The catalytic enantioselective construction of molecules with quaternary carbon stereocenters EJ Corey, A Guzman‐Perez Angewandte Chemie International Edition 37 (4), 388-401, 1998 | 1405 | 1998 |
Correction to Analyzing Learned Molecular Representations for Property Prediction. K Yang, K Swanson, W Jin, C Coley, P Eiden, H Gao, A Guzman-Perez, ... Journal of chemical information and modeling 59 (12), 5304, 2019 | 1395* | 2019 |
Analyzing learned molecular representations for property prediction K Yang, K Swanson, W Jin, C Coley, P Eiden, H Gao, A Guzman-Perez, ... Journal of chemical information and modeling 59 (8), 3370-3388, 2019 | 1395 | 2019 |
Der katalytische enantioselektive Aufbau von Molekülen mit quartären Kohlenstoff‐Stereozentren EJ Corey, A Guzman‐Perez Angewandte Chemie 110 (4), 402-415, 1998 | 297 | 1998 |
The application of a mechanistic model leads to the extension of the Sharpless asymmetric dihydroxylation to allylic 4-methoxybenzoates and conformationally related amine and … EJ Corey, A Guzman-Perez, MC Noe Journal of the American Chemical Society 117 (44), 10805-10816, 1995 | 196 | 1995 |
Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis L Buckbinder, DT Crawford, H Qi, HZ Ke, LM Olson, KR Long, ... Proceedings of the National Academy of Sciences 104 (25), 10619-10624, 2007 | 179 | 2007 |
Demonstration of the synthetic power of oxazaborolidine-catalyzed enantioselective Diels-Alder reactions by very efficient routes to cassiol and gibberellic acid EJ Corey, A Guzman-Perez, TP Loh Journal of the American Chemical Society 116 (8), 3611-3612, 1994 | 134 | 1994 |
Discovery of (S)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical … JA Pfefferkorn, A Guzman-Perez, J Litchfield, R Aiello, JL Treadway, ... Journal of medicinal chemistry 55 (3), 1318-1333, 2012 | 132 | 2012 |
Short enantioselective synthesis of (-)-ovalicin, a potent inhibitor of angiogenesis, using substrate-enhanced catalytic asymmetric dihydroxylation EJ Corey, A Guzman-Perez, MC Noe Journal of the American Chemical Society 116 (26), 12109-12110, 1994 | 128 | 1994 |
A novel sodium-hydrogen exchanger isoform-1 inhibitor, zoniporide, reduces ischemic myocardial injury in vitro and in vivo DR Knight, AH Smith, DM Flynn, JT MacAndrew, SS Ellery, JX Kong, ... Journal of Pharmacology and Experimental Therapeutics 297 (1), 254-259, 2001 | 104 | 2001 |
Discovery of PF-04620110, a potent, selective, and orally bioavailable inhibitor of DGAT-1 RL Dow, JC Li, MP Pence, EM Gibbs, JL LaPerle, J Litchfield, ... ACS medicinal chemistry letters 2 (5), 407-412, 2011 | 100 | 2011 |
Discovery of zoniporide: A potent and selective sodium–hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility A Guzman-Perez, RT Wester, MC Allen, JA Brown, AR Buchholz, ... Bioorganic & medicinal chemistry letters 11 (6), 803-807, 2001 | 97 | 2001 |
Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors H Bregman, N Chakka, A Guzman-Perez, H Gunaydin, Y Gu, X Huang, ... Journal of medicinal chemistry 56 (11), 4320-4342, 2013 | 89 | 2013 |
Pyridones as glucokinase activators: identification of a unique metabolic liability of the 4-sulfonyl-2-pyridone heterocycle JA Pfefferkorn, J Lou, ML Minich, KJ Filipski, M He, R Zhou, S Ahmed, ... Bioorganic & medicinal chemistry letters 19 (12), 3247-3252, 2009 | 85 | 2009 |
Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity DP Walker, MP Zawistoski, MA McGlynn, JC Li, DW Kung, PC Bonnette, ... Bioorganic & medicinal chemistry letters 19 (12), 3253-3258, 2009 | 85 | 2009 |
Kinetic resolution by enantioselective dihydroxylation of secondary allylic 4-methoxybenzoate esters using a mechanistically designed cinchona alkaloid catalyst EJ Corey, MC Noe, A Guzman-Perez Journal of the American Chemical Society 117 (44), 10817-10824, 1995 | 84 | 1995 |
An Enantioselective Synthetic Route to Atractyligenin Using the Oxazaborolidine-Catalyzed Reduction of β-Silyl-or β-Stannyl-Substituted α, β-Enones as a Key Step EJ Corey, A Guzman-Perez, SE Lazerwith Journal of the American Chemical Society 119 (49), 11769-11776, 1997 | 79 | 1997 |
Designing glucokinase activators with reduced hypoglycemia risk: discovery of N, N-dimethyl-5-(2-methyl-6-((5-methylpyrazin-2-yl)-carbamoyl) benzofuran-4-yloxy) pyrimidine-2 … JA Pfefferkorn, A Guzman-Perez, PJ Oates, J Litchfield, G Aspnes, ... MedChemComm 2 (9), 828-839, 2011 | 76 | 2011 |
Functionalization of Aromatic Amino Acids via Direct C− H Activation: Generation of Versatile Building Blocks for Accessing Novel Peptide Space FM Meyer, S Liras, A Guzman-Perez, C Perreault, J Bian, K James Organic Letters 12 (17), 3870-3873, 2010 | 72 | 2010 |
Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that … RF Graceffa, AA Boezio, J Able, S Altmann, LM Berry, C Boezio, JR Butler, ... Journal of medicinal chemistry 60 (14), 5990-6017, 2017 | 67 | 2017 |