Mitochondrial dysfunction prevents repolarization of inflammatory macrophages J Van den Bossche, J Baardman, NA Otto, S van der Velden, AE Neele, ... Cell reports 17 (3), 684-696, 2016 | 702 | 2016 |
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages W Hoepel, HJ Chen, CE Geyer, S Allahverdiyeva, XD Manz, SW de Taeye, ... Science translational medicine 13 (596), eabf8654, 2021 | 172 | 2021 |
PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia SJ Bernelot Moens, AE Neele, J Kroon, FM Van Der Valk, ... European heart journal 38 (20), 1584-1593, 2017 | 171 | 2017 |
Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions MA Hoeksema, MJJ Gijbels, J Van den Bossche, S van der Velden, ... EMBO molecular medicine 6 (9), 1124-1132, 2014 | 165 | 2014 |
A defective pentose phosphate pathway reduces inflammatory macrophage responses during hypercholesterolemia J Baardman, SGS Verberk, KHM Prange, M van Weeghel, ... Cell reports 25 (8), 2044-2052. e5, 2018 | 161 | 2018 |
Macrophage polarization: the epigenetic point of view J Van den Bossche, AE Neele, MA Hoeksema, MPJ De Winther Current opinion in lipidology 25 (5), 367-373, 2014 | 101 | 2014 |
Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques J Baardman, SGS Verberk, S Van der Velden, MJJ Gijbels, ... Nature communications 11 (1), 6296, 2020 | 86 | 2020 |
Nanoparticle-aided characterization of arterial endothelial architecture during atherosclerosis progression and metabolic therapy TJ Beldman, TS Malinova, E Desclos, AE Grootemaat, ALS Misiak, ... ACS nano 13 (12), 13759-13774, 2019 | 84 | 2019 |
IFN-γ priming of macrophages represses a part of the inflammatory program and attenuates neutrophil recruitment MA Hoeksema, BP Scicluna, M Boshuizen, S Van Der Velden, AE Neele, ... The Journal of Immunology 194 (8), 3909-3916, 2015 | 80 | 2015 |
Epigenetic pathways in macrophages emerge as novel targets in atherosclerosis AE Neele, J Van den Bossche, MA Hoeksema, MPJ De Winther European journal of pharmacology 763, 79-89, 2015 | 77 | 2015 |
Inhibiting epigenetic enzymes to improve atherogenic macrophage functions J Van den Bossche, AE Neele, MA Hoeksema, F De Heij, MCS Boshuizen, ... Biochemical and biophysical research communications 455 (3-4), 396-402, 2014 | 74 | 2014 |
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses W Hoepel, HJ Chen, S Allahverdiyeva, X Manz, J Aman, ... BioRxiv, 2020.07. 13.190140, 2020 | 57 | 2020 |
Human monocyte-to-macrophage differentiation involves highly localized gain and loss of DNA methylation at transcription factor binding sites KF Dekkers, AE Neele, JW Jukema, BT Heijmans, MPJ de Winther Epigenetics & chromatin 12, 1-13, 2019 | 48 | 2019 |
Salt increases monocyte CCR2 expression and inflammatory responses in humans EFE Wenstedt, SGS Verberk, J Kroon, AE Neele, J Baardman, ... JCI insight 4 (21), 2019 | 43 | 2019 |
Interferon-β promotes macrophage foam cell formation by altering both cholesterol influx and efflux mechanisms MCS Boshuizen, MA Hoeksema, AE Neele, S van der Velden, ... Cytokine 77, 220-226, 2016 | 43 | 2016 |
High miR-124-3p expression identifies smoking individuals susceptible to atherosclerosis MWJ de Ronde, MGM Kok, PD Moerland, J Van den Bossche, AE Neele, ... Atherosclerosis 263, 377-384, 2017 | 41 | 2017 |
Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80+Clec4f+Vsig4+Ly6C− Kupffer Cell Subsets SJL van der Tuin, Z Li, JFP Berbée, I Verkouter, LE Ringnalda, AE Neele, ... Journal of the American Heart Association 7 (6), e008105, 2018 | 35 | 2018 |
Transglutaminase activity regulates atherosclerotic plaque composition at locations exposed to oscillatory shear stress HL Matlung, AE Neele, HC Groen, K van Gaalen, BG Tuna, A van Weert, ... Atherosclerosis 224 (2), 355-362, 2012 | 32 | 2012 |
Repressing the repressor: Ezh2 mediates macrophage activation AE Neele, MPJ de Winther Journal of Experimental Medicine 215 (5), 1269-1271, 2018 | 29 | 2018 |
Myeloid Kdm6b deficiency results in advanced atherosclerosis AE Neele, MJJ Gijbels, S van der Velden, MA Hoeksema, ... Atherosclerosis 275, 156-165, 2018 | 26 | 2018 |