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Alejandro Buschiazzo
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The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
A Buschiazzo, MF Amaya, ML Cremona, AC Frasch, PM Alzari
Molecular cell 10 (4), 757-768, 2002
2852002
Trypanosoma c ruzi Trans-sialidase Operates through a Covalent Sialyl-Enzyme Intermediate: Tyrosine Is the Catalytic Nucleophile
AG Watts, I Damager, ML Amaya, A Buschiazzo, P Alzari, AC Frasch, ...
Journal of the American Chemical Society 125 (25), 7532-7533, 2003
2722003
Structural insights into the catalytic mechanism of Trypanosoma cruzi trans-sialidase
MF Amaya, AG Watts, I Damager, A Wehenkel, T Nguyen, A Buschiazzo, ...
Structure 12 (5), 775-784, 2004
2562004
What Makes a Bacterial Species Pathogenic?: Comparative Genomic Analysis of the Genus Leptospira
DE Fouts, MA Matthias, H Adhikarla, B Adler, L Amorim-Santos, DE Berg, ...
PLOS Negl Trop Dis 10 (2), e0004403, 2016
2552016
Structural plasticity and catalysis regulation of a thermosensor histidine kinase
D Albanesi, M Martín, F Trajtenberg, MC Mansilla, A Haouz, PM Alzari, ...
Proceedings of the National Academy of Sciences 106 (38), 16185-16190, 2009
2102009
Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation
A Buschiazzo, JE Ugalde, ME Guerin, W Shepard, RA Ugalde, PM Alzari
The EMBO journal 23 (16), 3196-3205, 2004
1872004
Active nuclear import and cytoplasmic retention of activation-induced deaminase
AM Patenaude, A Orthwein, Y Hu, VA Campo, B Kavli, A Buschiazzo, ...
Nature structural & molecular biology 16 (5), 517-527, 2009
1672009
Structural basis of sialyltransferase activity in trypanosomal sialidases
A Buschiazzo, GA Tavares, O Campetella, S Spinelli, ML Cremona, ...
The EMBO journal 19 (1), 16-24, 2000
1672000
Identification of the gene (s) coding for the trans‐sialidase of Trypanosoma cruzi.
AJ Parodi, GD Pollevick, M Mautner, A Buschiazzo, DO Sanchez, ...
The EMBO journal 11 (5), 1705-1710, 1992
1461992
Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria
ME Guerin, J Kordulakova, F Schaeffer, Z Svetlikova, A Buschiazzo, ...
Journal of Biological Chemistry 282 (28), 20705-20714, 2007
1392007
A New Generation of Specific Trypanosoma cruzi trans‐Sialidase Inhibitors
S Buchini, A Buschiazzo, SG Withers
Angewandte Chemie 120 (14), 2740-2743, 2008
1242008
Structural basis of lipid biosynthesis regulation in Gram‐positive bacteria
GE Schujman, M Guerin, A Buschiazzo, F Schaeffer, LI Llarrull, G Reh, ...
The EMBO journal 25 (17), 4074-4083, 2006
1192006
Structural and kinetic analysis of two covalent sialosyl-enzyme intermediates on Trypanosoma rangeli sialidase
AG Watts, P Oppezzo, SG Withers, PM Alzari, A Buschiazzo
Journal of Biological Chemistry 281 (7), 4149-4155, 2006
1142006
Crystal structure, catalytic mechanism, and mitogenic properties of Trypanosoma cruzi proline racemase
A Buschiazzo, M Goytia, F Schaeffer, W Degrave, W Shepard, C Grégoire, ...
Proceedings of the National Academy of Sciences of the United States of …, 2006
1132006
Phylogenetic analysis of bovine leukemia viruses isolated in South America reveals diversification in seven distinct genotypes
G Moratorio, G Obal, A Dubra, A Correa, S Bianchi, A Buschiazzo, ...
Archives of virology 155 (4), 481-489, 2010
1062010
Structural insights into sialic acid enzymology
A Buschiazzo, PM Alzari
Current opinion in chemical biology 12 (5), 565-572, 2008
1002008
Data publication with the structural biology data grid supports live analysis
PA Meyer, S Socias, J Key, E Ransey, EC Tjon, A Buschiazzo, M Lei, ...
Nature Communications 7, 10882, 2016
952016
The High Resolution Structures of Free and Inhibitor-bound Trypanosoma rangeli Sialidase and its Comparison with T. cruziTrans-sialidase
MF Amaya, A Buschiazzo, T Nguyen, PM Alzari
Journal of molecular biology 325 (4), 773-784, 2003
902003
The trans‐sialidase from the african trypanosome Trypanosoma brucei
G Montagna, ML Cremona, G Paris, MF Amaya, A Buschiazzo, PM Alzari, ...
The FEBS Journal 269 (12), 2941-2950, 2002
822002
Kinetic and Mechanistic Analysis of Trypanosoma cruzi Trans-Sialidase Reveals a Classical Ping-Pong Mechanism with Acid/Base Catalysis†
I Damager, S Buchini, MF Amaya, A Buschiazzo, P Alzari, AC Frasch, ...
Biochemistry 47 (11), 3507-3512, 2008
812008
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