Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs LP Lim, NC Lau, P Garrett-Engele, A Grimson, JM Schelter, J Castle, ... Nature 433 (7027), 769-773, 2005 | 6058 | 2005 |
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans NC Lau, LP Lim, EG Weinstein, DP Bartel Science 294 (5543), 858-862, 2001 | 4847 | 2001 |
The microRNAs of Caenorhabditis elegans LP Lim, NC Lau, EG Weinstein, A Abdelhakim, S Yekta, MW Rhoades, ... Genes & development 17 (8), 991-1008, 2003 | 1858 | 2003 |
Characterization of the piRNA complex from rat testes NC Lau, AG Seto, J Kim, S Kuramochi-Miyagawa, T Nakano, DP Bartel, ... Science 313 (5785), 363-367, 2006 | 1142 | 2006 |
The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans AL Abbott, E Alvarez-Saavedra, EA Miska, NC Lau, DP Bartel, HR Horvitz, ... Developmental cell 9 (3), 403-414, 2005 | 629 | 2005 |
Most Caenorhabditis elegans microRNAs are individually not essential for development or viability EA Miska, E Alvarez-Saavedra, AL Abbott, NC Lau, AB Hellman, ... PLoS genetics 3 (12), e215, 2007 | 593 | 2007 |
Virus discovery by deep sequencing and assembly of virus-derived small silencing RNAs Q Wu, Y Luo, R Lu, N Lau, EC Lai, WX Li, SW Ding Proceedings of the National Academy of Sciences 107 (4), 1606-1611, 2010 | 540 | 2010 |
The coming of age for Piwi proteins AG Seto, RE Kingston, NC Lau Molecular cell 26 (5), 603-609, 2007 | 372 | 2007 |
A broadly conserved pathway generates 3′ UTR-directed primary piRNAs N Robine, NC Lau, S Balla, Z Jin, K Okamura, S Kuramochi-Miyagawa, ... Current Biology 19 (24), 2066-2076, 2009 | 369 | 2009 |
Abundant primary piRNAs, endo-siRNAs, and microRNAs in a Drosophila ovary cell line NC Lau, N Robine, R Martin, WJ Chung, Y Niki, E Berezikov, EC Lai Genome research 19 (10), 1776-1785, 2009 | 222 | 2009 |
Quantitative genome-wide enhancer activity maps for five Drosophila species show functional enhancer conservation and turnover during cis-regulatory evolution CD Arnold, D Gerlach, D Spies, JA Matts, YA Sytnikova, M Pagani, ... Nature genetics 46 (7), 685-692, 2014 | 195 | 2014 |
Regulatory mutations of mir-48, a C. elegans let-7 family MicroRNA, cause developmental timing defects M Li, MW Jones-Rhoades, NC Lau, DP Bartel, AE Rougvie Developmental cell 9 (3), 415-422, 2005 | 120 | 2005 |
Unique transposon landscapes are pervasive across Drosophila melanogaster genomes R Rahman, G Chirn, A Kanodia, YA Sytnikova, B Brembs, CM Bergman, ... Nucleic acids research 43 (22), 10655-10672, 2015 | 118 | 2015 |
Systematic and single cell analysis of Xenopus Piwi‐interacting RNAs and Xiwi NC Lau, T Ohsumi, M Borowsky, RE Kingston, MD Blower The EMBO journal 28 (19), 2945-2958, 2009 | 98 | 2009 |
The capacity of target silencing by Drosophila PIWI and piRNAs C Post, JP Clark, YA Sytnikova, GW Chirn, NC Lau Rna 20 (12), 1977-1986, 2014 | 96 | 2014 |
Conserved piRNA expression from a distinct set of piRNA cluster loci in eutherian mammals G Chirn, R Rahman, YA Sytnikova, JA Matts, M Zeng, D Gerlach, M Yu, ... PLoS genetics 11 (11), e1005652, 2015 | 89 | 2015 |
Transposable element dynamics and PIWI regulation impacts lncRNA and gene expression diversity in Drosophila ovarian cell cultures YA Sytnikova, R Rahman, G Chirn, JP Clark, NC Lau Genome research 24 (12), 1977-1990, 2014 | 59 | 2014 |
Two self-splicing group I introns in the ribonucleotide reductase large subunit gene of Staphylococcus aureus phage Twort M Landthaler, U Begley, NC Lau, DA Shub Nucleic acids research 30 (9), 1935-1943, 2002 | 59 | 2002 |
RNAi pathways contribute to developmental history-dependent phenotypic plasticity in C. elegans SE Hall, GW Chirn, NC Lau, P Sengupta Rna 19 (3), 306-319, 2013 | 56 | 2013 |
Rem2 is an activity-dependent negative regulator of dendritic complexity in vivo AE Ghiretti, AR Moore, RG Brenner, LF Chen, AE West, NC Lau, ... Journal of Neuroscience 34 (2), 392-407, 2014 | 53 | 2014 |