| Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ RT Nolte, GB Wisely, S Westin, JE Cobb, MH Lambert, R Kurokawa, ... Nature 395 (6698), 137-143, 1998 | 2445 | 1998 |
| Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα HE Xu, TB Stanley, VG Montana, MH Lambert, BG Shearer, JE Cobb, ... Nature 415 (6873), 813-817, 2002 | 757 | 2002 |
| Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation EM McInerney, DW Rose, SE Flynn, S Westin, TM Mullen, A Krones, ... Genes & development 12 (21), 3357-3368, 1998 | 749 | 1998 |
| Asymmetry in the PPARγ/RXRα crystal structure reveals the molecular basis of heterodimerization among nuclear receptors RT Gampe, VG Montana, MH Lambert, AB Miller, RK Bledsoe, MV Milburn, ... Molecular cell 5 (3), 545-555, 2000 | 740 | 2000 |
| Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors HE Xu, MH Lambert, VG Montana, KD Plunket, LB Moore, JL Collins, ... Proceedings of the National Academy of Sciences 98 (24), 13919-13924, 2001 | 678 | 2001 |
| Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity RX Xu, AM Hassell, D Vanderwall, MH Lambert, WD Holmes, MA Luther, ... Science 288 (5472), 1822-1825, 2000 | 438 | 2000 |
| Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators S Westin, R Kurokawa, RT Nolte, GB Wisely, EM McInerney, DW Rose, ... Nature 395 (6698), 199-202, 1998 | 433 | 1998 |
| Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor MJ Eck, S Dhe-Paganon, T Trüb, RT Nolte, SE Shoelson Cell 85 (5), 695-705, 1996 | 420 | 1996 |
| Discovery of 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular … PA Harris, A Boloor, M Cheung, R Kumar, RM Crosby, RG Davis-Ward, ... Journal of medicinal chemistry 51 (15), 4632-4640, 2008 | 405 | 2008 |
| Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance B He, RT Gampe, AJ Kole, AT Hnat, TB Stanley, G An, EL Stewart, ... Molecular cell 16 (3), 425-438, 2004 | 372 | 2004 |
| The complete sequence and structural analysis of human apolipoprotein B‐100: relationship between apoB‐100 and apoB‐48 forms. C Cladaras, M Hadzopoulou‐Cladaras, RT Nolte, D Atkinson, VI Zannis The EMBO journal 5 (13), 3495-3507, 1986 | 333 | 1986 |
| Differing roles for zinc fingers in DNA recognition: structure of a six-finger transcription factor IIIA complex RT Nolte, RM Conlin, SC Harrison, RS Brown Proceedings of the National Academy of Sciences 95 (6), 2938-2943, 1998 | 313 | 1998 |
| A structural basis for constitutive activity in the human CAR/RXRα heterodimer RX Xu, MH Lambert, BB Wisely, EN Warren, EE Weinert, GM Waitt, ... Molecular cell 16 (6), 919-928, 2004 | 262 | 2004 |
| Discovery of novel benzimidazoles as potent inhibitors of TIE-2 and VEGFR-2 tyrosine kinase receptors M Hasegawa, N Nishigaki, Y Washio, K Kano, PA Harris, H Sato, I Mori, ... Journal of medicinal chemistry 50 (18), 4453-4470, 2007 | 240 | 2007 |
| Crystallization of protein–ligand complexes AM Hassell, G An, RK Bledsoe, JM Bynum, HL Carter, SJJ Deng, ... Acta Crystallographica Section D: Biological Crystallography 63 (1), 72-79, 2007 | 235 | 2007 |
| Conformational analysis of apolipoprotein AI and E-3 based on primary sequence and circular dichroism RT Nolte, D Atkinson Biophysical journal 63 (5), 1221-1239, 1992 | 217 | 1992 |
| The crystal structure of nucleoplasmin-core: implications for histone binding and nucleosome assembly S Dutta, IV Akey, C Dingwall, KL Hartman, T Laue, RT Nolte, JF Head, ... Molecular cell 8 (4), 841-853, 2001 | 214 | 2001 |
| Novel 4-amino-furo[2,3-d]pyrimidines as Tie-2 and VEGFR2 dual inhibitors Y Miyazaki, S Matsunaga, J Tang, Y Maeda, M Nakano, RJ Philippe, ... Bioorganic & medicinal chemistry letters 15 (9), 2203-2207, 2005 | 184 | 2005 |
| Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix RT Gampe, VG Montana, MH Lambert, GB Wisely, MV Milburn, HE Xu Genes & development 14 (17), 2229-2241, 2000 | 175 | 2000 |
| Crystal structure of the PI 3-kinase p85 amino-terminal SH2 domain and its phosphopeptide complexes RT Nolte, MJ Eck, J Schlessinger, SE Shoelson, SC Harrison Nature structural biology 3 (4), 364-374, 1996 | 172 | 1996 |
