Modeling of tumor growth and anticancer effects of combination therapy G Koch, A Walz, G Lahu, J Schropp Journal of pharmacokinetics and pharmacodynamics 36, 179-197, 2009 | 129 | 2009 |
Pharmacokinetics of fentanyl and its derivatives in children: a comprehensive review VC Ziesenitz, JD Vaughns, G Koch, G Mikus, JN van Den Anker Clinical pharmacokinetics 57 (2), 125-149, 2018 | 113 | 2018 |
Release and decay kinetics of copeptin vs AVP in response to osmotic alterations in healthy volunteers WK Fenske, I Schnyder, G Koch, C Walti, M Pfister, P Kopp, M Fassnacht, ... The Journal of Clinical Endocrinology & Metabolism 103 (2), 505-513, 2018 | 100 | 2018 |
Pharmacometrics and machine learning partner to advance clinical data analysis G Koch, M Pfister, I Daunhawer, M Wilbaux, S Wellmann, JE Vogt Clinical Pharmacology & Therapeutics 107 (4), 926-933, 2020 | 60 | 2020 |
Enhanced early prediction of clinically relevant neonatal hyperbilirubinemia with machine learning I Daunhawer, S Kasser, G Koch, L Sieber, H Cakal, J Tütsch, M Pfister, ... Pediatric research 86 (1), 122-127, 2019 | 55 | 2019 |
A study on discrete and discrete fractional pharmacokinetics-pharmacodynamics models for tumor growth and anti-cancer effects FM Atıcı, M Atıcı, N Nguyen, T Zhoroev, G Koch Computational and Mathematical Biophysics 7 (1), 10-24, 2019 | 52 | 2019 |
Modeling of delays in PKPD: classical approaches and a tutorial for delay differential equations G Koch, W Krzyzanski, JJ Pérez-Ruixo, J Schropp Journal of pharmacokinetics and pharmacodynamics 41, 291-318, 2014 | 48 | 2014 |
Caffeine citrate dosing adjustments to assure stable caffeine concentrations in preterm neonates G Koch, AN Datta, K Jost, SM Schulzke, J van den Anker, M Pfister The Journal of pediatrics 191, 50-56. e1, 2017 | 45 | 2017 |
Target‐mediated drug disposition model for bispecific antibodies: properties, approximation, and optimal dosing strategy J Schropp, A Khot, DK Shah, G Koch CPT: pharmacometrics & systems pharmacology 8 (3), 177-187, 2019 | 40 | 2019 |
Pharmacodynamic modeling of combined chemotherapeutic effects predicts synergistic activity of gemcitabine and trabectedin in pancreatic cancer cells X Miao, G Koch, RM Straubinger, WJ Jusko Cancer chemotherapy and pharmacology 77, 181-193, 2016 | 38 | 2016 |
Pharmacodynamic modeling of cell cycle effects for gemcitabine and trabectedin combinations in pancreatic cancer cells X Miao, G Koch, S Ait-Oudhia, RM Straubinger, WJ Jusko Frontiers in pharmacology 7, 421, 2016 | 36 | 2016 |
Assessment of non-linear combination effect terms for drug–drug interactions G Koch, J Schropp, WJ Jusko Journal of pharmacokinetics and pharmacodynamics 43, 461-479, 2016 | 32 | 2016 |
Clinical studies with 2-sulfanilamido-5-methoxypyrimidine P Bünger, G Koch Arzneimittel-forschung 11, 726-736, 1961 | 23 | 1961 |
Hydroxyethylstarch-related pruritus: a prospective multicentre investigation of 544 patients E Gröchenig, K Albegger, HJ Dieterich, RP Franke, E Gerlach, W Jurecka, ... PERFUSION-MUNICH THEN NURNBERG- 11, 62-78, 1998 | 22 | 1998 |
Optidose: computing the individualized optimal drug dosing regimen using optimal control F Bachmann, G Koch, M Pfister, G Szinnai, J Schropp Journal of Optimization Theory and Applications 189, 46-65, 2021 | 18 | 2021 |
Mathematical concepts in pharmacokinetics and pharmacodynamics with application to tumor growth G Koch, J Schropp Nonautonomous dynamical systems in the life sciences, 225-250, 2013 | 17 | 2013 |
Disease progression modeling to evaluate the effects of enzyme replacement therapy on kidney function in adult patients with the classic phenotype of Fabry disease A Nowak, G Koch, U Huynh-Do, M Siegenthaler, HP Marti, M Pfister Kidney and Blood Pressure Research 42 (1), 1-15, 2017 | 16 | 2017 |
Target-mediated drug disposition with drug–drug interaction, Part I: single drug case in alternative formulations G Koch, WJ Jusko, J Schropp Journal of pharmacokinetics and pharmacodynamics 44, 17-26, 2017 | 16 | 2017 |
Target mediated drug disposition with drug–drug interaction, Part II: competitive and uncompetitive cases G Koch, WJ Jusko, J Schropp Journal of pharmacokinetics and pharmacodynamics 44, 27-42, 2017 | 16 | 2017 |
Multi-response model for rheumatoid arthritis based on delay differential equations in collagen-induced arthritic mice treated with an anti-GM-CSF antibody G Koch, T Wagner, C Plater-Zyberk, G Lahu, J Schropp Journal of pharmacokinetics and pharmacodynamics 39, 55-65, 2012 | 16 | 2012 |