| Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease SL Bernstein, NF Dupuis, ND Lazo, T Wyttenbach, MM Condron, G Bitan, ... Nature chemistry 1 (4), 326-331, 2009 | 1073 | 2009 |
| FROM FOLDING THEORIES TO FOLDING PROTEINS: A Review and Assessment of Simulation Studies of Protein Folding and Unfolding JE Shea, CL Brooks III Annual review of physical chemistry 52 (1), 499-535, 2001 | 633 | 2001 |
| Amyloid oligomers: A joint experimental/computational perspective on Alzheimer’s disease, Parkinson’s disease, type II diabetes, and amyotrophic lateral sclerosis PH Nguyen, A Ramamoorthy, BR Sahoo, J Zheng, P Faller, JE Straub, ... Chemical reviews 121 (4), 2545-2647, 2021 | 536 | 2021 |
| Amyloid β-Protein: Monomer Structure and Early Aggregation States of Aβ42 and Its Pro19 Alloform SL Bernstein, T Wyttenbach, A Baumketner, JE Shea, G Bitan, DB Teplow, ... Journal of the American Chemical Society 127 (7), 2075-2084, 2005 | 419 | 2005 |
| Moltemplate: A tool for coarse-grained modeling of complex biological matter and soft condensed matter physics AI Jewett, D Stelter, J Lambert, SM Saladi, OM Roscioni, M Ricci, L Autin, ... Journal of molecular biology 433 (11), 166841, 2021 | 350 | 2021 |
| Amyloid β‐protein monomer structure: A computational and experimental study A Baumketner, SL Bernstein, T Wyttenbach, G Bitan, DB Teplow, ... Protein Science 15 (3), 420-428, 2006 | 311 | 2006 |
| Elucidating amyloid β-protein folding and assembly: a multidisciplinary approach DB Teplow, ND Lazo, G Bitan, S Bernstein, T Wyttenbach, MT Bowers, ... Accounts of chemical research 39 (9), 635-645, 2006 | 267 | 2006 |
| Exploring the origins of topological frustration: design of a minimally frustrated model of fragment B of protein A JE Shea, JN Onuchic, CL Brooks III Proceedings of the National Academy of Sciences 96 (22), 12512-12517, 1999 | 266 | 1999 |
| Human islet amyloid polypeptide monomers form ordered β-hairpins: a possible direct amyloidogenic precursor NF Dupuis, C Wu, JE Shea, MT Bowers Journal of the American Chemical Society 131 (51), 18283-18292, 2009 | 258 | 2009 |
| Complete phase diagram for liquid–liquid phase separation of intrinsically disordered proteins J McCarty, KT Delaney, SPO Danielsen, GH Fredrickson, JE Shea The journal of physical chemistry letters 10 (8), 1644-1652, 2019 | 254 | 2019 |
| The amyloid formation mechanism in human IAPP: dimers have β-strand monomer− monomer interfaces NF Dupuis, C Wu, JE Shea, MT Bowers Journal of the American Chemical Society 133 (19), 7240-7243, 2011 | 243 | 2011 |
| Role of water in mediating the assembly of Alzheimer amyloid-β Aβ16− 22 protofilaments MG Krone, L Hua, P Soto, R Zhou, BJ Berne, JE Shea Journal of the American Chemical Society 130 (33), 11066-11072, 2008 | 233 | 2008 |
| Coarse-grained models for protein aggregation C Wu, JE Shea Current opinion in structural biology 21 (2), 209-220, 2011 | 227 | 2011 |
| Effects of solvent on the structure of the Alzheimer amyloid-β (25–35) peptide G Wei, JE Shea Biophysical journal 91 (5), 1638-1647, 2006 | 204 | 2006 |
| Regulation and aggregation of intrinsically disordered peptides ZA Levine, L Larini, NE LaPointe, SC Feinstein, JE Shea Proceedings of the National Academy of Sciences 112 (9), 2758-2763, 2015 | 200 | 2015 |
| Binding of Congo red to amyloid protofibrils of the Alzheimer Aβ9–40 peptide probed by molecular dynamics simulations C Wu, J Scott, JE Shea Biophysical journal 103 (3), 550-557, 2012 | 193 | 2012 |
| Computational studies of protein aggregation: methods and applications A Morriss-Andrews, JE Shea Annual review of physical chemistry 66 (1), 643-666, 2015 | 181 | 2015 |
| The binding of thioflavin T and its neutral analog BTA-1 to protofibrils of the Alzheimer’s disease Aβ16–22 peptide probed by molecular dynamics simulations C Wu, Z Wang, H Lei, Y Duan, MT Bowers, JE Shea Journal of molecular biology 384 (3), 718-729, 2008 | 180 | 2008 |
| Structure of the 21–30 fragment of amyloid β‐protein A Baumketner, SL Bernstein, T Wyttenbach, ND Lazo, DB Teplow, ... Protein science 15 (6), 1239-1247, 2006 | 177 | 2006 |
| Tau assembly: the dominant role of PHF6 (VQIVYK) in microtubule binding region repeat R3 P Ganguly, TD Do, L Larini, NE LaPointe, AJ Sercel, MF Shade, ... The journal of physical chemistry B 119 (13), 4582-4593, 2015 | 175 | 2015 |
Michael T BowersProfessor of ChemistryVerified email at ucsb.edu
