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Pr Philippe Compain
Pr Philippe Compain
Professor of Organic Chemistry, Strasbourg University
Dirección de correo verificada de unistra.fr - Página principal
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Iminosugars: from synthesis to therapeutic applications
P Compain, OR Martin
John Wiley & Sons, 2007
6002007
Carbohydrate mimetics-based glycosyltransferase inhibitors
P Compain, OR Martin
Bioorganic & medicinal chemistry 9 (12), 3077-3092, 2001
4432001
Design, synthesis and biological evaluation of iminosugar-based glycosyltransferase inhibitors
P Compain, OR Martin
Current topics in medicinal chemistry 3 (5), 541-560, 2003
2472003
Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect
P Compain, C Decroocq, J Iehl, M Holler, D Hazelard, T Mena Barragan, ...
Angewandte Chemie 122 (33), 5889-5892, 2010
2202010
Olefin metathesis of amine‐containing systems: beyond the current consensus
P Compain
Advanced Synthesis & Catalysis 349 (11‐12), 1829-1846, 2007
2092007
Design and synthesis of highly potent and selective pharmacological chaperones for the treatment of Gaucher's disease
P Compain, OR Martin, C Boucheron, G Godin, L Yu, K Ikeda, N Asano
ChemBioChem 7 (9), 1356-1359, 2006
2012006
Tactics and strategies for the synthesis of iminosugar C-glycosides: a review
P Compain, V Chagnault, OR Martin
Tetrahedron: Asymmetry 20 (6-8), 672-711, 2009
1722009
Catalytic C–H amination at its limits: challenges and solutions
D Hazelard, PA Nocquet, P Compain
Organic Chemistry Frontiers 4 (12), 2500-2521, 2017
1332017
α-1-C-Octyl-1-deoxynojirimycin as a pharmacological chaperone for Gaucher disease
L Yu, K Ikeda, A Kato, I Adachi, G Godin, P Compain, O Martin, N Asano
Bioorganic & medicinal chemistry 14 (23), 7736-7744, 2006
1282006
The multivalent effect in glycosidase inhibition: A new, rapidly emerging topic in glycoscience
P Compain, A Bodlenner
ChemBioChem 15 (9), 1239-1251, 2014
1142014
The multivalent effect in glycosidase inhibition: Probing the influence of architectural parameters with cyclodextrin‐based iminosugar click clusters
C Decroocq, D Rodríguez‐Lucena, V Russo, T Mena Barragan, ...
Chemistry–A European Journal 17 (49), 13825-13831, 2011
1092011
Iminosugar-based glycopolypeptides: glycosidase inhibition with bioinspired glycoprotein analogue micellar self-assemblies
C Bonduelle, J Huang, T Mena-Barragán, CO Mellet, C Decroocq, ...
Chemical Communications 50 (25), 3350-3352, 2014
852014
Cyclodextrin‐based iminosugar click clusters: the first examples of multivalent pharmacological chaperones for the treatment of lysosomal storage disorders
C Decroocq, D Rodríguez‐Lucena, K Ikeda, N Asano, P Compain
ChemBioChem 13 (5), 661-664, 2012
842012
First total synthesis of (+)-hyacinthacine A2
L Rambaud, P Compain, OR Martin
Tetrahedron: Asymmetry 12 (13), 1807-1809, 2001
842001
A General Strategy for the Practical Synthesis of Nojirimycin C-Glycosides and Analogues. Extension to the First Reported Example of an Iminosugar 1-Phosphonate
G Godin, P Compain, G Masson, OR Martin
The Journal of Organic Chemistry 67 (20), 6960-6970, 2002
802002
Second‐generation iminoxylitol‐based pharmacological chaperones for the treatment of Gaucher disease
F Oulaïdi, S Front‐Deschamps, E Gallienne, E Lesellier, K Ikeda, N Asano, ...
ChemMedChem 6 (2), 353-361, 2011
682011
New Aspects of Catalytic Intramolecular C− H Amination: Unexpected Formation of a Seven-Membered Ring in Nitrogen-Containing Systems
S Toumieux, P Compain, OR Martin, M Selkti
Organic Letters 8 (20), 4493-4496, 2006
662006
The multivalent effect in glycosidase inhibition: Probing the influence of valency, peripheral ligand structure, and topology with cyclodextrin‐based iminosugar click clusters
C Decroocq, A Joosten, R Sergent, T Mena Barragan, C Ortiz Mellet, ...
ChemBioChem 14 (15), 2038-2049, 2013
652013
General Access to Iminosugar C-Glycoside Building Blocks by Means of Cross-Metathesis:  A Gateway to Glycoconjugate Mimetics
G Godin, P Compain, OR Martin
Organic Letters 5 (18), 3269-3272, 2003
642003
A systematic investigation of iminosugar click clusters as pharmacological chaperones for the treatment of Gaucher disease
A Joosten, C Decroocq, J de Sousa, JP Schneider, E Etamé, A Bodlenner, ...
ChemBioChem 15 (2), 309-319, 2014
622014
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