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Michael Torrens-Spence
Michael Torrens-Spence
Postdoctoral Researcher Whitehead Institute MIT
Dirección de correo verificada de wi.mit.edu
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PBS3 and EPS1 complete salicylic acid biosynthesis from isochorismate in Arabidopsis
MP Torrens-Spence, A Bobokalonova, V Carballo, CM Glinkerman, ...
Molecular plant 12 (12), 1577-1586, 2019
2302019
Complete pathway elucidation and heterologous reconstitution of Rhodiola salidroside biosynthesis
MP Torrens-Spence, T Pluskal, FS Li, V Carballo, JK Weng
Molecular plant 11 (1), 205-217, 2018
1192018
The biosynthetic origin of psychoactive kavalactones in kava
T Pluskal, MP Torrens-Spence, TR Fallon, A De Abreu, CH Shi, JK Weng
Nature plants 5 (8), 867-878, 2019
712019
Biochemical evaluation of the decarboxylation and decarboxylation-deamination activities of plant aromatic amino acid decarboxylases
MP Torrens-Spence, P Liu, H Ding, K Harich, G Gillaspy, J Li
Journal of Biological Chemistry 288 (4), 2376-2387, 2013
702013
Investigation of a substrate-specifying residue within Papaver somniferum and Catharanthus roseus aromatic amino acid decarboxylases
MP Torrens-Spence, M Lazear, R von Guggenberg, H Ding, J Li
Phytochemistry 106, 37-43, 2014
472014
Structural basis for divergent and convergent evolution of catalytic machineries in plant aromatic amino acid decarboxylase proteins
MP Torrens-Spence, YC Chiang, T Smith, MA Vicent, Y Wang, JK Weng
Proceedings of the National Academy of Sciences 117 (20), 10806-10817, 2020
422020
Biochemical evaluation of a parsley tyrosine decarboxylase results in a novel 4-hydroxyphenylacetaldehyde synthase enzyme
MP Torrens-Spence, G Gillaspy, B Zhao, K Harich, RH White, J Li
Biochemical and biophysical research communications 418 (2), 211-216, 2012
312012
Monoamine biosynthesis via a noncanonical calcium-activatable aromatic amino acid decarboxylase in psilocybin mushroom
MP Torrens-Spence, CT Liu, T Pluskal, YK Chung, JK Weng
ACS chemical biology 13 (12), 3343-3353, 2018
232018
A workflow for studying specialized metabolism in nonmodel eukaryotic organisms
MP Torrens-Spence, TR Fallon, JK Weng
Methods in enzymology 576, 69-97, 2016
222016
Mechanism of cysteine-dependent inactivation of aspartate/glutamate/cysteine sulfinic acid α-decarboxylases
P Liu, MP Torrens-Spence, H Ding, BM Christensen, J Li
Amino Acids 44, 391-404, 2013
222013
Production of nonnatural straight-chain amino acid 6-aminocaproate via an artificial iterative carbon-chain-extension cycle
J Cheng, G Hu, Y Xu, MP Torrens-Spence, X Zhou, D Wang, JK Weng, ...
Metabolic engineering 55, 23-32, 2019
192019
Diverse functional evolution of serine decarboxylases: identification of two novel acetaldehyde synthases that uses hydrophobic amino acids as substrates
MP Torrens-Spence, R von Guggenberg, M Lazear, H Ding, J Li
BMC plant biology 14, 1-10, 2014
192014
Imine chemistry in plant metabolism
MP Torrens-Spence, CM Glinkerman, J Günther, JK Weng
Current opinion in plant biology 60, 101999, 2021
82021
Structural basis for independent origins of new catalytic machineries in plant AAAD proteins
MP Torrens-Spence, YC Chiang, T Smith, MA Vicent, Y Wang, JK Weng
BioRxiv, 404970, 2018
82018
Engineering new branches of the kynurenine pathway to produce oxo-(2-aminophenyl) and quinoline scaffolds in yeast
MP Torrens-Spence, CT Liu, JK Weng
ACS Synthetic Biology 8 (12), 2735-2745, 2019
72019
Compositions and Methods for Production of Salidroside, Icariside D2, and Precursors of Salidroside and Icariside D2
M Torrens-Spence, W Jing-Ke
US Patent App. 17/847,313, 2023
22023
Mechanistic basis for the emergence of EPS1 as a catalyst in plant salicylic acid biosynthesis
MP Torrens-Spence, T Li, Z Wang, CM Glinkerman, JO Matos, Y Wang, ...
bioRxiv, 2021.08. 21.457228, 2021
22021
Structural analysis for a 1-piperidine-2-carboxylic acid reductase reveals functional conservation of a pipecolic acid pathway in systemic acquired resistance
P Ding, M Torrens-Spence, JDG Jones, JK Weng
2019 IS-MPMI XVIII Congress, 2019
2019
Production of nonnatural straight-chain amino acid 6-aminocaproate via an artificial iterative carbon-chain-extension cycle
MP Torrens-Spence, JK Weng
Elsevier BV, 2019
2019
Diverse functional evolution of type II pyridoxal 5'-phosphate decarboxylases: Detection of two novel acetaldehyde synthases that uses hydrophobic amino acids as substrates.
M Torrens-Spence, R Guggenberg, M Lazear, H Ding, J Li
BMC Plant Biology 14 (1), 2014
2014
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