cells and Its Dominance over the Intramolecular DNA G‐Quadruplex in Mediating Transcription Termination
R Wu, K Zheng, J Zhang, Y Hao, Z Tan
Angewandte Chemie International Edition 54 (8), 2447-2451, 2015
562015
Kinetic and thermodynamic control of G‐quadruplex folding
Y Xue, J Liu, K Zheng, Z Kan, Y Hao, Z Tan
Angewandte Chemie International Edition 50 (35), 8046-8050, 2011
472011
Dissecting the strand folding orientation and formation of G-quadruplexes in single-and double-stranded nucleic acids by ligand-induced photocleavage footprinting
K Zheng, D Zhang, L Zhang, Y Hao, X Zhou, Z Tan
Journal of the American Chemical Society 133 (5), 1475-1483, 2011
392011
Superhelicity constrains a localized and R-loop-dependent formation of G-quadruplexes at the upstream region of transcription
K Zheng, Y He, H Liu, X Li, Y Hao, Z Tan
ACS Chemical Biology 12 (10), 2609-2618, 2017
342017
Formation of DNA: RNA Hybrid G‐Quadruplexes of Two G‐Quartet Layers in Transcription: Expansion of the Prevalence and Diversity of G‐Quadruplexes in Genomes
S Xiao, J Zhang, J Wu, R Wu, Y Xia, K Zheng, Y Hao, X Zhou, Z Tan
Angewandte Chemie 126 (48), 13326-13330, 2014
332014
G-quadruplex structural variations in human genome associated with single-nucleotide variations and their impact on gene activity
J Gong, C Wen, M Tang, R Duan, J Chen, J Zhang, K Zheng, Y He, Y Hao, ...
Proceedings of the National Academy of Sciences 118 (21), e2013230118, 2021
302021
Exceptionally Selective and Tunable Sensing of Guanine Derivatives and Analogues by Structural Complementation in a G‐Quadruplex
X Li, K Zheng, Y Hao, Z Tan
Angewandte Chemie 128 (44), 13963-13968, 2016
302016
Selective targeting of guanine-vacancy-bearing G-quadruplexes by G-quartet complementation and stabilization with a guanine–peptide conjugate
Y He, K Zheng, C Wen, X Li, J Gong, Y Hao, Y Zhao, Z Tan
Journal of the American Chemical Society 142 (26), 11394-11403, 2020
262020
Transmission of dynamic supercoiling in linear and multi-way branched DNAs and its regulation revealed by a fluorescent G-quadruplex torsion sensor
Y Xia, K Zheng, Y He, H Liu, C Wen, Y Hao, Z Tan
Nucleic acids research 46 (14), 7418-7424, 2018
172018
RNA G-quadruplex formation in defined sequence in living cells detected by bimolecular fluorescence complementation
H Liu, K Zheng, Q Chen, Y Hao, Z Tan
Chemical Science 7 (7), 4573-4581, 2016
152016
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