| Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ... Nature Communicationsvolume 10 (1), 2674, 2019 | 297 | 2019 |
| The effects of death and post-mortem cold ischemia on human tissue transcriptomes PG Ferreira, M Muñoz-Aguirre, F Reverter, CP Sa Godinho, A Sousa, ... Nature communications 9 (1), 490, 2018 | 278 | 2018 |
| Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial F Rivellese, AEA Surace, K Goldmann, E Sciacca, C Çubuk, G Giorli, ... Nature medicine 28 (6), 1256-1268, 2022 | 153 | 2022 |
| Babelomics 5.0: functional interpretation for new generations of genomic data R Alonso, F Salavert, F Garcia-Garcia, J Carbonell-Caballero, M Bleda, ... Nucleic acids research 43 (W1), W117-W121, 2015 | 140 | 2015 |
| Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis M Razzoli, A Frontini, A Gurney, E Mondini, C Cubuk, LS Katz, C Cero, ... Molecular metabolism 5 (1), 19-33, 2016 | 97 | 2016 |
| High throughput estimation of functional cell activities reveals disease mechanisms and predicts relevant clinical outcomes MR Hidalgo, C Cubuk, A Amadoz, F Salavert, J Carbonell-Caballero, ... Oncotarget 8 (3), 5160, 2017 | 91 | 2017 |
| Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity K Petkevicius, S Virtue, G Bidault, B Jenkins, C Çubuk, C Morgantini, ... elife 8, e47990, 2019 | 62 | 2019 |
| Clinical likelihood ratios and balanced accuracy for 44 in silico tools against multiple large-scale functional assays of cancer susceptibility genes C Cubuk, A Garrett, S Choi, L King, C Loveday, B Torr, GJ Burghel, ... Genetics in Medicine 23 (11), 2096-2104, 2021 | 51 | 2021 |
| A comparison of mechanistic signaling pathway activity analysis methods A Amadoz, MR Hidalgo, C Cubuk, J Carbonell-Caballero, J Dopazo Briefings in bioinformatics 20 (5), 1655-1668, 2019 | 50 | 2019 |
| Gene expression integration into pathway modules reveals a pan-cancer metabolic landscape C Cubuk, MR Hidalgo, A Amadoz, MA Pujana, F Mateo, C Herranz, ... Cancer research 78 (21), 6059-6072, 2018 | 48 | 2018 |
| Role of synovial fibroblast subsets across synovial pathotypes in rheumatoid arthritis: a deconvolution analysis R Micheroli, M Elhai, S Edalat, M Frank-Bertoncelj, K Bürki, A Ciurea, ... RMD Open 8 (doi:10.1136/rmdopen-2021-001949), 2022 | 46 | 2022 |
| Taxonomic variations in the gut microbiome of gout patients with and without tophi might have a functional impact on urate metabolism EO Méndez-Salazar, J Vázquez-Mellado, CS Casimiro-Soriguer, ... Molecular Medicine 27, 1-13, 2021 | 42 | 2021 |
| Combining evidence for and against pathogenicity for variants in cancer susceptibility genes: CanVIG-UK consensus recommendations A Garrett, M Durkie, A Callaway, GJ Burghel, R Robinson, J Drummond, ... Journal of medical genetics, 2020 | 42 | 2020 |
| Cancer Variant Interpretation Group UK (CanVIG-UK): an exemplar national subspecialty multidisciplinary network A Garrett, A Callaway, M Durkie, C Cubuk, M Alikian, GJ Burghel, ... Journal of Medical Genetics, 2020 | 37 | 2020 |
| Models of cell signaling uncover molecular mechanisms of high-risk neuroblastoma and predict disease outcome MR Hidalgo, A Amadoz, C Çubuk, J Carbonell-Caballero, J Dopazo Biology direct 13 (1), 1-12, 2018 | 35 | 2018 |
| Differential metabolic activity and discovery of therapeutic targets using summarized metabolic pathway models C Cubuk, MR Hidalgo, A Amadoz, K Rian, F Salavert, MA Pujana, ... npj Systems Biology and Applications 5 (1), 2019 | 34 | 2019 |
| Actionable pathways: interactive discovery of therapeutic targets using signaling pathway models F Salavert, MR Hidago, A Amadoz, C Cubuk, I Medina, D Crespo, ... Nucleic acids research 44 (W1), W212-W216, 2016 | 33 | 2016 |
| Tissue expression of MLH1, PMS2, MSH2, and MSH6 proteins and prognostic value of microsatellite instability in Wilms tumor: experience of 45 cases G Diniz, S Aktas, C Cubuk, R Ortac, C Vergin, N Olgun Pediatric hematology and oncology 30 (4), 273-284, 2013 | 30 | 2013 |
| Community Assessment of the Predictability of Cancer Protein and Phosphoprotein Levels from Genomics and Transcriptomics M Yang, F Petralia, Z Li, H Li, W Ma, X Song, S Kim, H Lee, H Yu, B Lee, ... Cell Systems 11 (2), 186-195. e9, 2020 | 25 | 2020 |
| Mechanistic modeling of the SARS-CoV-2 disease map K Rian, M Esteban-Medina, MR Hidalgo, C Çubuk, MM Falco, C Loucera, ... BioData mining 14, 1-8, 2021 | 23 | 2021 |
