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Longbin Liu
Longbin Liu
CHDI Foundation
Dirección de correo verificada de chdifoundation.org
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An improved procedure for the preparation of the Dess-Martin periodinane
RE Ireland, L Liu
The Journal of Organic Chemistry 58 (10), 2899-2899, 1993
9791993
Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors
BA Lanman, JR Allen, JG Allen, AK Amegadzie, KS Ashton, SK Booker, ...
Journal of medicinal chemistry 63 (1), 52-65, 2019
4882019
Improved methodology for photocyclization reactions
L Liu, B Yang, TJ Katz, MK Poindexter
The Journal of Organic Chemistry 56 (12), 3769-3775, 1991
4071991
A soluble base for the copper-catalyzed imidazole N-arylations with aryl halides
L Liu, M Frohn, N Xi, C Dominguez, R Hungate, PJ Reider
The Journal of Organic Chemistry 70 (24), 10135-10138, 2005
2072005
Structure−Activity Relationships of a Series of Pyrrolo[3,2-d]pyrimidine Derivatives and Related Compounds as Neuropeptide Y5 Receptor Antagonists
MH Norman, N Chen, Z Chen, C Fotsch, C Hale, N Han, R Hurt, T Jenkins, ...
Journal of medicinal chemistry 43 (22), 4288-4312, 2000
1732000
Fused heterocyclic derivatives and methods of use
BK Albrecht, D Bauer, A Boezio, D Choquette, JC Harmange, RT Lewis, ...
US Patent 8,198,448, 2012
1572012
Drug repurposing: the anthelmintics niclosamide and nitazoxanide are potent TMEM16A antagonists that fully bronchodilate airways
K Miner, K Labitzke, B Liu, P Wang, K Henckels, K Gaida, R Elliott, ...
Frontiers in pharmacology 10, 51, 2019
1302019
An efficient synthesis of functionalized helicenes
TJ Katz, L Liu, ND Willmore, JM Fox, AL Rheingold, S Shi, C Nuckolls, ...
Journal of the American Chemical Society 119 (42), 10054-10063, 1997
1301997
Fused heterocyclic derivatives and methods of use
BK Albrecht, D Bauer, S Bellon, CM Bode, A Boezio, D Choquette, ...
US Patent 8,212,041, 2012
1272012
Discovery and optimization of a series of benzothiazole phosphoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors
ND D’Angelo, TS Kim, K Andrews, SK Booker, S Caenepeel, K Chen, ...
Journal of medicinal chemistry 54 (6), 1789-1811, 2011
1252011
Simple preparation of a helical quinone
L Liu, TJ Katz
Tetrahedron letters 31 (28), 3983-3986, 1990
1221990
Discovery of a Potent, Selective, and Orally Bioavailable c-Met Inhibitor: 1-(2-Hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl …
L Liu, A Siegmund, N Xi, P Kaplan-Lefko, K Rex, A Chen, J Lin, ...
Journal of medicinal chemistry 51 (13), 3688-3691, 2008
1172008
Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors
DJ Lloyd, DJ St Jean Jr, RJM Kurzeja, RC Wahl, K Michelsen, R Cupples, ...
Nature 504 (7480), 437-440, 2013
1062013
Structure-based design of novel class II c-Met inhibitors: 1. Identification of pyrazolone-based derivatives
MH Norman, L Liu, M Lee, N Xi, I Fellows, ND D’Angelo, C Dominguez, ...
Journal of Medicinal Chemistry 55 (5), 1858-1867, 2012
1042012
Design, synthesis, and biological evaluation of potent c-Met inhibitors
ND D’Angelo, SF Bellon, SK Booker, Y Cheng, A Coxon, C Dominguez, ...
Journal of medicinal chemistry 51 (18), 5766-5779, 2008
972008
Fused heterocyclic derivatives and methods of use
BK Albrecht, D Bauer, S Bellon, CM Bode, A Boezio, D Choquette, ...
US Patent 8,217,177, 2012
902012
A Diels–Alder Route to [5]‐and [6]‐Helicenes
ND Willmore, L Liu, TJ Katz
Angewandte Chemie International Edition in English 31 (8), 1093-1095, 1992
891992
Substituted heterocycles and methods of use
TS Kim, S Bellon, S Booker, N D'angelo, C Dominguez, I Fellows, M Lee, ...
US Patent 7,652,009, 2010
872010
Compounds and methods which modulate feeding behavior and related diseases
MH Norman, CR Hurt, N Chen, CH Fotsch, N Han, TJ Jenkins, L Liu, ...
US Patent 6,187,777, 2001
802001
Structure-based design of novel class II c-Met inhibitors: 2. SAR and kinase selectivity profiles of the pyrazolone series
L Liu, MH Norman, M Lee, N Xi, A Siegmund, AA Boezio, S Booker, ...
Journal of Medicinal Chemistry 55 (5), 1868-1897, 2012
772012
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