| An improved procedure for the preparation of the Dess-Martin periodinane RE Ireland, L Liu The Journal of Organic Chemistry 58 (10), 2899-2899, 1993 | 1054 | 1993 |
| Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors BA Lanman, JR Allen, JG Allen, AK Amegadzie, KS Ashton, SK Booker, ... Journal of medicinal chemistry 63 (1), 52-65, 2019 | 506 | 2019 |
| Improved methodology for photocyclization reactions L Liu, B Yang, TJ Katz, MK Poindexter The Journal of Organic Chemistry 56 (12), 3769-3775, 1991 | 405 | 1991 |
| A soluble base for the copper-catalyzed imidazole N-arylations with aryl halides L Liu, M Frohn, N Xi, C Dominguez, R Hungate, PJ Reider The Journal of Organic Chemistry 70 (24), 10135-10138, 2005 | 207 | 2005 |
| Structure−Activity Relationships of a Series of Pyrrolo[3,2-d]pyrimidine Derivatives and Related Compounds as Neuropeptide Y5 Receptor Antagonists MH Norman, N Chen, Z Chen, C Fotsch, C Hale, N Han, R Hurt, T Jenkins, ... Journal of medicinal chemistry 43 (22), 4288-4312, 2000 | 178 | 2000 |
| Fused heterocyclic derivatives and methods of use BK Albrecht, D Bauer, A Boezio, D Choquette, JC Harmange, RT Lewis, ... US Patent 8,198,448, 2012 | 158 | 2012 |
| Drug repurposing: the anthelmintics niclosamide and nitazoxanide are potent TMEM16A antagonists that fully bronchodilate airways K Miner, K Labitzke, B Liu, P Wang, K Henckels, K Gaida, R Elliott, ... Frontiers in pharmacology 10, 51, 2019 | 131 | 2019 |
| Fused heterocyclic derivatives and methods of use BK Albrecht, D Bauer, S Bellon, CM Bode, A Boezio, D Choquette, ... US Patent 8,212,041, 2012 | 128 | 2012 |
| Discovery and optimization of a series of benzothiazole phosphoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors ND D’Angelo, TS Kim, K Andrews, SK Booker, S Caenepeel, K Chen, ... Journal of medicinal chemistry 54 (6), 1789-1811, 2011 | 127 | 2011 |
| An efficient synthesis of functionalized helicenes TJ Katz, L Liu, ND Willmore, JM Fox, AL Rheingold, S Shi, C Nuckolls, ... Journal of the American Chemical Society 119 (42), 10054-10063, 1997 | 127 | 1997 |
| Simple preparation of a helical quinone L Liu, TJ Katz Tetrahedron letters 31 (28), 3983-3986, 1990 | 120 | 1990 |
| Discovery of a Potent, Selective, and Orally Bioavailable c-Met Inhibitor: 1-(2-Hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl … L Liu, A Siegmund, N Xi, P Kaplan-Lefko, K Rex, A Chen, J Lin, ... Journal of medicinal chemistry 51 (13), 3688-3691, 2008 | 119 | 2008 |
| Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors DJ Lloyd, DJ St Jean Jr, RJM Kurzeja, RC Wahl, K Michelsen, R Cupples, ... Nature 504 (7480), 437-440, 2013 | 106 | 2013 |
| Structure-based design of novel class II c-Met inhibitors: 1. Identification of pyrazolone-based derivatives MH Norman, L Liu, M Lee, N Xi, I Fellows, ND D’Angelo, C Dominguez, ... Journal of Medicinal Chemistry 55 (5), 1858-1867, 2012 | 104 | 2012 |
| Design, synthesis, and biological evaluation of potent c-Met inhibitors ND D’Angelo, SF Bellon, SK Booker, Y Cheng, A Coxon, C Dominguez, ... Journal of medicinal chemistry 51 (18), 5766-5779, 2008 | 97 | 2008 |
| Fused heterocyclic derivatives and methods of use BK Albrecht, D Bauer, S Bellon, CM Bode, A Boezio, D Choquette, ... US Patent 8,217,177, 2012 | 91 | 2012 |
| A Diels–Alder Route to [5]‐and [6]‐Helicenes ND Willmore, L Liu, TJ Katz Angewandte Chemie International Edition in English 31 (8), 1093-1095, 1992 | 90 | 1992 |
| Substituted heterocycles and methods of use TS Kim, S Bellon, S Booker, N D'angelo, C Dominguez, I Fellows, M Lee, ... US Patent 7,652,009, 2010 | 88 | 2010 |
| Compounds and methods which modulate feeding behavior and related diseases MH Norman, CR Hurt, N Chen, CH Fotsch, N Han, TJ Jenkins, L Liu, ... US Patent 6,187,777, 2001 | 81 | 2001 |
| Imidazopyridazine inhibitors of PI3 kinase for cancer treatment S Booker, TS Kim, H Liao, L Liu, MH Norman, EA Peterson, M Stec, ... US Patent 7,820,665, 2010 | 78 | 2010 |
