Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group M Lobera, KP Madauss, DT Pohlhaus, QG Wright, M Trocha, DR Schmidt, ... Nature chemical biology 9 (5), 319-325, 2013 | 365 | 2013 |
A Ligand-mediated Hydrogen Bond Network Required for the Activation of the Mineralocorticoid Receptor*[boxs] RK Bledsoe, KP Madauss, JA Holt, CJ Apolito, MH Lambert, KH Pearce, ... Journal of Biological Chemistry 280 (35), 31283-31293, 2005 | 228 | 2005 |
Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation M Pariollaud, JE Gibbs, TW Hopwood, S Brown, N Begley, R Vonslow, ... The Journal of clinical investigation 128 (6), 2281-2296, 2018 | 156 | 2018 |
Optimized chemical probes for REV-ERBα RP Trump, S Bresciani, AWJ Cooper, JP Tellam, J Wojno, J Blaikley, ... Journal of medicinal chemistry 56 (11), 4729-4737, 2013 | 94 | 2013 |
Chemical compounds R Cadilla, A Larkin, E Stewart, R Trump, P Turnbull US Patent App. 10/560,017, 2006 | 35 | 2006 |
Structure guided design of 5-arylindazole glucocorticoid receptor agonists and antagonists CM Yates, PJ Brown, EL Stewart, C Patten, RJH Austin, JA Holt, ... Journal of medicinal chemistry 53 (11), 4531-4544, 2010 | 32 | 2010 |
Design and synthesis of an array of selective androgen receptor modulators RP Trump, JBE Blanc, EL Stewart, PJ Brown, M Caivano, DW Gray, ... Journal of Combinatorial Chemistry 9 (1), 107-114, 2007 | 32 | 2007 |
Co-crystal structure guided array synthesis of PPARγ inverse agonists RP Trump, JE Cobb, BG Shearer, MH Lambert, RT Nolte, TM Willson, ... Bioorganic & Medicinal Chemistry Letters 17 (14), 3916-3920, 2007 | 28 | 2007 |
Amino acid-derived heterocycles as combinatorial library targets: spirocyclic ketal lactones RP Trump, PA Bartlett Journal of Combinatorial Chemistry 5 (3), 285-291, 2003 | 22 | 2003 |
Chemical compounds JB Blanc, R Cadilla, D Cowan, I Kaldor, A Larkin, E Stewart, R Trump, ... US Patent App. 10/560,012, 2006 | 21 | 2006 |
Probing the reactivity of solid supports via Hammett relationships SW Gerritz, RP Trump, WJ Zuercher Journal of the American Chemical Society 122 (27), 6357-6363, 2000 | 21 | 2000 |
RU486 did not exacerbate cytokine release in mice challenged with LPS nor in db/db mice B Yang, RP Trump, Y Shen, JA McNulty, LG Clifton, SA Stimpson, P Lin, ... BMC pharmacology 8, 1-10, 2008 | 19 | 2008 |
The identification a novel, selective, non-steroidal, functional glucocorticoid receptor antagonist J Rimland, A Dunne, SS Hunjan, R Sasse, I Uings, D Montanari, ... Bioorganic & Medicinal Chemistry Letters 20 (7), 2340-2343, 2010 | 17 | 2010 |
Virtual hydrocarbon and combinatorial databases for use with CAVEAT Y Yang, DV Nesterenko, RP Trump, K Yamaguchi, PA Bartlett, ... Journal of chemical information and modeling 45 (6), 1820-1823, 2005 | 16 | 2005 |
Nuclear receptor ligands in inflammatory lung diseases L Ramamurthy, RP Trump Drug Discovery Today: Disease Mechanisms 3 (1), 85-90, 2006 | 1 | 2006 |
Aniline derivatived androgen-, glucocorticoid-, mineralcorticoid-and progesterone-receptor modulators JBE Blanc, R Cadilla, DJ Cowan, I Kaldor, AL Larkin, EL Stewart, ... | 1 | 2005 |
Novel cyclization reactions for combinatorial chemistry. PA Bartlett, JG Lewis, DD Johnson, RP Trump ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 213, 273-ORGN, 1997 | 1 | 1997 |
COMPOUNDS AND METHODS S GHOSH, M LOBERA, R TRUMP, C ZHANG WO Patent 2,013,066,838, 2013 | | 2013 |
COMPOUNDS AND METHODS S GHOSH, M LOBERA, R TRUMP, C ZHANG WO Patent 2,013,066,832, 2013 | | 2013 |
COMPOUNDS AND METHODS TO INHIBIT HISTONE DEACETYLASE (HDAC) ENZYMES S GHOSH, M LOBERA, R TRUMP, C ZHANG WO Patent 2,013,066,833, 2013 | | 2013 |