| Biologically inspired strategies for combating bacterial biofilms MS Blackledge, RJ Worthington, C Melander Current opinion in pharmacology 13 (5), 699-706, 2013 | 178 | 2013 |
| Small-molecule inhibition of bacterial two-component systems to combat antibiotic resistance and virulence RJ Worthington, MS Blackledge, C Melander Future medicinal chemistry 5 (11), 1265-1284, 2013 | 115 | 2013 |
| Targeting of Streptococcus mutans Biofilms by a Novel Small Molecule Prevents Dental Caries and Preserves the Oral Microbiome SS Garcia, MS Blackledge, S Michalek, L Su, T Ptacek, P Eipers, ... Journal of dental research 96 (7), 807-814, 2017 | 94 | 2017 |
| Programmable DNA-binding small molecules MS Blackledge, C Melander Bioorganic & medicinal chemistry 21 (20), 6101-6114, 2013 | 80 | 2013 |
| The Discovery of 2‐Aminobenzimidazoles That Sensitize Mycobacterium smegmatis and M. tuberculosis to β‐Lactam Antibiotics in a Pattern Distinct from β … TV Nguyen, MS Blackledge, EA Lindsey, BM Minrovic, DF Ackart, ... Angewandte Chemie 129 (14), 3998-4002, 2017 | 36 | 2017 |
| From antihistamine to anti-infective: loratadine inhibition of regulatory PASTA kinases in Staphylococci reduces biofilm formation and potentiates β-lactam antibiotics and … N Cutrona, K Gillard, R Ulrich, M Seemann, HB Miller, MS Blackledge ACS infectious diseases 5 (8), 1397-1410, 2019 | 29 | 2019 |
| 2-aminoimidazoles potentiate ß-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing ß-lactamase secretion and increasing cell envelope … AB Jeon, A Obregon-Henao, DF Ackart, BK Podell, JM Belardinelli, ... PloS one 12 (7), e0180925, 2017 | 22 | 2017 |
| Tricyclic amine antidepressants suppress β‐lactam resistance in methicillin‐resistant Staphylococcus aureus (MRSA) by repressing mRNA levels of key resistance … K Gillard, HB Miller, MS Blackledge Chemical Biology & Drug Design 92 (5), 1822-1829, 2018 | 19 | 2018 |
| Electrochemical detection of small molecule induced Pseudomonas aeruginosa biofilm dispersion AJ Robb, S Vinogradov, AS Danell, E Anderson, MS Blackledge, ... Electrochimica acta 268, 276-282, 2018 | 18 | 2018 |
| Membrane-permeabilizing activity of reverse-amide 2-aminoimidazole antibiofilm agents against Acinetobacter baumannii S D Stowe, R J Thompson, L Peng, Z Su, M S Blackledge, ... Current drug delivery 12 (2), 223-230, 2015 | 17 | 2015 |
| Resensitization of methicillin-resistant Staphylococcus aureus by amoxapine, an FDA-approved antidepressant TJ Wilson, MS Blackledge, PA Vigueira Heliyon 4 (1), 2018 | 16 | 2018 |
| Evaluation of small molecule kinase inhibitors as novel antimicrobial and antibiofilm agents A King, MS Blackledge Chemical biology & drug design 98 (6), 1038-1064, 2021 | 13 | 2021 |
| Small-molecule inhibition of bacterial two-component systems to combat antibiotic resistance and virulence. Future Med Chem 5: 1265–1284 RJ Worthington, MS Blackledge, C Melander | 12 | 2013 |
| Functionalized self-assembled monolayers: versatile strategies to combat bacterial biofilm formation PM Lundin, BL Fiser, MS Blackledge, HL Pickett, AL Copeland Pharmaceutics 14 (8), 1613, 2022 | 10 | 2022 |
| Identification and evaluation of brominated carbazoles as a novel antibiotic adjuvant scaffold in MRSA R Berndsen, T Cunningham, L Kaelin, M Callender, WD Boldog, B Viering, ... ACS Medicinal Chemistry Letters 13 (3), 483-491, 2022 | 10 | 2022 |
| Brominated carbazole with antibiotic adjuvant activity displays pleiotropic effects in MRSA’s transcriptome B Viering, T Cunningham, A King, MS Blackledge, HB Miller ACS chemical biology 17 (5), 1239-1248, 2022 | 2 | 2022 |
| Small-molecule adjuvants for antibiotics to address antibiotic resistance MS Blackledge, PA Vigueira, HB Miller US Patent App. 16/158,928, 2019 | 2 | 2019 |
| Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator C Liu, H Zhang, X Peng, MS Blackledge, RE Furlani, H Li, Z Su, ... Mbio 14 (3), e00137-23, 2023 | 1 | 2023 |
| Loratadine Combats Methicillin-Resistant Staphylococcus aureus by Modulating Virulence, Antibiotic Resistance, and Biofilm Genes BL Viering, H Balogh, CF Cox, OK Kirpekar, AL Akers, VA Federico, ... ACS Infectious Diseases 10 (1), 232-250, 2023 | | 2023 |
| Transcriptomic Analysis of Loratadine as an Antibiotic Adjuvant Against MRSA B Viering, H Balogh, L Akers, M Blackledge, H Miller | | 2023 |
Christian MelanderUniversity of Notre DameDirección de correo verificada de nd.edu
