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Aravind Chandrasekaran
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Remarkable structural transformations of actin bundles are driven by their initial polarity, motor activity, crosslinking, and filament treadmilling
A Chandrasekaran, A Upadhyaya, GA Papoian
PLoS computational biology 15 (7), e1007156, 2019
362019
Liquid-like VASP condensates drive actin polymerization and dynamic bundling
K Graham, A Chandrasekaran, L Wang, A Ladak, EM Lafer, P Rangamani, ...
Nature physics 19 (4), 574-585, 2023
252023
Molecular binding sites are located near the interface of intrinsic dynamics domains (IDDs)
H Li, S Sakuraba, A Chandrasekaran, LW Yang
Journal of Chemical Information and Modeling 54 (8), 2275-2285, 2014
232014
Protein dynamics and contact topology reveal protein–DNA binding orientation
A Chandrasekaran, J Chan, C Lim, LW Yang
Journal of Chemical Theory and Computation 12 (11), 5269-5277, 2016
112016
Simulated actin reorganization mediated by motor proteins
MV Ciocanel, A Chandrasekaran, C Mager, Q Ni, GA Papoian, A Dawes
PLoS Computational Biology 18 (4), e1010026, 2022
62022
Segmental Lennard-Jones interactions for semi-flexible polymer networks
C Floyd, A Chandresekaran, H Ni, Q Ni, GA Papoian
Molecular Physics 119 (19-20), e1910358, 2021
62021
Kinetic trapping organizes actin filaments within liquid-like protein droplets
A Chandrasekaran, K Graham, JC Stachowiak, P Rangamani
Nature Communications 15 (1), 3139, 2024
52024
Computational simulations reveal that Abl activity controls cohesiveness of actin networks in growth cones
A Chandrasekaran, A Clarke, P McQueen, HY Fang, GA Papoian, ...
Molecular biology of the cell 33 (11), ar92, 2022
42022
Nucleation causes an actin network to fragment into multiple high-density domains
A Chandrasekaran, E Giniger, GA Papoian
Biophysical Journal 121 (17), 3200-3212, 2022
42022
Liquid-like condensates mediate competition between actin branching and bundling
K Graham, A Chandrasekaran, L Wang, N Yang, EM Lafer, P Rangamani, ...
Proceedings of the National Academy of Sciences 121 (3), e2309152121, 2024
32024
Enabled primarily controls filopodial morphology, not actin organization, in the TSM1 growth cone in Drosophila
HY Fang, R Forghani, A Clarke, PG McQueen, A Chandrasekaran, ...
Molecular Biology of the Cell 34 (8), ar83, 2023
32023
A new view of axon growth and guidance grounded in the stochastic dynamics of actin networks
R Forghani, A Chandrasekaran, G Papoian, E Giniger
Open biology 13 (6), 220359, 2023
32023
Liquid-like assembly of VASP drives actin polymerization and bundling
KD Graham, A Chandrasekaran, L Wang, A Ladak, EM Lafer, ...
bioRxiv, 2022
22022
Kac’s ring: Entropy and Poincaré recurrence
A Chandrasekaran, SR Jain
Physica A: Statistical Mechanics and its Applications 391 (14), 3702-3707, 2012
22012
Liquid-like condensates that bind actin drive filament polymerization and bundling
C Walker, A Chandrasekaran, D Mansour, K Graham, A Torres, L Wang, ...
bioRxiv, 2024.05. 04.592527, 2024
2024
Kinetic trapping determines actin filament organization, thereby controlling the shape of liquid droplets
A Chandrasekaran, K Graham, L Wang, A Ladak, EM Lafer, ...
Biophysical Journal 123 (3), 492a, 2024
2024
Membrane curvature catalyzes actin nucleation through nano-scale condensation of N-WASP-FBP17
K Zhu, X Guo, A Chandrasekaran, X Miao, P Rangamani, W Zhao, Y Miao
bioRxiv, 2024.04. 25.591054, 2024
2024
Shells, rings, and networks—Determinants of actin configuration confined within VASP droplets
A Chandrasekaran, K Graham, L Wang, A Ladak, EM Lafer, ...
Biophysical Journal 122 (3), 262a, 2023
2023
Liquid-like assembly of VASP catalyzes actin polymerization and bundling
K Graham, A Chandrasekaran, L Wang, A Ladak, EM Lafer, P Rangamani, ...
Biophysical Journal 122 (3), 262a, 2023
2023
Computational modeling reveals that Abl signaling tunes actin networks between connected and fragmented states primarily through changes to the level of dendricity
A Chandrasekaran, A Clarke, P McQueen, HY Fang, GA Papoian, ...
Biophysical Journal 121 (3), 520a, 2022
2022
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