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Gayan Mirihana Arachchilage, PhD
Gayan Mirihana Arachchilage, PhD
PTC Therapeutics
Dirección de correo verificada de ptcbio.com
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Metal cations in G-quadruplex folding and stability
D Bhattacharyya, G Mirihana Arachchilage, S Basu
Frontiers in chemistry 4, 38, 2016
5702016
A potassium ion-dependent RNA structural switch regulates human pre-miRNA 92b maturation
GM Arachchilage, AC Dassanayake, S Basu
Chemistry & biology 22 (2), 262-272, 2015
1292015
Genome-wide discovery of structured noncoding RNAs in bacteria
S Stav, RM Atilho, G Mirihana Arachchilage, G Nguyen, G Higgs, ...
BMC microbiology 19, 1-18, 2019
472019
SAM-VI RNAs selectively bind S-adenosylmethionine and exhibit similarities to SAM-III riboswitches
G Mirihana Arachchilage, ME Sherlock, Z Weinberg, RR Breaker
RNA biology 15 (3), 371-378, 2018
472018
Challenges of ligand identification for the second wave of orphan riboswitch candidates
EB Greenlee, S Stav, RM Atilho, KI Brewer, KA Harris, SN Malkowski, ...
RNA biology 15 (3), 377-390, 2018
462018
A bacterial riboswitch class for the thiamin precursor HMP-PP employs a terminator-embedded aptamer
RM Atilho, G Mirihana Arachchilage, EB Greenlee, KM Knecht, ...
Elife 8, e45210, 2019
382019
Targeting of G-Quadruplex Harboring Pre-miRNA 92b by LNA Rescues PTEN Expression in NSCL Cancer Cells
Gayan Mirihana Arachchilage, Prakash Kharel, Joshua Reid, Soumitra Basu
ACS Chemical Biology, 2018
332018
Biochemical validation of a second class of tetrahydrofolate riboswitches in bacteria
X Chen, GM Arachchilage, RR Breaker
Rna 25 (9), 1091-1097, 2019
242019
Stable G-quadruplex enabling sequences are selected against by the context-dependent codon bias
GM Arachchilage, MH Arachchilage, A Venkataraman, H Piontkivska, ...
Gene 696, 149-161, 2019
202019
Comprehensive discovery of novel structured noncoding RNAs in 26 bacterial genomes
KI Brewer, EB Greenlee, G Higgs, D Yu, G Mirihana Arachchilage, X Chen, ...
RNA biology 18 (12), 2417-2432, 2021
152021
Architectures and complex functions of tandem riboswitches
ME Sherlock, G Higgs, D Yu, DL Widner, NA White, N Sudarsan, ...
RNA biology 19 (1), 1059-1076, 2022
112022
Engineered domain swapping indicates context dependent functional role of RNA G-quadruplexes
D Bhattacharyya, MJ Morris, P Kharel, GM Arachchilage, KM Fedeli, ...
Biochimie 137, 147-150, 2017
92017
A library screening approach identifies naturally occurring RNA sequences for a G-quadruplex binding ligand
GM Arachchilage
Chemical communications 50 (10), 1250-1252, 2014
92014
Metal cations in G-quadruplex folding and stability, Front. Chem. 4 (2016) 38
D Bhattacharyya, GM Arachchilage, S Basu
82016
Key players in regulatory RNA realm of bacteria
G Mahendran, OT Jayasinghe, D Thavakumaran, GM Arachchilage, ...
Biochemistry and Biophysics Reports 30, 101276, 2022
62022
Metal cations in G-quadruplex folding and stability. Front Chem. 2016; 4: 38
D Bhattacharyya, G Mirihana Arachchilage, S Basu
52016
Genome‐wide Discovery of Rare Riboswitches in Bacteria
GM Arachchilage, R Atilho, S Stav, G Higgs, R Breaker
The FASEB Journal 33 (S1), 778.8-778.8, 2019
22019
Compounds for treating spinocerebellar ataxia type 3
Gayan Mirihana ARACHCHILAGE, Michael A. Arnold, Scott Barraza, Anuradha ...
WO Patent WO2022169868A1, 2022
2022
Methods for treating spinocerebellar ataxia type 3
Gayan Mirihana ARACHCHILAGE, Michael A. Arnold, Scott Barraza, Anuradha ...
WO Patent WO2022169866A1, 2022
2022
Methods for treating spinocerebellar ataxia type 3
Gayan Mirihana ARACHCHILAGE, Michael A. Arnold, Scott Barraza, Anuradha ...
WO Patent WO2022169864A1, 2022
2022
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