Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10603 | 2021 |
Signalling, inflammation and arthritis: NF-κB and its relevance to arthritis and inflammation RE Simmonds, BM Foxwell Rheumatology 47 (5), 584-590, 2008 | 422 | 2008 |
Coagulation, inflammation, and apoptosis: different roles for protein S and the protein S–C4b binding protein complex SM Rezende, RE Simmonds, DA Lane Blood 103 (4), 1192-1201, 2004 | 286 | 2004 |
Protein S deficiency: a database of mutations–summary of the first update S Gandrille, D Borgel, N Sala, Y Espinosa-Parrilla, R Simmonds, ... Thrombosis and haemostasis 84 (11), 918-918, 2000 | 170 | 2000 |
The Pathogenic Mechanism of the Mycobacterium ulcerans Virulence Factor, Mycolactone, Depends on Blockade of Protein Translocation into the ER BS Hall, K Hill, M McKenna, J Ogbechi, S High, AE Willis, RE Simmonds PLoS pathogens 10 (4), e1004061, 2014 | 155 | 2014 |
Protein S deficiency: a database of mutations S Gandrille, D Borgel, H Ireland, DA Lane, R Simmonds, PH Reitsma, ... Thrombosis and haemostasis 77 (06), 1201-1214, 1997 | 133 | 1997 |
Clarification of the risk for venous thrombosis associated with hereditary protein S deficiency by investigation of a large kindred with a characterized gene defect RE Simmonds, H Ireland, DA Lane, B Zoller, PG de Frutos, B Dahlback Annals of internal medicine 128 (1), 8-14, 1998 | 132 | 1998 |
Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures SM Sacre, A Lo, B Gregory, RE Simmonds, L Williams, M Feldmann, ... The Journal of Immunology 181 (11), 8002-8009, 2008 | 121 | 2008 |
Mycolactone inhibits monocyte cytokine production by a posttranscriptional mechanism RE Simmonds, FV Lali, T Smallie, PLC Small, BM Foxwell The Journal of Immunology 182 (4), 2194-2202, 2009 | 120 | 2009 |
Structural and Functional Implications of the Intron/Exon Organization of the Human Endothelial Cell Protein C/Activated Protein C Receptor (EPCR) Gene: Comparison With the … RE Simmonds, DA Lane Blood, The Journal of the American Society of Hematology 94 (2), 632-641, 1999 | 120 | 1999 |
Genetic and phenotypic analysis of a large (122-member) protein S–deficient kindred provides an explanation for the familial coexistence of type I and type III plasma phenotypes RE Simmonds, B Zöller, H Ireland, E Thompson, P Garcı́a de Frutos, ... Blood, The Journal of the American Society of Hematology 89 (12), 4364-4370, 1997 | 115 | 1997 |
Factor V Leiden (G1691A) and prothrombin gene G20210A mutations as potential risk factors for venous thromboembolism after total hip or total knee replacement surgery K Wåhlander, G Larson, TL Lindahl, C Andersson, L Frison, D Gustafsson, ... Thrombosis and haemostasis 87 (04), 580-585, 2002 | 99 | 2002 |
Recent advances: role of mycolactone in the pathogenesis and monitoring of Mycobacterium ulcerans infection/Buruli ulcer disease FS Sarfo, R Phillips, M Wansbrough‐Jones, RE Simmonds Cellular microbiology 18 (1), 17-29, 2016 | 98 | 2016 |
Mechanistic insights into the inhibition of Sec61-dependent co-and post-translational translocation by mycolactone M McKenna, RE Simmonds, S High Journal of cell science 129 (7), 1404-1415, 2016 | 94 | 2016 |
Buruli ulcer: a review of the current knowledge RR Yotsu, K Suzuki, RE Simmonds, R Bedimo, A Ablordey, ... Current tropical medicine reports 5, 247-256, 2018 | 93 | 2018 |
A common 4G allele in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene as a risk factor for pulmonary embolism and arterial thrombosis in hereditary protein S … B Zöller, PG de Frutos, B Dahlbäck Thrombosis and haemostasis 79 (04), 802-807, 1998 | 89 | 1998 |
Haemostatic genetic risk factors in arterial thrombosis RE Simmonds, J Hermida, SM Rezende, DA Lane Thrombosis and haemostasis 86 (07), 374-385, 2001 | 85 | 2001 |
Vitamin K–dependent protein S: beyond the protein C pathway B Dahlbäck Seminars in thrombosis and hemostasis 44 (02), 176-184, 2018 | 81 | 2018 |
Pleiotropic molecular effects of the Mycobacterium ulcerans virulence factor mycolactone underlying the cell death and immunosuppression seen in Buruli ulcer B Hall, R Simmonds Biochemical Society Transactions 42 (1), 177-183, 2014 | 67 | 2014 |
Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4 J Ogbechi, BS Hall, T Sbarrato, J Taunton, AE Willis, RC Wek, ... Cell death & disease 9 (3), 397, 2018 | 66 | 2018 |