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Lara Marrone
Lara Marrone
Evotec
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RNA buffers the phase separation behavior of prion-like RNA binding proteins
S Maharana, J Wang, DK Papadopoulos, D Richter, A Pozniakovsky, ...
Science 360 (6391), 918-921, 2018
8912018
FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy
L Marrone, HCA Drexler, J Wang, P Tripathi, T Distler, P Heisterkamp, ...
Acta neuropathologica 138, 67-84, 2019
1032019
Isogenic FUS-eGFP iPSC reporter lines enable quantification of FUS stress granule pathology that is rescued by drugs inducing autophagy
L Marrone, I Poser, I Casci, J Japtok, P Reinhardt, A Janosch, C Andree, ...
Stem cell reports 10 (2), 375-389, 2018
972018
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease
RJ Wheeler, HO Lee, I Poser, A Pal, T Doeleman, S Kishigami, S Kour, ...
862019
Dual inhibition of GSK3β and CDK5 protects the cytoskeleton of neurons from neuroinflammatory-mediated degeneration in vitro and in vivo
L Reinhardt, S Kordes, P Reinhardt, M Glatza, M Baumann, HCA Drexler, ...
Stem cell reports 12 (3), 502-517, 2019
502019
Brain oxygen tension controls the expansion of outer subventricular zone-like basal progenitors in the developing mouse brain
L Wagenführ, AK Meyer, L Braunschweig, L Marrone, A Storch
Development 142 (17), 2904-2915, 2015
422015
Proteostatic imbalance and protein spreading in amyotrophic lateral sclerosis
ME Cicardi, L Marrone, M Azzouz, D Trotti
The EMBO journal 40 (10), e106389, 2021
362021
Oxygen tension within the neurogenic niche regulates dopaminergic neurogenesis in the developing midbrain
L Wagenführ, AK Meyer, L Marrone, A Storch
Stem Cells and Development 25 (3), 227-238, 2016
342016
Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization
I Casci, K Krishnamurthy, S Kour, V Tripathy, N Ramesh, EN Anderson, ...
Nature Communications 10 (1), 5583, 2019
322019
Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease
L Marrone, C Bus, D Schöndorf, JC Fitzgerald, M Kübler, B Schmid, ...
PloS one 13 (3), e0192497, 2018
292018
Circumventing the packaging limit of AAV-mediated gene replacement therapy for neurological disorders
L Marrone, PM Marchi, M Azzouz
Expert Opinion on Biological Therapy 22 (9), 1163-1176, 2022
252022
Primary Spinal OPC Culture System from Adult Zebrafish to Study Oligodendrocyte Differentiation In Vitro
V Kroehne, V Tsata, L Marrone, C Froeb, S Reinhardt, A Gompf, A Dahl, ...
Frontiers in Cellular Neuroscience 11, 284, 2017
182017
C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons
PM Marchi, L Marrone, L Brasseur, A Coens, CP Webster, L Bousset, ...
Life Science Alliance 5 (9), 2022
102022
Adoptive T-cell therapy in the treatment of viral and opportunistic fungal infections
N Mancini, L Marrone, N Clementi, GA Sautto, M Clementi, R Burioni
Future microbiology 10 (4), 665-682, 2015
102015
SPG15 protein deficits are at the crossroads between lysosomal abnormalities, altered lipid metabolism and synaptic dysfunction
L Marrone, PM Marchi, CP Webster, R Marroccella, I Coldicott, ...
Human Molecular Genetics 31 (16), 2693-2710, 2022
72022
SMN-deficient cells exhibit increased ribosomal DNA damage
E Karyka, NB Ramirez, CP Webster, PM Marchi, EJ Graves, VK Godena, ...
Life science alliance 5 (8), 2022
72022
P525L promotes the aggregation of FUS by altering its biochemical and biophysical properties
L Marrone, S Qamar, B Mannini, P St George-Hyslop, M Vendruscolo
Matters 6 (5), e202004000008, 2020
62020
Delivery of therapeutic AAV9 vectors via cisterna magna to treat neurological disorders
PM Marchi, L Marrone, M Azzouz
Trends in Molecular Medicine 28 (1), 79-80, 2022
52022
OS12. 1 Editing of IDH1 R132H mutation in human induced pluripotent stem cells to investigate tumor genesis in glioma
A Köpp, M Preussler, S Richter, M Heide, L Marrone, J Sterneckert, ...
Neuro-Oncology 21 (Suppl 3), iii22, 2019
32019
Phenotypic screening using mouse and human stem cell-based models of neuroinflammation and gene expression analysis to study drug responses
M Abo-Rady, J Bellmann, M Glatza, L Marrone, L Reinhardt, S Tena, ...
Systems Chemical Biology: Methods and Protocols, 21-43, 2019
32019
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Artículos 1–20