| Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models NH Holford, LB Sheiner Clinical Pharmacokinetics 6 (6), 429-53, 1981 | 1520 | 1981 |
| Mechanism-based concepts of size and maturity in pharmacokinetics BJ Anderson, NHG Holford Annu. Rev. Pharmacol. Toxicol. 48 (1), 303-332, 2008 | 1163 | 2008 |
| Mechanistic basis of using body size and maturation to predict clearance in humans BJ Anderson, NHG Holford Drug metabolism and pharmacokinetics 24 (1), 25-36, 2009 | 547 | 2009 |
| Human renal function maturation: a quantitative description using weight and postmenstrual age MM Rhodin, BJ Anderson, AM Peters, MG Coulthard, B Wilkins, M Cole, ... Pediatric nephrology 24, 67-76, 2009 | 502 | 2009 |
| A pharmacokinetic standard for babies and adults N Holford, YA Heo, B Anderson Journal of pharmaceutical sciences 102 (9), 2941-2952, 2013 | 384 | 2013 |
| Model evaluation of continuous data pharmacometric models: metrics and graphics THT Nguyen, MS Mouksassi, N Holford, N Al‐Huniti, I Freedman, ... CPT: pharmacometrics & systems pharmacology 6 (2), 87-109, 2017 | 345 | 2017 |
| Phase 1 clinical results with tandutinib (MLN518), a novel FLT3 antagonist, in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome: safety … DJ DeAngelo, RM Stone, ML Heaney, SD Nimer, RL Paquette, ... Blood 108 (12), 3674-3681, 2006 | 326 | 2006 |
| The visual predictive check—superiority to standard diagnostic (Rorschach) plots N Holford Abstr 738, 14, 2005 | 260 | 2005 |
| Clinical trial simulation: a review N Holford, SC Ma, BA Ploeger Clinical Pharmacology & Therapeutics 88 (2), 166-182, 2010 | 232 | 2010 |
| Influence of obesity on propofol pharmacokinetics: derivation of a pharmacokinetic model LI Cortinez, BJ Anderson, A Penna, L Olivares, HR Munoz, NHG Holford, ... British journal of anaesthesia 105 (4), 448-456, 2010 | 224 | 2010 |
| A tutorial on visual predictive checks MO Karlsson, N Holford abstr 1434, 17, 2008 | 217 | 2008 |
| Understanding dosing: children are small adults, neonates are immature children BJ Anderson, NHG Holford Archives of disease in childhood 98 (9), 737-744, 2013 | 213 | 2013 |
| A review of mixed‐effects models of tumor growth and effects of anticancer drug treatment used in population analysis B Ribba, NH Holford, P Magni, I Trocóniz, I Gueorguieva, P Girard, C Sarr, ... CPT: pharmacometrics & systems pharmacology 3 (5), 1-10, 2014 | 209 | 2014 |
| Drug treatment effects on disease progression PLS Chan, NHG Holford Annual review of pharmacology and toxicology 41 (1), 625-659, 2001 | 201 | 2001 |
| Tips and traps analyzing pediatric PK data BJ Anderson, NHG Holford Pediatric Anesthesia 21 (3), 222-237, 2011 | 184 | 2011 |
| Morphine pharmacokinetics and pharmacodynamics in preterm and term neonates: secondary results from the NEOPAIN trial KJS Anand, BJ Anderson, NHG Holford, RW Hall, T Young, B Shephard, ... British journal of anaesthesia 101 (5), 680-689, 2008 | 184 | 2008 |
| Negligible excretion of unchanged ketoprofen, naproxen, and probenecid in urine RA Upton, JN Buskin, RL Williams, NHG Holford, S Riegelman Journal of pharmaceutical sciences 69 (11), 1254-1257, 1980 | 150 | 1980 |
| Importance of hematocrit for a tacrolimus target concentration strategy E Størset, N Holford, K Midtvedt, S Bremer, S Bergan, A Åsberg European journal of clinical pharmacology 70, 65-77, 2014 | 149 | 2014 |
| Paracetamol plasma and cerebrospinal fluid pharmacokinetics in children BJ Anderson, NHG Holford, GA Woollard, PLS Chan British journal of clinical pharmacology 46 (3), 237-243, 1998 | 139 | 1998 |
| Allometric size: the scientific theory and extension to normal fat mass NHG Holford, BJ Anderson European Journal of Pharmaceutical Sciences 109, S59-S64, 2017 | 120 | 2017 |
