Alexandra Rucavado
Alexandra Rucavado
Universidad de Costa Rica, Instituto Clodomiro Picado
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Snake venom metalloproteinases: their role in the pathogenesis of local tissue damage
JM Gutiérrez, A Rucavado
Biochimie 82 (9-10), 841-850, 2000
Hemorrhage induced by snake venom metalloproteinases: biochemical and biophysical mechanisms involved in microvessel damage
JM Gutiérrez, A Rucavado, T Escalante, C Díaz
Toxicon 45 (8), 997-1011, 2005
Brucella abortus Uses a Stealthy Strategy to Avoid Activation of the Innate Immune System during the Onset of Infection
E Barquero-Calvo, E Chaves-Olarte, DS Weiss, C Guzman-Verri, ...
PloS one 2 (7), e631, 2007
Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases
T Escalante, A Rucavado, JW Fox, JM Gutiérrez
Journal of proteomics 74 (9), 1781-1794, 2011
Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom
JM Gutiérrez, G León, G Rojas, B Lomonte, A Rucavado, F Chaves
Toxicon 36 (11), 1529-1538, 1998
Experimental pathology of local tissue damage induced by Bothrops asper snake venom
JM Gutiérrez, A Rucavado, F Chaves, C Díaz, T Escalante
Toxicon 54 (7), 958-975, 2009
Trends in snakebite envenomation therapy: scientific, technological and public health considerations
JM Gutierrez, B Lomonte, G León, A Rucavado, F Chaves, Y Angulo
Current pharmaceutical design 13 (28), 2935-2950, 2007
Neutralization of proteases from Bothrops snake venoms by the aqueous extract from Casearia sylvestris (Flacourtiaceae)
MH Borges, AM Soares, VM Rodrigues, F Oliveira, AM Fransheschi, ...
Toxicon 39 (12), 1863-1869, 2001
Experimental pathophysiology of systemic alterations induced by Bothrops asper snake venom
JM Gutiérrez, T Escalante, A Rucavado
Toxicon 54 (7), 976-987, 2009
Hemorrhage caused by snake venom metalloproteinases: a journey of discovery and understanding
JM Gutiérrez, T Escalante, A Rucavado, C Herrera
Toxins 8 (4), 93, 2016
Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue‐damaging activities
L Watanabe, JD Shannon, RH Valente, A Rucavado, A Alape‐Girón, ...
Protein science 12 (10), 2273-2281, 2003
Inhibition of local hemorrhage and dermonecrosis induced by Bothrops asper snake venom: effectiveness of early in situ administration of the peptidomimetic metalloproteinase …
A Rucavado, T Escalante, A Franceschi, F Chaves, Y Cury, M Ovadia
The American journal of tropical medicine and hygiene 63 (5), 313-319, 2000
Local tissue damage induced by BaP1, a metalloproteinase isolated from Bothrops asper (Terciopelo) snake venom
A Rucavado, B Lomonte, M Ovadia, JM Gutiérrez
Experimental and molecular pathology 63 (3), 186-199, 1995
Blister formation and skin damage induced by BaP1, a haemorrhagic metalloproteinase from the venom of the snake Bothrops asper.
A Rucavado, J Núñez, JM Gutiérrez
International journal of experimental pathology 79 (4), 245, 1998
Increments in cytokines and matrix metalloproteinases in skeletal muscle after injection of tissue-damaging toxins from the venom of the snake Bothrops asper
A Rucavado, T Escalante, CFP Teixeira, CM Fernándes, C Díaz, ...
Mediators of Inflammation 11 (2), 121-128, 2002
Snake Venomics of the Lesser Antillean Pit Vipers Bothrops caribbaeus and Bothrops lanceolatus: Correlation with Toxicological Activities and Immunoreactivity of …
JM Gutiérrez, L Sanz, J Escolano, J Fernandez, B Lomonte, Y Angulo, ...
Journal of proteome research 7 (10), 4396-4408, 2008
Effectiveness of batimastat, a synthetic inhibitor of matrix metalloproteinases, in neutralizing local tissue damage induced by BaP1, a hemorrhagic metalloproteinase from the …
T Escalante, A Franceschi, A Rucavado, JM Gutiérrez
Biochemical pharmacology 60 (2), 269-274, 2000
Snake venom metalloproteinases. Biological roles and participation in the pathophysiology of envenomation.
T Escalante, A Rucavado, JM Gutiérrez
Handbook of venoms and toxins of reptiles, 115-138, 2009
Purification and characterization of BaH4, a hemorrhagic metalloproteinase from the venom of the snake Bothrops asper
A Franceschi, A Rucavado, N Mora, JM Gutiérrez
Toxicon 38 (1), 63-77, 2000
Inflammatory effects of BaP1 a metalloproteinase isolated from Bothrops asper snake venom: leukocyte recruitment and release of cytokines
CM Fernandes, SR Zamuner, JP Zuliani, A Rucavado, JM Gutiérrez, ...
Toxicon 47 (5), 549-559, 2006
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